日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Epithelial-intrinsic nitric oxide synthase 2 sustains host-microbiota dynamics that promote colitis

上皮内源性一氧化氮合酶2维持宿主-微生物群动态平衡,从而促进结肠炎的发生。

Hashimoto-Hill, Seika; Hunt, Bryce; Cole, Sekani; Negi, Shikha; Waddell, Amanda; Yang, Zi F; Wayman, Joseph A; Ollberding, Nicholas J; Miraldi, Emily R; Lim, Hee-Woong; Vazquez-Torres, Andres; Morrison, Thomas E; Denson, Lee A; Alenghat, Theresa

Patient-derived colon epithelial organoids reveal lipid-related metabolic dysfunction in pediatric ulcerative colitis

患者来源的结肠上皮类器官揭示了儿童溃疡性结肠炎中与脂质相关的代谢功能障碍

Ojo, Babajide A; Heo, Lyong; Fox, Sejal R; Waddell, Amanda; Moreno-Fernandez, Maria E; Gibson, Marielle; Tran, Tracy; Dunn, Ashley L; Elknawy, Essam I A; Saini, Neetu; López-Rivera, Javier A; Divanovic, Senad; de Jesus Perez, Vinicio A; Rosen, Michael J

Multicenter Cohort Study of Infliximab Pharmacokinetics and Therapy Response in Pediatric Acute Severe Ulcerative Colitis

一项关于英夫利昔单抗在儿童急性重症溃疡性结肠炎中的药代动力学和治疗反应的多中心队列研究

Whaley, Kaitlin G; Xiong, Ye; Karns, Rebekah; Hyams, Jeffrey S; Kugathasan, Subra; Boyle, Brendan M; Walters, Thomas D; Kelsen, Judith; LeLeiko, Neal; Shapiro, Jason; Waddell, Amanda; Fox, Sejal; Bezold, Ramona; Bruns, Stephanie; Widing, Robin; Haberman, Yael; Collins, Margaret H; Mizuno, Tomoyuki; Minar, Phillip; D'Haens, Geert R; Denson, Lee A; Vinks, Alexander A; Rosen, Michael J

Microbiota-derived butyrate dampens linaclotide stimulation of the guanylate cyclase C pathway in patient-derived colonoids

微生物群衍生的丁酸盐可抑制利那洛肽对患者来源结肠类器官中鸟苷酸环化酶C通路的刺激作用

Velez Lopez, Alejandro; Waddell, Amanda; Antonacci, Simona; Castillo, Daniel; Santucci, Neha; Ollberding, Nicholas J; Eshleman, Emily M; Denson, Lee A; Alenghat, Theresa

Mucosal Expression of Type 2 and Type 17 Immune Response Genes Distinguishes Ulcerative Colitis From Colon-Only Crohn's Disease in Treatment-Naive Pediatric Patients

黏膜中2型和17型免疫反应基因的表达可区分未经治疗的儿科患者的溃疡性结肠炎和仅累及结肠的克罗恩病

Rosen, Michael J; Karns, Rebekah; Vallance, Jefferson E; Bezold, Ramona; Waddell, Amanda; Collins, Margaret H; Haberman, Yael; Minar, Phillip; Baldassano, Robert N; Hyams, Jeffrey S; Baker, Susan S; Kellermayer, Richard; Noe, Joshua D; Griffiths, Anne M; Rosh, Joel R; Crandall, Wallace V; Heyman, Melvin B; Mack, David R; Kappelman, Michael D; Markowitz, James; Moulton, Dedrick E; Leleiko, Neal S; Walters, Thomas D; Kugathasan, Subra; Wilson, Keith T; Hogan, Simon P; Denson, Lee A

NKT cells can help mediate the protective effects of 1,25-dihydroxyvitamin D3 in experimental autoimmune encephalomyelitis in mice

NKT细胞可以帮助介导1,25-二羟基维生素D3在小鼠实验性自身免疫性脑脊髓炎中的保护作用。

Waddell, Amanda; Zhao, Jun; Cantorna, Margherita T

Dominant effects of the diet on the microbiome and the local and systemic immune response in mice

饮食对小鼠肠道菌群以及局部和全身免疫反应的主要影响

Ooi, Jot Hui; Waddell, Amanda; Lin, Yang-Ding; Albert, Istvan; Rust, Laura T; Holden, Victoria; Cantorna, Margherita T

CD14+CD33+ myeloid cell-CCL11-eosinophil signature in ulcerative colitis.

溃疡性结肠炎中 CD14+CD33+ 髓系细胞-CCL11-嗜酸性粒细胞特征

Lampinen Maria, Waddell Amanda, Ahrens Richard, Carlson Marie, Hogan Simon P

Eosinophils in infection and intestinal immunity

嗜酸性粒细胞在感染和肠道免疫中的作用

Hogan, Simon P; Waddell, Amanda; Fulkerson, Patricia C

Structures of SPOP-substrate complexes: insights into molecular architectures of BTB-Cul3 ubiquitin ligases

SPOP-底物复合物的结构:深入了解BTB-Cul3泛素连接酶的分子结构

Min Zhuang, Matthew F Calabrese, Jiang Liu, M Brett Waddell, Amanda Nourse, Michal Hammel, Darcie J Miller, Helen Walden, David M Duda, Steven N Seyedin, Timothy Hoggard, J Wade Harper, Kevin P White, Brenda A Schulman