日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Development of a succinyl CoA:3-ketoacid CoA transferase inhibitor selective for peripheral tissues that improves glycemia in obesity.

开发一种对周围组织具有选择性的琥珀酰辅酶A:3-酮酸辅酶A转移酶抑制剂,可改善肥胖症患者的血糖水平

Tabatabaei Dakhili Seyed Amirhossein, Yang Kunyan, Al Nebaihi Hamdah, Greenwell Amanda A, Wuest Melinda, Woodfield Jenilee, Farraj Rabih Abou, Saed Christina T, Chan Jordan S F, Bhat Rakesh K, Mangra-Bala Indiresh A, Shafaati Tanin, Gopal Keshav, Eaton Farah, Ferrari Sally R, Wagg Cory S, Capozzi Megan E, Campbell Jonathan E, Overduin Michael, Velazquez-Martinez Carlos A, Glover J N Mark, Wuest Frank, Brocks Dion R, Ussher John R

Alterations of myocardial ketone metabolism in heart failure with preserved ejection fraction (HFpEF).

射血分数保留型心力衰竭(HFpEF)中心肌酮代谢的改变

Sun Qiuyu, Wagg Cory S, Wong Nathan, Wei Kaleigh, Ketema Ezra B, Zhang Liyan, Fang Liye, Seubert John M, Lopaschuk Gary D

Pharmacological Inhibition of Succinyl Coenzyme A:3-Ketoacid Coenzyme A Transferase Alleviates the Progression of Diabetic Cardiomyopathy

琥珀酰辅酶A:3-酮酸辅酶A转移酶的药理学抑制可缓解糖尿病心肌病的进展

Greenwell, Amanda A; Tabatabaei Dakhili, Seyed Amirhossein; Wagg, Cory S; Saed, Christina T; Chan, Jordan S F; Yang, Kunyan; Mangra-Bala, Indiresh A; Stenlund, Magnus J; Eaton, Farah; Gopal, Keshav; Dyck, Jason R B; Lopaschuk, Gary D; Ussher, John R

p53-Mediated Repression of the PGC1A (PPARG Coactivator 1α) and APLNR (Apelin Receptor) Signaling Pathways Limits Fatty Acid Oxidation Energetics: Implications for Cardio-oncology

p53介导的PGC1A(PPARG共激活因子1α)和APLNR(Apelin受体)信号通路抑制限制脂肪酸氧化能量:对心血管肿瘤学的启示

Saleme, Bruno; Das, Subhash K; Zhang, Yongneng; Boukouris, Aristeidis E; Lorenzana Carrillo, Maria Areli; Jovel, Juan; Wagg, Cory S; Lopaschuk, Gary D; Michelakis, Evangelos D; Sutendra, Gopinath

Uncoupling of glycolysis from glucose oxidation accompanies the development of heart failure with preserved ejection fraction.

糖酵解与葡萄糖氧化脱钩是射血分数保留型心力衰竭发展过程中的伴随现象

Fillmore Natasha, Levasseur Jody L, Fukushima Arata, Wagg Cory S, Wang Wei, Dyck Jason R B, Lopaschuk Gary D

Chronic inhibition of pyruvate dehydrogenase in heart triggers an adaptive metabolic response

心脏中丙酮酸脱氢酶的慢性抑制会引发适应性代谢反应。

Chambers, Kari T; Leone, Teresa C; Sambandam, Nandakumar; Kovacs, Attila; Wagg, Cory S; Lopaschuk, Gary D; Finck, Brian N; Kelly, Daniel P

Diastolic dysfunction in familial hypertrophic cardiomyopathy transgenic model mice

家族性肥厚型心肌病转基因模型小鼠的舒张功能障碍

Abraham, Theodore P; Jones, Michelle; Kazmierczak, Katarzyna; Liang, Hsin-Yueh; Pinheiro, Aurelio C; Wagg, Cory S; Lopaschuk, Gary D; Szczesna-Cordary, Danuta