日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Combinations of approved oral nucleoside analogues confer potent suppression of alphaviruses in vitro and in vivo

已获批准的口服核苷类似物组合可在体外和体内有效抑制甲病毒。

Verwimp, Sam; Wagoner, Jessica; Arenas, Elijah Gabriela; De Coninck, Lander; Abdelnabi, Rana; Hyde, Jennifer L; Schiffer, Joshua T; White, Judith M; Matthijnssens, Jelle; Neyts, Johan; Polyak, Stephen J; Delang, Leen

A unifying model to explain frequent SARS-CoV-2 rebound after nirmatrelvir treatment and limited prophylactic efficacy

一个统一的模型可以解释尼尔马特雷韦治疗后SARS-CoV-2感染频繁反弹以及预防效果有限的现象。

Esmaeili, Shadisadat; Owens, Katherine; Wagoner, Jessica; Polyak, Stephen J; White, Judith M; Schiffer, Joshua T

A unifying model to explain high nirmatrelvir therapeutic efficacy against SARS-CoV-2, despite low post-exposure prophylaxis efficacy and frequent viral rebound

尽管暴露后预防效果低且病毒反弹频繁,但尼尔马特雷韦对SARS-CoV-2仍具有很高的治疗效果,这一现象可以通过统一模型来解释。

Esmaeili, Shadisadat; Owens, Katherine; Wagoner, Jessica; Polyak, Stephen J; White, Judith M; Schiffer, Joshua T

Combinations of Host- and Virus-Targeting Antiviral Drugs Confer Synergistic Suppression of SARS-CoV-2

宿主靶向抗病毒药物与病毒靶向抗病毒药物联合使用可协同抑制SARS-CoV-2病毒。

Wagoner, Jessica; Herring, Shawn; Hsiang, Tien-Ying; Ianevski, Aleksandr; Biering, Scott B; Xu, Shuang; Hoffmann, Markus; Pöhlmann, Stefan; Gale, Michael Jr; Aittokallio, Tero; Schiffer, Joshua T; White, Judith M; Polyak, Stephen J

Erratum for Herring et al., "Inhibition of Arenaviruses by Combinations of Orally Available Approved Drugs"

勘误表 Herring 等人,“口服批准药物组合对沙粒病毒的抑制”

Herring, Shawn; Oda, Jessica M; Wagoner, Jessica; Kirchmeier, Delaney; O'Connor, Aidan; Nelson, Elizabeth A; Huang, Qinfeng; Liang, Yuying; DeWald, Lisa Evans; Johansen, Lisa M; Glass, Pamela J; Olinger, Gene G; Ianevski, Aleksandr; Aittokallio, Tero; Paine, Mary F; Fink, Susan L; White, Judith M; Polyak, Stephen J

Central obesity is a contributor to systemic inflammation and monocyte activation in virally suppressed adults with chronic HIV in Kenya

在肯尼亚,中心性肥胖是慢性艾滋病毒感染且病毒载量受到抑制的成年患者出现全身炎症和单核细胞活化的因素之一。

Temu, Tecla M; Wagoner, Jessica; Masyuko, Sarah; O'Connor, Aidan; Zifodya, Jerry S; Macharia, Paul; Wanjalla, Celestine N; Mogaka, Jerusha N; Chohan, Bhavna; Omodi, Victor M; Gervassi, Ana L; Oyugi, Julius; Page, Stephanie T; Farquhar, Carey; Polyak, Stephen J

Antiretroviral therapy reduces but does not normalize immune and vascular inflammatory markers in adults with chronic HIV infection in Kenya

在肯尼亚,抗逆转录病毒疗法可以降低但不能使慢性艾滋病毒感染成年人的免疫和血管炎症标志物恢复正常。

Temu, Tecla M; Zifodya, Jerry S; Polyak, Stephen J; Wagoner, Jessica; Wanjalla, Celestine N; Masyuko, Sarah; Nyabiage, Jerusha; Kinuthia, John; Bloomfield, Gerald S; Page, Stephanie T; Farquhar, Carey

Uncovering biologically significant lipid isomers with liquid chromatography, ion mobility spectrometry and mass spectrometry

利用液相色谱、离子迁移谱和质谱法揭示具有生物学意义的脂质异构体

Kyle, Jennifer E; Zhang, Xing; Weitz, Karl K; Monroe, Matthew E; Ibrahim, Yehia M; Moore, Ronald J; Cha, Jeeyeon; Sun, Xiaofei; Lovelace, Erica S; Wagoner, Jessica; Polyak, Stephen J; Metz, Thomas O; Dey, Sudhansu K; Smith, Richard D; Burnum-Johnson, Kristin E; Baker, Erin S

Silymarin Suppresses Cellular Inflammation By Inducing Reparative Stress Signaling

水飞蓟素通过诱导修复性应激信号抑制细胞炎症

Lovelace, Erica S; Wagoner, Jessica; MacDonald, James; Bammler, Theo; Bruckner, Jacob; Brownell, Jessica; Beyer, Richard P; Zink, Erika M; Kim, Young-Mo; Kyle, Jennifer E; Webb-Robertson, Bobbie-Jo M; Waters, Katrina M; Metz, Thomas O; Farin, Federico; Oberlies, Nicholas H; Polyak, Stephen J

Differential in vitro effects of intravenous versus oral formulations of silibinin on the HCV life cycle and inflammation.

水飞蓟宾静脉注射制剂与口服制剂对HCV生命周期和炎症的体外差异性影响

Wagoner Jessica, Morishima Chihiro, Graf Tyler N, Oberlies Nicholas H, Teissier Elodie, Pécheur Eve-Isabelle, Tavis John E, Polyak Stephen J