日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Antigen reactivity defines tissue-resident memory and exhausted T cells in tumors

抗原反应性决定了肿瘤组织中组织驻留记忆T细胞和耗竭T细胞的存在。

Burn, Thomas N; Schröder, Jan; Gandolfo, Luke C; Osman, Maleika; Wainwright, Elanor N; Lam, Enid Y N; McDonald, Keely M; Evans, Rachel B; Li, Shihan; Rawlinson, Daniel; Dryburgh, Lachlan; Zaid, Ali; Maliga, Zoltan; Schienstock, Dominick; Meiser, Philippa; Lee, Hyun Jae; Lai, Hongjin; Moreira, Marcela L; Zareie, Pirooz; Lee, Louis H-Y; Huq, Lutfi; Christo, Susan N; Seow, Justine J W; Ching, Keith A; Guillaume, Stéphane M; Knezevic, Kathy; Park, Simone L; Evrard, Maximilien; Waithman, Jason; Gebhardt, Thomas; Mueller, Scott N; Riddiough, Georgina E; Perini, Marcos V; Tsao, Simon C H; Speed, Terence P; Sorger, Peter K; Loi, Sherene; Carbone, Francis R; Gras, Stephanie; Fisher, Timothy S; Baaten, Bas J; Dawson, Mark A; Mackay, Laura K

Flt3L-mediated tumor cDC1 expansion enhances immunotherapy by priming stem-like CD8(+) T cells in lymph nodes

Flt3L介导的肿瘤cDC1扩增通过启动淋巴结中的干细胞样CD8(+) T细胞来增强免疫疗法。

Lai, Junyun; Chan, Cheok Weng; Armitage, Jesse D; Audsley, Katherine M; Huang, Yu-Kuan; Derrick, Emily B; Carstensen, Laura S; Scheffler, Christina M; Jones, Matt E; Sek, Kevin; Principe, Nicola; Kim, Joelle S; House, Imran G; Chen, Amanda X Y; Yap, Kah Min; Middelburg, Jim; Munoz, Isabelle; Nguyen, Dat; Tong, Junming; Hoang, Thang X; Todd, Kirsten L; Evrard, Maximilien; Chee, Jonathan; Mackay, Laura K; Forrest, Alistair R R; Parish, Ian A; Bosco, Anthony; Waithman, Jason; Beavis, Paul A; Darcy, Phillip K

Comparative analysis of malignant pleural effusion and peripheral blood reveals unique T cell signatures associated with survival in mesothelioma patients

恶性胸腔积液和外周血的比较分析揭示了与间皮瘤患者生存相关的独特T细胞特征

Principe, Nicola; Stevens, Kofi L P; Phung, Amber-Lee; McCoy, Melanie; Kidman, Joel; Ismail, Ali; Cook, Alistair M; Chopra, Abha; Watson, Mark; Robinson, Bruce W; Creaney, Jenette; Lee, Y C Gary; Waithman, Jason; Lesterhuis, W Joost; Lake, Richard A; Nowak, Anna K; Chee, Jonathan; McDonnell, Alison M

Rewiring endogenous genes in CAR T cells for tumour-restricted payload delivery

通过重编程CAR T细胞中的内源基因,实现肿瘤特异性有效载荷递送。

Chen, Amanda X Y; Yap, Kah Min; Kim, Joelle S; Sek, Kevin; Huang, Yu-Kuan; Dunbar, Phoebe A; Wiebking, Volker; Armitage, Jesse D; Munoz, Isabelle; Todd, Kirsten L; Derrick, Emily B; Nguyen, Dat; Tong, Junming; Chan, Cheok Weng; Hoang, Thang X; Audsley, Katherine M; van Elsas, Marit J; Middelburg, Jim; Lee, Joel N; de Menezes, Maria N; Cole, Thomas J; Li, Jasmine; Scheffler, Christina; Scott, Andrew M; Mackay, Laura K; Waithman, Jason; Oliaro, Jane; Harrison, Simon J; Parish, Ian A; Lai, Junyun; Porteus, Matthew H; House, Imran G; Darcy, Phillip K; Beavis, Paul A

Tumor site-directed A1R expression enhances CAR T cell function and improves efficacy against solid tumors.

肿瘤部位定向的 A1R 表达可增强 CAR T 细胞功能,提高对实体瘤的疗效

Sek Kevin, Chen Amanda X Y, Cole Thomas, Armitage Jesse D, Tong Junming, Yap Kah Min, Munoz Isabelle, Dunbar Phoebe A, Wu Shiyi, van Elsas Marit J, Hidajat Olivia, Scheffler Christina, Giuffrida Lauren, Henderson Melissa A, Meyran Deborah, Souza-Fonseca-Guimaraes Fernando, Nguyen Dat, Huang Yu-Kuan, de Menezes Maria N, Derrick Emily B, Chan Cheok Weng, Todd Kirsten L, Chan Jack D, Li Jasmine, Lai Junyun, Petley Emma V, Mardiana Sherly, Bosco Anthony, Waithman Jason, Parish Ian A, Mølck Christina, Stewart Gregory D, Kats Lev, House Imran G, Darcy Phillip K, Beavis Paul A

Interleukin-4 modulates type I interferon to augment antitumor immunity.

白细胞介素-4调节I型干扰素,从而增强抗肿瘤免疫力

Newnes Hannah V, Armitage Jesse D, Buzzai Anthony C, de Jong Emma, Audsley Katherine M, Barnes Samantha A, Srinivasan Shamini, Serralha Michael, Fear Vanessa S, Guo Belinda B, Jones Matt E, Forrest Alistair R R, Foley Bree, Darcy Phil K, Beavis Paul A, Bosco Anthony, Waithman Jason

Antigen reactivity defines tissue-resident memory and exhausted T cells in tumours

抗原反应性定义了肿瘤组织中的组织驻留记忆T细胞和耗竭T细胞。

Burn, Thomas N; Schröder, Jan; Gandolfo, Luke C; Osman, Maleika; Wainwright, Elanor N; Lam, Enid Y N; McDonald, Keely M; Evans, Rachel B; Li, Shihan; Rawlinson, Daniel; Dryburgh, Lachlan; Zaid, Ali; Maliga, Zoltan; Schienstock, Dominick; Meiser, Philippa; Lee, Hyun Jae; Lai, Hongjin; Moreira, Marcela L; Zareie, Pirooz; Lee, Louis H-Y; Huq, Lutfi; Christo, Susan N; Seow, Justine J W; Ching, Keith A; Guillaume, Stéphane M; Knezevic, Kathy; Park, Simone L; Evrard, Maximilien; Waithman, Jason; Gebhardt, Thomas; Mueller, Scott N; Riddiough, Georgina E; Perini, Marcos V; Tsao, Simon C H; Speed, Terence P; Sorger, Peter K; Loi, Sherene; Carbone, Francis R; Gras, Stephanie; Fisher, Timothy S; Baaten, Bas J; Dawson, Mark A; Mackay, Laura K

Single cell transcriptomics reveals cell type specific features of developmentally regulated responses to lipopolysaccharide between birth and 5 years

单细胞转录组学揭示了出生至5岁期间发育调控的脂多糖反应的细胞类型特异性特征

Read, James F; Serralha, Michael; Armitage, Jesse D; Iqbal, Muhammad Munir; Cruickshank, Mark N; Saxena, Alka; Strickland, Deborah H; Waithman, Jason; Holt, Patrick G; Bosco, Anthony

Non-severe burn injury increases cancer incidence in mice and has long-term impacts on the activation and function of T cells

非重度烧伤会增加小鼠癌症的发生率,并对T细胞的激活和功能产生长期影响。

Barrett, Lucy W; Fear, Vanessa S; Foley, Bree; Audsley, Katherine; Barnes, Samantha; Newnes, Hannah; McDonnell, Alison; Wood, Fiona M; Fear, Mark W; Waithman, Jason

Tissue-resident memory T cells in the era of (Neo) adjuvant melanoma management

组织驻留记忆T细胞在(新)辅助黑色素瘤治疗时代的作用

Plunkett, Kai R; Armitage, Jesse D; Inderjeeth, Andrisha-Jade; McDonnell, Alison M; Waithman, Jason; Lau, Peter K H