日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

SMARCAL1 is a targetable synthetic lethal therapeutic vulnerability in ATRX-deficient gliomas that use Alternative Lengthening of Telomeres

SMARCAL1 是 ATRX 缺陷型胶质瘤中可靶向合成致死治疗的脆弱位点,这些胶质瘤利用端粒替代延长机制。

Brown, Alexandrea; Strickland, Laura M; Erman, Elise N; Pirozzi, Christopher J; Low, Justin T; Diplas, Bill H; Gibson, Emiley; Shobande, Mariah; Khambati, Taher; Krylova, Marharyta; Liu, Heng; McLendon, Roger E; Reitman, Zachary J; Keir, Stephen T; Zou, Lee; Ashley, David M; Waitkus, Matthew S

Antibiotic-Mediated Plasmonic-Mie Resonance for Biosensing Applications on a Novel Silicon Nanopillar Metasurface

抗生素介导的等离子体-米氏共振在新型硅纳米柱超表面上的生物传感应用中

Waitkus, Jacob; Park, JaeWoo; Ndukaife, Theodore; Yang, Sui; Du, Ke

Loss of function of Atrx recapitulates phenotypes of alternative lengthening of telomeres in a primary mouse model of sarcoma.

Atrx 功能丧失会在原发性小鼠肉瘤模型中重现端粒替代延长的表型

Pierpoint Matthew, Floyd Warren, Wisdom Amy J, Luo Lixia, Ma Yan, Dickson Brendan C, Waitkus Matthew S, Kirsch David G

Scarring Alopecia in Localized Dystrophic Epidermolysis Bullosa: A Case Report and a Scoping Review

局限性营养不良性大疱性表皮松解症并发瘢痕性脱发:病例报告及范围综述

Patra, Pratiksha; Ravichandran, Sairekha; Patel, Nishit; Rodriguez-Waitkus, Paul; Chen, Wei-Shen

Oncogenic Ppm1d mutations deregulate the p53 pathway in primary mouse gliomas

致癌性Ppm1d突变导致小鼠原发性神经胶质瘤中p53通路失调

Valentine, Vennesa; Groth, Abigail J; Tolliver, Joshua; Saravanapavan, Avneesh; Maingi, Spencer M; Weidenhammer, Loren B; Williams, Nerissa T; Luo, Lixia; Waitkus, Matthew S; Jacob, Sheeba; Reitman, Zachary J

Annular lesions in an HIV-positive male

HIV阳性男性患者的环状病变

Natarelli, Nicole; Myers, Elisha; Chen, Wei-Shen; Rodriguez-Waitkus, Paul

Interplay between ATRX and IDH1 mutations governs innate immune responses in diffuse gliomas

ATRX 和 IDH1 突变之间的相互作用调控弥漫性胶质瘤的先天免疫反应

Seethalakshmi Hariharan # ,Benjamin T Whitfield # ,Christopher J Pirozzi ,Matthew S Waitkus ,Michael C Brown ,Michelle L Bowie ,David M Irvin ,Kristen Roso ,Rebecca Fuller ,Janell Hostettler ,Sharvari Dharmaiah ,Emiley A Gibson ,Aaron Briley ,Avani Mangoli ,Casey Fraley ,Mariah Shobande ,Kevin Stevenson ,Gao Zhang ,Prit Benny Malgulwar ,Hannah Roberts ,Martin Roskoski ,Ivan Spasojevic ,Stephen T Keir ,Yiping He ,Maria G Castro ,Jason T Huse ,David M Ashley

Understanding and therapeutically exploiting cGAS/STING signaling in glioblastoma

了解并治疗性利用胶质母细胞瘤中的 cGAS/STING 信号通路

Low, Justin T; Brown, Michael C; Reitman, Zachary J; Bernstock, Joshua D; Markert, James M; Friedman, Gregory K; Waitkus, Matthew S; Bowie, Michelle L; Ashley, David M

Mechanisms of telomere maintenance and associated therapeutic vulnerabilities in malignant gliomas

恶性胶质瘤端粒维持机制及其相关治疗弱点

Waitkus, Matthew S; Erman, Elise N; Reitman, Zachary J; Ashley, David M

Cancer-associated SMARCAL1 loss-of-function mutations promote alternative lengthening of telomeres and tumorigenesis in telomerase-negative glioblastoma cells

癌症相关的 SMARCAL1 功能丧失突变促进端粒的替代延长和端粒酶阴性胶质母细胞瘤细胞中的肿瘤形成

Heng Liu, Cheng Xu, Bill H Diplas, Alexandrea Brown, Laura M Strickland, Haipei Yao, Jinjie Ling, Roger E McLendon, Stephen T Keir, David M Ashley, Yiping He, Matthew S Waitkus