SMARCAL1 is a targetable synthetic lethal therapeutic vulnerability in ATRX-deficient gliomas that use Alternative Lengthening of Telomeres
SMARCAL1 是 ATRX 缺陷型胶质瘤中可靶向合成致死治疗的脆弱位点,这些胶质瘤利用端粒替代延长机制。
期刊:Neuro-Oncology
影响因子:13.4
doi:10.1093/neuonc/noaf300
Brown, Alexandrea; Strickland, Laura M; Erman, Elise N; Pirozzi, Christopher J; Low, Justin T; Diplas, Bill H; Gibson, Emiley; Shobande, Mariah; Khambati, Taher; Krylova, Marharyta; Liu, Heng; McLendon, Roger E; Reitman, Zachary J; Keir, Stephen T; Zou, Lee; Ashley, David M; Waitkus, Matthew S