Complexation of Chol-DsiRNA in place of Chol-siRNA greatly increases the duration of mRNA suppression by polyplexes of PLL(30)-PEG(5K) in primary murine syngeneic breast tumors after i.v. administration
在静脉注射后，用 Chol-DsiRNA 代替 Chol-siRNA 形成复合物可显著延长 PLL(30)-PEG(5K) 多聚体对原发性小鼠同源乳腺肿瘤中 mRNA 抑制的持续时间。
期刊:International Journal of Pharmaceutics
影响因子:5.2
doi:10.1016/j.ijpharm.2018.03.045
Ambardekar, Vishakha V; Wakaskar, Rajesh R; Ye, Zhen; Curran, Stephen M; McGuire, Timothy R; Coulter, Don W; Singh, Rakesh K; Vetro, Joseph A
