日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Analysis and therapeutic targeting of the IL-1R pathway in anaplastic large cell lymphoma

间变性大细胞淋巴瘤中IL-1R通路分析及治疗靶向

Song, Zhihui; Wu, Wenjun; Wei, Wei; Xiao, Wenming; Lei, Michelle; Cai, Kathy Q; Huang, Da Wei; Jeong, Subin; Zhang, Jing-Ping; Wang, Hongbo; Kadin, Marshall E; Waldmann, Thomas A; Staudt, Louis M; Nakagawa, Masao; Yang, Yibin

Effective treatment with the selective cytokine inhibitor BNZ-1 reveals the cytokine dependency of T-LGL leukemia

使用选择性细胞因子抑制剂 BNZ-1 进行有效治疗揭示了 T-LGL 白血病对细胞因子的依赖性。

Brammer, Jonathan E; Ballen, Karen; Sokol, Lubomir; Querfeld, Christiane; Nakamura, Ryotaro; Mishra, Anjali; McLaughlin, Eric M; Feith, David; Azimi, Nazli; Waldmann, Thomas A; Tagaya, Yutaka; Loughran, Thomas

Interleukin-15 augments NK cell-mediated ADCC of alemtuzumab in patients with CD52+ T-cell malignancies

白细胞介素-15增强了CD52+ T细胞恶性肿瘤患者中阿仑单抗的NK细胞介导的ADCC作用

Miljkovic, Milos D; Dubois, Sigrid P; Müller, Jürgen R; Bryant, Bonita; Ma, Elaine; Conlon, Kevin C; Waldmann, Thomas A

Genome-wide CRISPR screen identifies CDK6 as a therapeutic target in adult T-cell leukemia/lymphoma

全基因组 CRISPR 筛选鉴定出 CDK6 为成人 T 细胞白血病/淋巴瘤的治疗靶点

Ishio, Takashi; Kumar, Sarvesh; Shimono, Joji; Daenthanasanmak, Anusara; Dubois, Sigrid; Lin, Yuquan; Bryant, Bonita; Petrus, Michael N; Bachy, Emmanuel; Huang, Da Wei; Yang, Yandan; Green, Patrick L; Hasegawa, Hiroo; Maeda, Michiyuki; Goto, Hideki; Endo, Tomoyuki; Yokota, Takashi; Hatanaka, Kanako C; Hatanaka, Yutaka; Tanaka, Shinya; Matsuno, Yoshihiro; Yang, Yibin; Hashino, Satoshi; Teshima, Takanori; Waldmann, Thomas A; Staudt, Louis M; Nakagawa, Masao

Genome-wide CRISPR screens identify CD48 defining susceptibility to NK cytotoxicity in peripheral T-cell lymphomas

全基因组 CRISPR 筛选发现 CD48 决定外周 T 细胞淋巴瘤对 NK 细胞毒性的易感性

Chiba, Masahiro; Shimono, Joji; Ishio, Takashi; Takei, Norio; Kasahara, Kohei; Ogasawara, Reiki; Ara, Takahide; Goto, Hideki; Izumiyama, Koh; Otsuguro, Satoko; Perera, Liyanage P; Hasegawa, Hiroo; Maeda, Michiyuki; Hashino, Satoshi; Maenaka, Katsumi; Teshima, Takanori; Waldmann, Thomas A; Yang, Yibin; Nakagawa, Masao

IL15 and Anti-PD-1 Augment the Efficacy of Agonistic Intratumoral Anti-CD40 in a Mouse Model with Multiple TRAMP-C2 Tumors

IL15 和抗 PD-1 可增强激动性瘤内注射抗 CD40 抗体在多发性 TRAMP-C2 肿瘤小鼠模型中的疗效

Chen, Wei; Bamford, Richard N; Edmondson, Elijah F; Waldmann, Thomas A

A novel model of alternative NF-κB pathway activation in anaplastic large cell lymphoma

间变性大细胞淋巴瘤中NF-κB通路替代激活的新模型

Wang, Hongbo; Wei, Wei; Zhang, Jing-Ping; Song, Zhihui; Li, Yangyang; Xiao, Wenming; Liu, Yijun; Zeng, Mu-Sheng; Petrus, Michael N; Thomas, Craig J; Kadin, Marshall E; Nakagawa, Masao; Waldmann, Thomas A; Yang, Yibin

Short-course IL-15 given as a continuous infusion led to a massive expansion of effective NK cells: implications for combination therapy with antitumor antibodies

短期持续输注IL-15可导致有效NK细胞大量扩增:对联合抗肿瘤抗体治疗的启示

Dubois, Sigrid P; Miljkovic, Milos D; Fleisher, Thomas A; Pittaluga, Stefania; Hsu-Albert, Jennifer; Bryant, Bonita R; Petrus, Michael N; Perera, Liyanage P; Müller, Jürgen R; Shih, Joanna H; Waldmann, Thomas A; Conlon, Kevin C

Phase I study of single agent NIZ985, a recombinant heterodimeric IL-15 agonist, in adult patients with metastatic or unresectable solid tumors

一项针对转移性或不可切除实体瘤成年患者的单药 NIZ985(一种重组异二聚体 IL-15 激动剂)的 I 期研究

Conlon, Kevin; Watson, Dionysios C; Waldmann, Thomas A; Valentin, Antonio; Bergamaschi, Cristina; Felber, Barbara K; Peer, Cody J; Figg, William D; Potter, E Lake; Roederer, Mario; McNeel, Douglas G; Thompson, John A; Gupta, Sumati; Leidner, Rom; Wang-Gillam, Andrea; Parikh, Nehal S; Long, Debby; Kurtulus, Sema; Ho Lee, Lang; Chowdhury, Niladri Roy; Bender, Florent; Pavlakis, George N

NF-κB-induced R-loop accumulation and DNA damage select for nucleotide excision repair deficiencies in adult T cell leukemia.

NF-κB 诱导的 R 环积累和 DNA 损伤导致成人 T 细胞白血病中核苷酸切除修复缺陷

He Yunlong, Pasupala Nagesh, Zhi Huijun, Dorjbal Batsuhk, Hussain Imran, Shih Hsiu-Ming, Bhattacharyya Sharmistha, Biswas Roopa, Miljkovic Milos, Semmes Oliver John, Waldmann Thomas A, Snow Andrew L, Giam Chou-Zen