A(2A)R antagonist IDPU facilitates the restoration of mitochondrial dynamics in 6-OHDA-induced primary mid-brain neuronal cells, via regulating p38MAPK/Parkin/DJ-1/DRP1 axis.
A(2A)R拮抗剂IDPU通过调节p38MAPK/Parkin/DJ-1/DRP1轴，促进6-OHDA诱导的原代中脑神经元细胞线粒体动力学的恢复。
期刊:Purinergic Signalling
影响因子:2.4
doi:10.1007/s11302-025-10124-4
Walecha Vaishali, Mishra Jyoti, Sophronea Tuithung, Kumari Namrata, Luthra Pratibha Mehta
DRP1
神经科学
MAPK/ERK
线粒体
Parkin
细胞生物学
DJ-1
