日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Characterization and validation of a spontaneous acute and protracted oxycodone withdrawal model in male and female mice

对雄性和雌性小鼠自发性急性及慢性羟考酮戒断模型进行表征和验证

Contreras, Katherine M; Buzzi, Belle; Vaughn, Julian; Caillaud, Martial; Altarifi, Ahmad A; Olszewski, Emily; Walentiny, D Matthew; Beardsley, Patrick M; Damaj, M Imad

Enantiomeric contributions to methamphetamine's bidirectional effects on basal and fentanyl-depressed respiration in mice

对映体在甲基苯丙胺对小鼠基础呼吸和芬太尼抑制呼吸的双向作用中的贡献

Elder, Harrison J; Walentiny, D Matthew; Beardsley, Patrick M

Nelotanserin, a selective 5-HT2A receptor inverse agonist, attenuates aspects of nicotine withdrawal but not reward in mice

选择性5-HT2A受体反向激动剂奈洛坦色林可减轻小鼠尼古丁戒断症状的某些方面,但对奖赏效应无影响。

Buzzi, Belle; AlSharari, Shakir D; Walentiny, David M; Damaj, M Imad

Theophylline reverses oxycodone's but not fentanyl's respiratory depression in mice while caffeine is ineffective against both opioids

茶碱可逆转小鼠的羟可酮呼吸抑制,但不能逆转芬太尼的呼吸抑制,而咖啡因对这两种阿片类药物均无效

Harrison J Elder, D Matthew Walentiny, Patrick M Beardsley

Structurally diverse fentanyl analogs yield differential locomotor activities in mice

结构多样的芬太尼类似物在小鼠中产生不同的运动活动

Neil B Varshneya, D Matthew Walentiny, David L Stevens, Teneille D Walker, Luli R Akinfiresoye, Patrick M Beardsley

NLX-112, a highly selective 5-HT(1A) receptor biased agonist, does not exhibit misuse potential in male rats or macaques

NLX-112 是一种高选择性的 5-HT(1A) 受体偏向性激动剂,在雄性大鼠或猕猴中未表现出滥用潜力。

Depoortère, R; Bergman, J; Beardsley, P M; Desai, R I; Paronis, C A; Walentiny, D M; Varney, M A; Newman-Tancredi, A

Methylnaltrexone crosses the blood-brain barrier and attenuates centrally-mediated behavioral effects of morphine and oxycodone in mice

甲基纳曲酮穿过血脑屏障并减弱小鼠吗啡和羟可酮的中枢介导行为效应

D Matthew Walentiny, Essie Komla, Léa T Moisa, Mohammed A Mustafa, Justin L Poklis, Hamid I Akbarali, Patrick M Beardsley

Fentanyl-related substances elicit antinociception and hyperlocomotion in mice via opioid receptors

芬太尼相关物质通过阿片受体引起小鼠抗伤害和运动亢进

Neil B Varshneya, D Matthew Walentiny, Lea T Moisa, Teneille D Walker, Luli R Akinfiresoye, Patrick M Beardsley

Opioid-like antinociceptive and locomotor effects of emerging fentanyl-related substances

新兴芬太尼相关物质的阿片类镇痛和运动作用

Neil B Varshneya, D Matthew Walentiny, Lea T Moisa, Teneille D Walker, Luli R Akinfiresoye, Patrick M Beardsley

Pharmacological characterization of 17-cyclopropylmethyl-3,14-dihydroxy-4,5-epoxy-6-[(3'-fluoro-4'-pyridyl)acetamido]morphinan (NFP) as a dual selective MOR/KOR ligand with potential applications in treating opioid use disorder

17-环丙基甲基-3,14-二羟基-4,5-环氧-6-[(3'-氟-4'-吡啶基)乙酰氨基]吗啡喃 (NFP) 作为双选择性 MOR/KOR 配体的药理学表征及其在治疗阿片类药物使用障碍中的潜在应用

Yi Zheng, Samuel Obeng, Bethany A Reinecke, Chongguang Chen, Palak S Phansalkar, David M Walentiny, Phillip M Gerk, Lee-Yuan Liu-Chen, Dana E Selley, Patrick M Beardsley, Yan Zhang