日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Virtual Screening for the Discovery of Microbiome β-Glucuronidase Inhibitors to Alleviate Cancer Drug Toxicity.

利用虚拟筛选发现微生物组β-葡萄糖醛酸酶抑制剂以减轻癌症药物毒性

Challa Anup P, Hu Xin, Zhang Ya-Qin, Hymes Jeffrey, Wallace Bret D, Karavadhi Surendra, Sun Hongmao, Patnaik Samarjit, Hall Matthew D, Shen Min

Targeted inhibition of gut bacterial β-glucuronidase activity enhances anticancer drug efficacy

靶向抑制肠道细菌β-葡萄糖醛酸酶活性可增强抗癌药物疗效

Bhatt, Aadra P; Pellock, Samuel J; Biernat, Kristen A; Walton, William G; Wallace, Bret D; Creekmore, Benjamin C; Letertre, Marine M; Swann, Jonathan R; Wilson, Ian D; Roques, Jose R; Darr, David B; Bailey, Sean T; Montgomery, Stephanie A; Roach, Jeffrey M; Azcarate-Peril, M Andrea; Sartor, R Balfour; Gharaibeh, Raad Z; Bultman, Scott J; Redinbo, Matthew R

Structure of the sirtuin-linked macrodomain SAV0325 from Staphylococcus aureus

金黄色葡萄球菌中sirtuin连接宏结构域SAV0325的结构

Appel, C Denise; Feld, Geoffrey K; Wallace, Bret D; Williams, R Scott

Recognition and repair of chemically heterogeneous structures at DNA ends

识别和修复DNA末端的化学异质结构

Andres, Sara N; Schellenberg, Matthew J; Wallace, Bret D; Tumbale, Percy; Williams, R Scott

Structure and Inhibition of Microbiome β-Glucuronidases Essential to the Alleviation of Cancer Drug Toxicity

微生物组β-葡萄糖醛酸酶的结构和抑制对于缓解癌症药物毒性至关重要

Wallace, Bret D; Roberts, Adam B; Pollet, Rebecca M; Ingle, James D; Biernat, Kristen A; Pellock, Samuel J; Venkatesh, Madhu Kumar; Guthrie, Leah; O'Neal, Sara K; Robinson, Sara J; Dollinger, Makani; Figueroa, Esteban; McShane, Sarah R; Cohen, Rachel D; Jin, Jian; Frye, Stephen V; Zamboni, William C; Pepe-Ranney, Charles; Mani, Sridhar; Kelly, Libusha; Redinbo, Matthew R

Ribonucleotide triggered DNA damage and RNA-DNA damage responses

核糖核苷酸引发的DNA损伤和RNA-DNA损伤反应

Wallace, Bret D; Williams, R Scott

The human microbiome is a source of therapeutic drug targets

人类微生物组是治疗药物靶点的来源。

Wallace, Bret D; Redinbo, Matthew R