日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

panTB-HM: a multi-arm clinical trial of a pan-TB regimen targeting both host and microbe

panTB-HM:一项针对宿主和微生物的泛结核病治疗方案的多臂临床试验

Mudzengi, D; Mashatole, S; Xiang, Q; Adrion, C; Glover, N; Ngwanto, T; Mdluli, J; Boniface, S; Rassool, M; Matome, B; Paramo, L; Svensson, E; Fasanmi, A; Angelo, S; Moyo, M; Marx, C; Khosa, C; Mokaba, L; Mofokeng, N; Lalashowi, J; Nacy, C; Charalambous, S; Fumane, E; Maphossa, V; Beattie, T; Brumskine, W; Venter, C; Mapamba, D; Heinrich, N; Rajaram, S; Kooverjee, S; Botha, L; Nell, M; Easton, A; Foraida, S; Warren, Robin Mark; Sabi, Issa; Ntinginya, N; Wallis, R S

Mycobacterium avium complex (MAC) elimination slopes from sputum are potential treatment response biomarkers in patients with HIV and pulmonary MAC

痰液中鸟分枝杆菌复合群(MAC)的清除斜率是HIV合并肺部MAC患者潜在的治疗反应生物标志物。

Pasipanodya, J G; Nqwata, L; Schmitz, J; Srivastava, S; Wanjalla, C N; Wallis, R S; Dooley, K E

Neuromyelitis optica causing vision loss during TB treatment with sutezolid: evidence of aberrant immunity following infection

结核病患者在接受苏特唑胺治疗期间发生视神经脊髓炎,导致视力丧失:感染后免疫异常的证据

Glover, N A; Paramo, L; Giangregorio, S; Sukwana, B; Koele, S E; Charalambous, S; Ngwanto, T; Mashatole, S; Mudzengi, D; Heinrich, N; Svensson, E M; Abdullah, F; Churchyard, G; Wallis, R S

Perspectives from the 2(nd) International Post-Tuberculosis Symposium: mobilising advocacy and research for improved outcomes

第二届国际结核病后遗症研讨会的展望:动员倡导和研究以改善预后

Allwood, B W; Nightingale, R; Agbota, G; Auld, S; Bisson, G P; Byrne, A; Dunn, R; Evans, D; Hoddinott, G; Günther, G; Islam, Z; Johnston, J C; Kalyatanda, G; Khosa, C; Marais, S; Makanda, G; Mashedi, O M; Meghji, J; Mitnick, C; Mulder, C; Nkereuwem, E; Nkereuwem, O; Ozoh, O B; Rachow, A; Romanowski, K; Seddon, J A; Schoeman, I; Thienemann, F; Walker, N F; Wademan, D T; Wallis, R; van der Zalm, M M

Performance of spirometry assessment at TB diagnosis

结核病诊断时肺功能测定评估的性能

Rachow, A; Ivanova, O; Bakuli, A; Khosa, C; Nhassengo, P; Owolabi, O; Jayasooriya, S; Ntinginya, N E; Sabi, I; Rassool, M; Bennet, J; Niemann, S; Mekota, A-M; Allwood, B W; Wallis, R S; Charalambous, S; Hoelscher, M; Churchyard, G

A phase IIb, open-label, randomized controlled dose ranging multi-centre trial to evaluate the safety, tolerability, pharmacokinetics and exposure-response relationship of different doses of delpazolid in combination with bedaquiline delamanid moxifloxacin in adult subjects with newly diagnosed, uncomplicated, smear-positive, drug-sensitive pulmonary tuberculosis

一项 IIb 期、开放标签、随机对照、剂量范围多中心试验,旨在评估不同剂量的德尔帕唑利联合贝达喹啉、德拉马尼和莫西沙星治疗新诊断的、无并发症的、涂片阳性、药物敏感性肺结核成年患者的安全性、耐受性、药代动力学和暴露-反应关系。

Dierig, A; Hoelscher, M; Schultz, S; Hoffmann, L; Jarchow-MacDonald, A; Svensson, E M; Te Brake, L; Aarnoutse, R; Boeree, M; McHugh, T D; Wildner, L M; Gong, X; Phillips, Ppj; Minja, L T; Ntinginya, N; Mpagama, S; Liyoyo, A; Wallis, R S; Sebe, M; Mhimbira, F A; Mbeya, B; Rassool, M; Geiter, L; Cho, Y L; Heinrich, N

Clinical standards for the assessment, management and rehabilitation of post-TB lung disease

结核病后肺病的评估、管理和康复的临床标准

Migliori, G B; Marx, F M; Ambrosino, N; Zampogna, E; Schaaf, H S; van der Zalm, M M; Allwood, B; Byrne, A L; Mortimer, K; Wallis, R S; Fox, G J; Leung, C C; Chakaya, J M; Seaworth, B; Rachow, A; Marais, B J; Furin, J; Akkerman, O W; Al Yaquobi, F; Amaral, A F S; Borisov, S; Caminero, J A; Carvalho, A C C; Chesov, D; Codecasa, L R; Teixeira, R C; Dalcolmo, M P; Datta, S; Dinh-Xuan, A-T; Duarte, R; Evans, C A; García-García, J-M; Günther, G; Hoddinott, G; Huddart, S; Ivanova, O; Laniado-Laborín, R; Manga, S; Manika, K; Mariandyshev, A; Mello, F C Q; Mpagama, S G; Muñoz-Torrico, M; Nahid, P; Ong, C W M; Palmero, D J; Piubello, A; Pontali, E; Silva, D R; Singla, R; Spanevello, A; Tiberi, S; Udwadia, Z F; Vitacca, M; Centis, R; D Ambrosio, L; Sotgiu, G; Lange, C; Visca, D

Mutations that improve efficiency of a weak-link enzyme are rare compared to adaptive mutations elsewhere in the genome

与基因组其他地方的适应性突变相比,提高弱连接酶效率的突变非常罕见

Andrew B Morgenthaler, Wallis R Kinney, Christopher C Ebmeier, Corinne M Walsh, Daniel J Snyder, Vaughn S Cooper, William M Old, Shelley D Copley

Mannan binding lectin-associated serine protease 1 is induced by hepatitis C virus infection and activates human hepatic stellate cells.

丙型肝炎病毒感染可诱导甘露聚糖结合凝集素相关丝氨酸蛋白酶 1 的表达,并激活人肝星状细胞

Saeed A, Baloch K, Brown R J P, Wallis R, Chen L, Dexter L, McClure C P, Shakesheff K, Thomson B J

How can we improve our understanding of cardiovascular safety liabilities to develop safer medicines?

我们如何才能更好地了解心血管安全隐患,从而研发出更安全的药物?

Laverty, Hg; Benson, C; Cartwright, Ej; Cross, Mj; Garland, C; Hammond, T; Holloway, C; McMahon, N; Milligan, J; Park, Bk; Pirmohamed, M; Pollard, C; Radford, J; Roome, N; Sager, P; Singh, S; Suter, T; Suter, W; Trafford, A; Volders, Pga; Wallis, R; Weaver, R; York, M; Valentin, Jp