日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Mutant knock-in mice display enhanced susceptibility to pure prion protein fibrils

基因敲入突变小鼠对纯朊病毒蛋白原纤维表现出更高的易感性

Walsh, Daniel J; Standke, Heidi; Kraus, Allison; Watts, Joel C; Supattapone, Surachai

Development, characterization, and curve fitting of rate-dependent models of calcified cerebral embolus analogs for acute ischemic stroke

急性缺血性卒中钙化脑栓塞类似物速率依赖性模型的开发、表征和曲线拟合

Monclova, Jose L; Walsh, Daniel J; Hummel, Madelyn E; Weatherwax, Sophia; Costanzo, Francesco; Simon, Scott D; Manning, Keefe B

A hyper-viscoelastic uniaxial characterization of collagenous embolus analogs in acute ischemic stroke

急性缺血性卒中中胶原栓塞类似物的超粘弹性单轴表征

Monclova, Jose L; Walsh, Daniel J; Barraclough, Terrell; Hummel, Madelyn E; Goetz, Ian; Kannojiya, Vikas; Costanzo, Francesco; Simon, Scott D; Manning, Keefe B

Conformational diversity in purified prions produced in vitro

体外产生的纯化朊病毒的构象多样性

Walsh, Daniel J; Schwind, Abigail M; Noble, Geoffrey P; Supattapone, Surachai

Anti-prion drugs do not improve survival in knock-in models of inherited prion disease

抗朊病毒药物并不能提高遗传性朊病毒病基因敲入模型的生存率。

Walsh, Daniel J; Rees, Judy R; Mehra, Surabhi; Bourkas, Matthew E C; Kaczmarczyk, Lech; Stuart, Erica; Jackson, Walker S; Watts, Joel C; Supattapone, Surachai

Cofactor and glycosylation preferences for in vitro prion conversion are predominantly determined by strain conformation

体外朊病毒转化所需的辅因子和糖基化偏好主要由毒株构象决定。

Burke, Cassandra M; Walsh, Daniel J; Mark, Kenneth M K; Deleault, Nathan R; Nishina, Koren A; Agrimi, Umberto; Di Bari, Michele A; Supattapone, Surachai

Mutations that improve efficiency of a weak-link enzyme are rare compared to adaptive mutations elsewhere in the genome

与基因组其他地方的适应性突变相比,提高弱连接酶效率的突变非常罕见

Andrew B Morgenthaler, Wallis R Kinney, Christopher C Ebmeier, Corinne M Walsh, Daniel J Snyder, Vaughn S Cooper, William M Old, Shelley D Copley

Full restoration of specific infectivity and strain properties from pure mammalian prion protein

完全恢复纯哺乳动物朊病毒蛋白的特异性感染性和毒株特性

Burke, Cassandra M; Walsh, Daniel J; Steele, Alexander D; Agrimi, Umberto; Di Bari, Michele Angelo; Watts, Joel C; Supattapone, Surachai

Non-reducing alkaline solubilization and rapid on-column refolding of recombinant prion protein.

重组朊病毒蛋白的非还原性碱性溶解和柱上快速复性

Walsh Daniel J, Noble Geoffrey P, Piro Justin R, Supattapone Surachai