日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Binding between Crossveinless-2 and Chordin von Willebrand factor type C domains promotes BMP signaling by blocking Chordin activity

Crossveinless-2 与 Chordin von Willebrand 因子 C 型结构域之间的结合通过阻断 Chordin 活性来促进 BMP 信号传导

Jin-Li Zhang, Lucy J Patterson, Li-Yan Qiu, Daria Graziussi, Walter Sebald, Matthias Hammerschmidt

A selection fit mechanism in BMP receptor IA as a possible source for BMP ligand-receptor promiscuity

BMP 受体 IA 中的选择契合机制可能是 BMP 配体-受体混杂性的可能来源

Stefan Harth, Alexander Kotzsch, Junli Hu, Walter Sebald, Thomas D Mueller

Receptor oligomerization and beyond: a case study in bone morphogenetic proteins

受体寡聚化及其他:骨形态发生蛋白的案例研究

Kai Heinecke, Axel Seher, Werner Schmitz, Thomas D Mueller, Walter Sebald, Joachim Nickel

Mutations in GDF5 reveal a key residue mediating BMP inhibition by NOGGIN

GDF5 突变揭示了 NOGGIN 介导 BMP 抑制的关键残基

Petra Seemann, Anja Brehm, Jana König, Carsten Reissner, Sigmar Stricker, Pia Kuss, Julia Haupt, Stephanie Renninger, Joachim Nickel, Walter Sebald, Jay C Groppe, Frank Plöger, Jens Pohl, Mareen Schmidt-von Kegler, Maria Walther, Ingmar Gassner, Cristina Rusu, Andreas R Janecke, Katarina Dathe, Stef

Crystallization and preliminary X-ray analysis of the complex of the first von Willebrand type C domain bound to bone morphogenetic protein 2

第一个冯·威勒布兰德 C 型结构域与骨形态发生蛋白 2 结合的复合物的结晶和初步 X 射线分析

Li-yan Qiu, Jin-li Zhang, Alexander Kotzsch, Walter Sebald, Thomas D Mueller

A silent H-bond can be mutationally activated for high-affinity interaction of BMP-2 and activin type IIB receptor

沉默的氢键可以通过突变激活,从而实现 BMP-2 和激活素 IIB 型受体的高亲和力相互作用

Dionys Weber, Alexander Kotzsch, Joachim Nickel, Stefan Harth, Axel Seher, Uwe Mueller, Walter Sebald, Thomas D Mueller

Enthalpic and entropic contributions mediate the role of disulfide bonds on the conformational stability of interleukin-4

焓和熵贡献介导二硫键对白细胞介素-4 构象稳定性的作用

Daniela C Vaz, J Rui Rodrigues, Walter Sebald, Christopher M Dobson, Rui M M Brito

A modular interface of IL-4 allows for scalable affinity without affecting specificity for the IL-4 receptor

IL-4 的模块化接口可实现可扩展的亲和力,而不会影响 IL-4 受体的特异性

Michael Kraich, Markus Klein, Edwin Patiño, Henning Harrer, Joachim Nickel, Walter Sebald, Thomas D Mueller

Activating and deactivating mutations in the receptor interaction site of GDF5 cause symphalangism or brachydactyly type A2

GDF5 受体相互作用位点的激活和失活突变会导致 A2 型指关节畸形或短指畸形

Petra Seemann, Raphaela Schwappacher, Klaus W Kjaer, Deborah Krakow, Katarina Lehmann, Katherine Dawson, Sigmar Stricker, Jens Pohl, Frank Plöger, Eike Staub, Joachim Nickel, Walter Sebald, Petra Knaus, Stefan Mundlos