日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

MscM uses a novel gating mechanism for bacterial mechanosensitive channels

MscM采用了一种新型的细菌机械敏感通道门控机制

Hiotis, Giorgos; Walz, Thomas

Lipid interactions and gating hysteresis suggest a physiological role for mechanosensitive channel YnaI

脂质相互作用和门控滞后现象表明机械敏感通道YnaI具有生理功能。

Will, Nathan; Hiotis, Giorgos; Nakayama, Yoshitaka; Angiulli, Gabriella; Zhou, Zijing; Cox, Charles D; Martinac, Boris; Walz, Thomas

An αIIbβ3 ligand-mimetic murine monoclonal antibody that produces platelet activation by engaging the FcγIIa receptor

一种αIIbβ3配体模拟鼠单克隆抗体,可通过与FcγIIa受体结合而激活血小板。

Wang, Jialing; Buitrago, Lorena; Wang, Lu; Li, Jihong; Walz, Thomas; Coller, Barry S

Nanodiscs remain indispensable for Cryo-EM studies of membrane proteins

纳米盘对于膜蛋白的冷冻电镜研究仍然不可或缺。

Hiotis, Giorgos; Notti, Ryan Q; Bao, Huan; Walz, Thomas

POT1 recruits and regulates CST-Polα/primase at human telomeres.

POT1 在人类端粒处招募和调节 CST-Polα/引物酶

Cai Sarah W, Takai Hiroyuki, Zaug Arthur J, Dilgen Teague C, Cech Thomas R, Walz Thomas, de Lange Titia

An αIIbβ3 monoclonal antibody traps a semiextended conformation and allosterically inhibits large ligand binding

αIIbβ3单克隆抗体可捕获半伸展构象,并通过变构作用抑制大分子配体的结合。

Wang, Lu; Wang, Jialing; Li, Jihong; Walz, Thomas; Coller, Barry S

Structure and dynamics of cholesterol-mediated aquaporin-0 arrays and implications for lipid rafts

胆固醇介导的水通道蛋白-0阵列的结构和动力学及其对脂筏的影响

Chiu, Po-Lin; Orjuela, Juan D; de Groot, Bert L; Aponte Santamaría, Camilo; Walz, Thomas

Native-like environments afford novel mechanistic insights into membrane proteins

类似天然环境的研究为深入了解膜蛋白的机制提供了新的视角。

Notti, Ryan Q; Walz, Thomas

Shelterin is a dimeric complex with extensive structural heterogeneity

Shelterin 是一种具有广泛结构异质性的二聚体复合物。

Zinder, John C; Olinares, Paul Dominic B; Svetlov, Vladimir; Bush, Martin W; Nudler, Evgeny; Chait, Brian T; Walz, Thomas; de Lange, Titia

Structure-Based Discovery of a Novel Class of Small-Molecule Pure Antagonists of Integrin αVβ3.

基于结构的新型小分子纯整合素αVβ3拮抗剂的发现

Sen Soumyo, Spasic Aleksandar, Sinha Anjana, Wang Jialing, Bush Martin, Li Jihong, Nešić Dragana, Zhou Yuchen, Angiulli Gabriella, Morgan Paul, Salas-Estrada Leslie, Takagi Junichi, Walz Thomas, Coller Barry S, Filizola Marta