日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Precise excision of expanded GGC repeats in NOTCH2NLC via CRISPR/Cas9 for treating neuronal intranuclear inclusion disease.

利用 CRISPR/Cas9 技术精确切除 NOTCH2NLC 中扩增的 GGC 重复序列，用于治疗神经元核内包涵体病。

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-026-68385-5
Xie Nina, Pan Yongcheng, Tong Huichun, Lin Yingqi, Jiang Ying, Wang Zhiqin, Wan Juan, Zhang Wendiao, Wang Xinhui, Sun Xiaobo, Yan Sen, Yin Peng, Sun Qiying, Qi Chengzhi, Tian Yun, Shen Lu, Jiang Hong, Liang Desheng, Tang Beisha, Li Shihua, Li Xiao-Jiang, Liu Qiong
神经科学
OTC
CAS9
NOTCH
Notch
发表日期：2026
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TRIM56 Aggravates Cerebral Ischemia-Reperfusion Injury via Inhibiting KLF4-Activated Ferroptosis Signaling.

TRIM56 通过抑制 KLF4 激活的铁死亡信号通路加剧脑缺血再灌注损伤。

期刊:Advanced Science
影响因子:14.1
doi:10.1002/advs.202509906
Wang Qiangping, Li Shuang, Li Man, Zhou Wenke, Zhang Jianqing, Wu Zhenfu, Mao Zhaoqi, Wan Juan, Tang Xinhao, Zheng Baoping, Liu Qiang, Li Zhendong, Jiang Xiaobing, Wu Qingping, Ye Youfan, Wang Haijun
信号转导
KLF4
铁死亡
发表日期：2026
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The anti-NMDAR1 antibodies and IL-17 signaling pathway shape NMDAR encephalitis

抗NMDAR1抗体和IL-17信号通路在NMDAR脑炎中发挥作用

期刊:Molecular Psychiatry
影响因子:10.1
doi:10.1038/s41380-025-03434-x
Xu, Zhenhong; Yan, Hongye; Wang, Bo; Wan, Juan; Wang, Huimin; Xia, Ye; Liu, Yong U; Wang, Xuejing; Wu, Heng; Jiang, Jiamei; Zeng, Lin; Tang, Beisha; Meng, Qingtuan
信号转导
脑炎
神经科学
IL-17
发表日期：2026
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Targeted next-generation sequencing for comprehensive diagnosis and drug resistance detection in pulmonary and extrapulmonary tuberculosis: a single-center retrospective study

靶向二代测序技术在肺结核和肺外结核的全面诊断和耐药性检测中的应用：一项单中心回顾性研究

期刊:Microbiology Spectrum
影响因子:3.8
doi:10.1128/spectrum.01698-25
Dai, Jingyi; Li, Qiujing; Wan, Juan; Sun, Fengshuo; Zhou, Gang; Yang, Meiqiu; Dong, Chuanshu; Fang, Yao; Li, Lifeng; Wang, Lin; Liu, Guiming
微生物学
Sequencing
肺结核
发表日期：2026
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IFN-γ and IL-6 as Key Predicting Biomarkers for Active TB Among PLWH: Results from Four Machine Learning Methods

IFN-γ 和 IL-6 作为 HIV 感染者活动性结核病的关键预测生物标志物：四种机器学习方法的结果

期刊:International Journal of General Medicine
影响因子:2
doi:10.2147/IJGM.S572335
Wan, Juan; Chongsuvivatwong, Virasakdi; Zhang, Pei; Li, Qiujing; Zhao, Liping; Zou, Lingqing; Zhao, Jun; Dai, Jingyi
HIV
炎症/感染
微生物学
IFN-γ
IL-6
发表日期：2026
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Complete chloroplast genome analysis of Polygala chinensis L. (= P. glomerata Lour.) (Fabales, Polygalaceae)

中华远志（Polygala chinensis L. (= P. glomerata Lour.) (Fabales, Polygalaceae)）的完整叶绿体基因组分析

期刊:Mitochondrial Dna Part B-Resources
影响因子:0.7
doi:10.1080/23802359.2026.2617765
Chen, Chao; Lan, Pin; Fang, Yuan-Hua; Lai, Lin-Jie; Chen, Jie; Liu, Wan-Juan
发表日期：2026
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Integrated screening identifies GPR31 as a key driver and druggable target for metabolic dysfunction-associated steatohepatitis.

综合筛查发现 GPR31 是代谢功能障碍相关脂肪性肝炎的关键驱动因素和可药物靶点

期刊:Journal of Clinical Investigation
影响因子:13.6
doi:10.1172/JCI173193
Zhang Xiao-Jing, Fu Jiajun, Cheng Xu, Shen Hong, Yang Hailong, Wang Kun, Li Wei, Tian Han, Tian Tian, Zhou Junjie, Tian Song, Wang Zhouxiang, Wan Juan, Bai Lan, Duan Hongfei, Zhang Xin, Tian Ruifeng, Xu Haibo, Liao Rufang, Zou Toujun, Shi Jing, Qu Weiyi, Fang Liang, Cai Jingjing, Zhang Peng, She Zhi-Gang, Jiang Jingwei, Hu Yufeng, Wang Yibin, Li Hongliang
代谢
肝炎
炎症
发表日期：2025
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HnRNP M expression rescues neurodegeneration in neuronal intranuclear inclusion disease mouse model by restoring dysregulated RNA splicing and transcription.

HnRNP M 表达通过恢复失调的 RNA 剪接和转录来挽救神经元核内包涵体病小鼠模型中的神经退行性变

期刊:Cell and Bioscience
影响因子:6.2
doi:10.1186/s13578-025-01477-9
Pan Yongcheng, Li Yangping, Jiang Ying, Wang Xinhui, Wan Juan, Sun Qiying, Tian Yun, Shen Lu, Jiang Hong, Tang Beisha, Yao Bing, Liu Qiong
神经科学
Mouse
发表日期：2025
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The ADCY1-mediated cAMP signaling pathway mediates functional effects of montelukast treatment in brain organoids.

ADCY1介导的cAMP信号通路介导孟鲁司特治疗对脑类器官的功能性影响

期刊:Cellular and Molecular Life Sciences
影响因子:6.2
doi:10.1007/s00018-025-05764-z
Xu Zhenhong, Yan Hongye, Wang Bo, Wang Huimin, Xia Ye, Wan Juan, Jiang Jiamei, Zeng Lin, Tang Beisha, Meng Qingtuan
信号转导
3D/类器官
发表日期：2025
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Ras homolog enriched in brain 1 regulates β cell mass and β cell function via mTORC1/AMPK/Notch1 pathways.

脑内富集的 Ras 同源物 1 通过 mTORC1/AMPK/Notch1 通路调节 β 细胞质量和 β 细胞功能

期刊:World Journal of Diabetes
影响因子:4.6
doi:10.4239/wjd.v16.i6.104973
Yang Yan, Song Wan-Juan, Zhang Jing-Jing
细胞生物学
AMPK
Notch
mTOR
发表日期：2025
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