Hirudin suppresses hematogenous metastasis by targeting desmosome junction transition in circulating tumor cell clusters via HIF-1α-DSG2 signaling
水蛭素通过HIF-1α-DSG2信号通路靶向循环肿瘤细胞簇中的桥粒连接转变，从而抑制血行转移。
期刊:Experimental and Molecular Medicine
影响因子:12.9
doi:10.1038/s12276-025-01598-8
Zou, Jueyao; Shi, Junfeng; Chen, Qiong; Zhu, Ziyan; Hu, Tongyao; Zhang, Zhengyu; Pan, Zhiqiang; Xu, Fei; Zhu, Yong; Wu, Yuanyuan; Zhao, Yang; Wang, Aiyun; Lu, Yin; Pan, Yanhong; Chen, Wenxing
