Wang Caiyan相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

Forsythoside E Alleviates Liver Injury by Targeting PKM2 Tetramerization to Promote Macrophage M2 Polarization

连翘苷E通过靶向PKM2四聚体化促进巨噬细胞M2极化，从而减轻肝损伤

期刊:Advanced Science

影响因子:14.1

doi:10.1002/advs.202514514

Wu, Bingxin; Yu, Xuechun; Li, Yanling; An, Lin; Zhang, Rongrong; Zhang, Rong; Zhang, Fan; Liu, Zhongqiu; Wang, Caiyan

细胞生物学

免疫/内分泌

发表日期：2026

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Schisandrin B Targets PXR to Enhance Bile Acid Metabolism and Alleviate ANIT-Induced Cholestatic Liver Injury via Dual Pathways

五味子素B通过双重途径靶向PXR，增强胆汁酸代谢并减轻ANIT诱导的胆汁淤积性肝损伤

期刊:International Journal of Biological Sciences

影响因子:10

doi:10.7150/ijbs.121475

Zhang, Ying; Lan, Huan; Yu, Xuechun; Zhuo, Lin; Zhao, Bixin; Liu, Fang; An, Lin; Zhang, Fan; Liu, Zhongqiu; Wang, Caiyan

发表日期：2026

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Structural pharmacology of Chinese medicine: technological breakthroughs in decoding multi-target synergy and precision mechanisms

中药结构药理学：解码多靶点协同作用和精准机制的技术突破

doi:10.1007/s44307-026-00095-x

Wang, Caiyan; Li, Yanling; Zhuo, Lin; Xu, Songzhu; Wang, Mengyao; Liu, Zhongqiu

发表日期：2026

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Advances in pharmacological interventions for hepatic fibrosis: from pathogenic mechanisms to novel therapeutic targets

肝纤维化药物干预的进展：从致病机制到新型治疗靶点

doi:10.1080/07853890.2026.2613502

Zhang, Weiqin; Shao, Ting; Wang, Caiyan; Wang, Shaogui; An, Lin

发表日期：2026

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A high-κ homogeneous ink for printable electroluminescent devices

一种用于可印刷电致发光器件的高介电常数均质油墨

期刊:Nature Communications

影响因子:15.7

doi:10.1038/s41467-025-64075-w

Li, Tao; Li, Zhengwen; Chen, Weilong; Chen, Junhao; Zhou, Haijie; Wang, Caiyan; Cao, Xiaochun; Li, Bin; Ding, Shujiang; Shi, Lei

发表日期：2025

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Geniposidic Acid Targeting FXR "S332 and H447" Mediated Conformational Change to Upregulate CYPs and miR-19a-3p to Ameliorate Drug-Induced Liver Injury.

京尼泊苷酸靶向 FXR“S332 和 H447”介导的构象变化，上调 CYP 和 miR-19a-3p，从而改善药物引起的肝损伤

期刊:Advanced Science

影响因子:14.1

doi:10.1002/advs.202409107

Fan Minqi, Xu Yuanhang, Wu Bingxin, Long Jiachan, Liu Caihong, Liang Zuhui, Zhang Rong, Liu Zhongqiu, Wang Caiyan

发表日期：2025

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Caffeic acid alleviates myocardial ischemia-reperfusion injury by directly targeting Keap1(N532/M550) and promoting its degradation.

咖啡酸通过直接靶向 Keap1(N532/M550) 并促进其降解来减轻心肌缺血再灌注损伤。

期刊:Journal of Pharmaceutical Analysis

影响因子:8.9

doi:10.1016/j.jpha.2025.101219

Zhang Ying, Lan Huan, Zhai Wenjuan, Jiang Lin, Xia Xiaotong, Liu Fang, Zhang Lin, Wu Jinjun, Liu Zhongqiu, Wang Caiyan

发表日期：2025

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Malat1 regulates PMN-MDSC expansion and immunosuppression through p-STAT3 ubiquitination in sepsis

Malat1 通过 p-STAT3 泛素化调节脓毒症中的 PMN-MDSC 扩增和免疫抑制

期刊:International Journal of Biological Sciences

影响因子:8.2

doi:10.7150/ijbs.92267

Yaodong Wang, Caiyan Zhang, Tingyan Liu, Zhenhao Yu, Kexin Wang, Jiayun Ying, Yao Wang, Ting Zhu, Jingjing Li, Xiuchuan Lucas Hu, Yufeng Zhou, Guoping Lu

发表日期：2024

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IRGM/Irgm1 increases autophagy to inhibit activation of NLRP3 inflammasome in inflammatory injury induced acute liver failure

IRGM/Irgm1 增加自噬以抑制炎症损伤引起的急性肝衰竭中 NLRP3 炎症小体的激活

期刊:Cell Death Discovery

影响因子:6.1

doi:10.1038/s41420-024-02052-w

Xing Zhang #, Yangyang Hu #, Wei Wang, Ru Ji, Ziyue Li, Weiyan Yu, Zhinian Wu, Ying Xiao, Tingyu Guo, Zeqiang Qi, Yadong Wang, Caiyan Zhao

细胞生物学

发表日期：2024

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Three bioactive compounds from Huangqin decoction ameliorate Irinotecan-induced diarrhea via dual-targeting of Escherichia coli and bacterial Î²-glucuronidase.

黄芩汤中的三种生物活性化合物通过双重靶向大肠杆菌和细菌β-葡糖醛酸酶来改善伊立替康引起的腹泻

期刊:Cell Biology and Toxicology

影响因子:5.9

doi:10.1007/s10565-024-09922-0

Teng Xiaojun, Wu Bingxin, Liang Zuhui, Zhang Lisheng, Yang Maolin, Liu Zhongqiu, Liang Qi, Wang Caiyan

发表日期：2024

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