ALDH4A1 functions as an active component of the MPC complex maintaining mitochondrial pyruvate import for TCA cycle entry and tumour suppression.
ALDH4A1 作为 MPC 复合物的活性成分，维持线粒体丙酮酸的输入，从而进入 TCA 循环并抑制肿瘤生长
期刊:Nature Cell Biology
影响因子:19.1
doi:10.1038/s41556-025-01651-8
Hsu Che-Chia, Wang Chi-Yun, Manne Rajesh Kumar, Cai Zhen, Penugurti Vasudevarao, Kant Rajni, Bai Ling, Pan Bo-Syong, Chen Tingjin, Chen Yuan-Ru, Wu Hsin-En, Jin Yan, Gu Haiwei, Li Chia-Yang, Lin Hui-Kuan
