ISGylation of γH2AX retains MDC1 and facilitates homologous recombination repair causing radioresistance in esophageal adenocarcinoma
γH2AX 的 ISGylation 可保留 MDC1 并促进同源重组修复,从而导致食管腺癌的放射抗性。
期刊:Journal of Biological Chemistry
影响因子:3.9
doi:10.1016/j.jbc.2026.111358
Ghosh, Archismaan; Ray, Paramita; Thomas, Dafydd; Jeeyar, Vinay; Pillai, Shreya; Basrur, Venkatesha; Bondarenko, Irina V; Bellile, Emily; Wang, David H; Morgan, Meredith A; Zhang, Qiang; Beer, David G; Lagisetty, Kiran H; Lawrence, Theodore S; Ray, Dipankar