Wang Gang Greg相关文献与解析，生知库 | 链接生命科学的每一步

Li Dongxu, Zhang Zhi-Min, Mei Liu, Yu Yao, Guo Yiran, Mackintosh Samuel G, Chen Jianbin, Allison David F, Kim Arum, Storey Aaron J, Edmondson Ricky D, Byrum Stephanie D, Tackett Alan J, Cai Ling, Cook Jeanette G, Song Jikui, Wang Gang Greg

其它

发表日期：2025

文献求助收藏

Pharmacologic degradation of WDR5 suppresses oncogenic activities of SS18::SSX and provides a therapeutic of synovial sarcoma.

WDR5 的药理降解可抑制 SS18::SSX 的致癌活性，并为滑膜肉瘤的治疗提供可能

期刊:Science Advances

影响因子:12.5

doi:10.1126/sciadv.ads7876

Yu Yao, Yu Xufen, Pan Bo, Chan Ho Man, Kaniskan H Ãmit, Jin Jian, Cai Ling, Wang Gang Greg

Multiple transactivation domains of EZH2 bind to the TAZ2 domain of p300 and stimulate the acetyltransferase function of p300.

EZH2 的多个转录激活结构域与 p300 的 TAZ2 结构域结合，并刺激 p300 的乙酰转移酶功能

期刊:Biochemical Journal

影响因子:4.3

doi:10.1042/BCJ20253037

Becht Dustin C, Biswas Soumi, Xu Chenxi, Xuan Hongwen, Khalil Moustafa, Cai Ling, Musselman Catherine A, Liu Xin, Affar El Bachir, Shi Xiaobing, Wang Gang Greg, Kutateladze Tatiana G

免疫/内分泌

发表日期：2025

文献求助收藏

Written in chromatin: The enduring legacy of C. David Allis

染色质上的文字：C·大卫·艾利斯的永恒遗产

期刊:Journal of Biological Chemistry

影响因子:3.9

doi:10.1016/j.jbc.2025.110240

Strahl, Brian D; Wang, Gang Greg

发表日期：2025

文献求助收藏

The sotos syndrome gene Nsd1 safeguards developmental gene enhancers poised for transcription by maintaining the precise deposition of histone methylation.

Sotos 综合征基因 Nsd1 通过维持组蛋白甲基化的精确沉积来保护准备转录的发育基因增强子

期刊:Journal of Biological Chemistry

影响因子:3.9

doi:10.1016/j.jbc.2025.108423

Li Jie, Li Zhucui, Yin Jiekai, Wang Yinsheng, Zheng Deyou, Cai Ling, Wang Gang Greg

Stress-induced loss of CTCF reveals an alternative, promoter-based mode of cohesin looping.

应激诱导的 CTCF 丢失揭示了一种替代的、基于启动子的黏连蛋白环化模式。

期刊:

影响因子:

doi:10.64898/2025.12.19.695003

Flores J P, Perreault Andrea A, Drum Zack, Xu Chenxi, Alonso Doris Cruz, Petros Gelila, Wu Yijia, Quiroga-Barber Ivana Y, Kim HyunAh, Sahasrabudhe Isha, Demmerle Justin, Wang Gang Greg, Cai Danfeng, Phanstiel Douglas H

CTCF

发表日期：2025

文献求助收藏

Structural basis for the H2AK119ub1-specific DNMT3A-nucleosome interaction

H2AK119ub1 特异性 DNMT3A-核小体相互作用的结构基础

期刊:Nature Communications

影响因子:14.7

doi:10.1038/s41467-024-50526-3

Xinyi Chen #, Yiran Guo #, Ting Zhao, Jiuwei Lu, Jian Fang, Yinsheng Wang, Gang Greg Wang, Jikui Song

信号转导

发表日期：2024

文献求助收藏

Structure-guided functional suppression of AML-associated DNMT3A hotspot mutations

结构导向的AML相关DNMT3A热点突变的功能抑制

期刊:Nature Communications

影响因子:14.7

doi:10.1038/s41467-024-47398-y.

Jiuwei Lu # ,Yiran Guo # ,Jiekai Yin ,Jianbin Chen ,Yinsheng Wang ,Gang Greg Wang ,Jikui Song

Onco-condensates: formation, multi-component organization, and biological functions

肿瘤凝聚体：形成、多组分结构和生物学功能

期刊:Trends in Cancer

影响因子:17.5

doi:10.1016/j.trecan.2023.05.006

Xu, Chenxi; Kim, Arum; Corbin, Joshua M; Wang, Gang Greg

A Unified Model: Chromatin-Bound Multicomponent Condensates

统一模型：染色质结合的多组分凝聚体

BAHCC1 binds H4K20me1 to facilitate the MCM complex loading and DNA replication.

BAHCC1 与 H4K20me1 结合，促进 MCM 复合物的加载和 DNA 复制

Pharmacologic degradation of WDR5 suppresses oncogenic activities of SS18::SSX and provides a therapeutic of synovial sarcoma.

WDR5 的药理降解可抑制 SS18::SSX 的致癌活性，并为滑膜肉瘤的治疗提供可能

Multiple transactivation domains of EZH2 bind to the TAZ2 domain of p300 and stimulate the acetyltransferase function of p300.

EZH2 的多个转录激活结构域与 p300 的 TAZ2 结构域结合，并刺激 p300 的乙酰转移酶功能

Written in chromatin: The enduring legacy of C. David Allis

染色质上的文字：C·大卫·艾利斯的永恒遗产

The sotos syndrome gene Nsd1 safeguards developmental gene enhancers poised for transcription by maintaining the precise deposition of histone methylation.

Sotos 综合征基因 Nsd1 通过维持组蛋白甲基化的精确沉积来保护准备转录的发育基因增强子

Stress-induced loss of CTCF reveals an alternative, promoter-based mode of cohesin looping.

应激诱导的 CTCF 丢失揭示了一种替代的、基于启动子的黏连蛋白环化模式。

Structural basis for the H2AK119ub1-specific DNMT3A-nucleosome interaction

H2AK119ub1 特异性 DNMT3A-核小体相互作用的结构基础

Structure-guided functional suppression of AML-associated DNMT3A hotspot mutations

结构导向的AML相关DNMT3A热点突变的功能抑制

Onco-condensates: formation, multi-component organization, and biological functions

肿瘤凝聚体：形成、多组分结构和生物学功能