文献库，生知库 | 链接生命科学的每一步

Long Non-Coding RNA IGFRIL Couples with PTBP1 to Destabilize IGFBP3 mRNA to Promote the IGF1R-AKT-mTOR Axis and Hepatocellular Carcinoma.

长链非编码RNA IGFRIL与PTBP1结合，使IGFBP3 mRNA不稳定，从而促进IGF1R-AKT-mTOR轴和肝细胞癌的发生。

doi:10.1002/advs.202507676

Zhang Jing, Gao Chengming, Li Haibei, Chen Yuying, Yang Liting, Jin Qian, Feng Lan, Wang Xia, Liu Xinyi, Chen Hongxia, Ye Rong, Xue Yuanchao, Wang Huiyun, Zeng Musheng, Yang Ming, Ju Huaiqiang, Gao Chengzhi, Zhou Guangming, Zhang Qi, Zhang Qian, Qin Geng, Li Yuanfeng, Wang Yahui, Yang Aiqing, Si Anfeng, Song Qingfeng, He Fuchu, Cao Pengbo, Zhou Gangqiao

MicroRNA-24-3p targeting Top1 in perirenal fat is involved in circulating inflammation and high cardiovascular disease risk in patients with primary aldosteronism

肾周脂肪组织中靶向 Top1 的 microRNA-24-3p 与原发性醛固酮增多症患者的循环炎症和高心血管疾病风险有关。

期刊:Journal of Translational Medicine

影响因子:7.5

doi:10.1186/s12967-025-06329-1

Li, Xuelin; Luo, Min; Zeng, Yanmei; Zhang, Renyi; Lin, Xiaochun; Du, Yuejun; Zhao, Wei; Feng, Qijian; Wu, Minghai; Zhang, Jin; Guo, Lei; Wu, Peili; Yang, Chuyi; Cai, Feifei; Wang, Yuan; Hu, Yuxuan; Wang, Huiyun; Liu, Nannan; Xu, Lingling; Guan, Meiping

Reduced expression of UPF1 promotes tumor progression through stabilizing COX-2 mRNA in nasopharyngeal carcinoma

UPF1表达降低通过稳定鼻咽癌中的COX-2 mRNA促进肿瘤进展

期刊:Frontiers in Immunology

影响因子:5.9

doi:10.3389/fimmu.2025.1617864

Wu, Chun; Xiao, Ruowen; Zhang, Lin; Chen, Zixuan; Zhang, Meiyin; Li, Jiaxin; Zhou, Yufeng; Wang, Shuocheng; Jiang, Chao; Wang, Huiyun; Sun, Rui; Mai, Shijuan

Additions of trastuzumab to preoperative chemotherapy or chemoimmunotherapy for patients with potentially resectable stage III to IV(B) HER2-positive gastric cancer

对于潜在可切除的III期至IV(B)期HER2阳性胃癌患者，在术前化疗或化疗免疫疗法中加入曲妥珠单抗治疗

期刊:Frontiers in Immunology

影响因子:5.9

doi:10.3389/fimmu.2025.1624943

Zhang, Xuchen; Tian, Yulong; Wang, Huiyun; Song, Shanai; Chen, Yunqing; Liu, Ning; Zhang, Chuantao; Huang, Xiao; Jiang, Haitao; Hou, Helei

Holistic Molecular Design of Ionic Surfaces for Tailored Water Wettability and Technical Applications

离子表面的整体分子设计及其在定制水润湿性和技术应用中的应用

期刊:Nanomaterials

影响因子:4.3

doi:10.3390/nano15080591

Wang, Huiyun; Cheng, Chongling; Wang, Dayang

发表日期：2025

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Asiatic Acid Alleviates Renal Damage by Upregulating STBD1-Mediated Glycophagy in Diabetic Kidney Disease

积雪草酸通过上调STBD1介导的糖自噬作用减轻糖尿病肾病中的肾损伤

期刊:Biomedicines

影响因子:3.9

doi:10.3390/biomedicines13071544

Guo, Lei; Wu, Peili; Feng, Qijian; Lin, Xiaochun; Wang, Yuan; Wu, Minghai; Cai, Feifei; Zhang, Jin; Yang, Chuyi; Li, Xuelin; Wen, Churan; Lin, Yingbei; Liu, Nannan; Hu, Yuxuan; Wang, Huiyun; Fan, Xinzhao; Guan, Meiping

Next-generation sequencing identifies potential mechanisms of primary resistance to trastuzumab-containing therapies in HER2-positive gastric cancer: Analysis based on real-world data and online databases

新一代测序技术揭示了HER2阳性胃癌对含曲妥珠单抗疗法产生原发性耐药的潜在机制：基于真实世界数据和在线数据库的分析

期刊:Human Vaccines & Immunotherapeutics

影响因子:3.5

doi:10.1080/21645515.2025.2555502

Zhang, Xuchen; Liu, Ning; Song, Shanai; Zhang, Chuantao; Li, Tianjun; Song, Wei; Huang, Shusheng; Chen, Yunqing; Yan, Weihua; Zhan, Jinfeng; Wang, Huiyun; Cui, Jiali; Jiang, Man; Hou, Helei

A case report: Achieving complete response in synchronous primary lung and tongue squamous cell carcinomas through the integration of albumin-bound paclitaxel, cisplatin, and tislelizumab

病例报告：通过整合白蛋白结合型紫杉醇、顺铂和替雷利珠单抗治疗同步原发性肺癌和舌鳞状细胞癌，实现完全缓解

期刊:Human Vaccines & Immunotherapeutics

影响因子:3.5

doi:10.1080/21645515.2025.2593104

Huang, Xiao; Ma, Ying; Wang, Huiyun; Song, Shanai; Li, Tianjun; Zhang, Chuantao; Hou, Helei

Efficacy and safety of neoadjuvant treatment with chemotherapy and immune checkpoint blockades for potentially resectable gastric cancer: A retrospective study

新辅助化疗联合免疫检查点阻断治疗潜在可切除胃癌的疗效和安全性：一项回顾性研究

期刊:Human Vaccines & Immunotherapeutics

影响因子:3.5

doi:10.1080/21645515.2025.2550096

Wang, Huiyun; Zhang, Xuchen; Tian, Yulong; Jiang, Haitao; Liu, Ning; Zhan, Jinfeng; Chen, Yunqing; Song, Shanai; Huang, Xiao; Jiang, Man; Zhang, Chuantao; Hou, Helei

A versatile self-cleaning fabric coating as a detergent-free laundry product

一种用途广泛的自清洁织物涂层，可用作无洗涤剂洗衣产品

Long Non-Coding RNA IGFRIL Couples with PTBP1 to Destabilize IGFBP3 mRNA to Promote the IGF1R-AKT-mTOR Axis and Hepatocellular Carcinoma.

长链非编码RNA IGFRIL与PTBP1结合，使IGFBP3 mRNA不稳定，从而促进IGF1R-AKT-mTOR轴和肝细胞癌的发生。

MicroRNA-24-3p targeting Top1 in perirenal fat is involved in circulating inflammation and high cardiovascular disease risk in patients with primary aldosteronism

肾周脂肪组织中靶向 Top1 的 microRNA-24-3p 与原发性醛固酮增多症患者的循环炎症和高心血管疾病风险有关。

Reduced expression of UPF1 promotes tumor progression through stabilizing COX-2 mRNA in nasopharyngeal carcinoma

UPF1表达降低通过稳定鼻咽癌中的COX-2 mRNA促进肿瘤进展

Additions of trastuzumab to preoperative chemotherapy or chemoimmunotherapy for patients with potentially resectable stage III to IV(B) HER2-positive gastric cancer

对于潜在可切除的III期至IV(B)期HER2阳性胃癌患者，在术前化疗或化疗免疫疗法中加入曲妥珠单抗治疗

Holistic Molecular Design of Ionic Surfaces for Tailored Water Wettability and Technical Applications

离子表面的整体分子设计及其在定制水润湿性和技术应用中的应用

Asiatic Acid Alleviates Renal Damage by Upregulating STBD1-Mediated Glycophagy in Diabetic Kidney Disease

积雪草酸通过上调STBD1介导的糖自噬作用减轻糖尿病肾病中的肾损伤

Next-generation sequencing identifies potential mechanisms of primary resistance to trastuzumab-containing therapies in HER2-positive gastric cancer: Analysis based on real-world data and online databases

新一代测序技术揭示了HER2阳性胃癌对含曲妥珠单抗疗法产生原发性耐药的潜在机制：基于真实世界数据和在线数据库的分析

A case report: Achieving complete response in synchronous primary lung and tongue squamous cell carcinomas through the integration of albumin-bound paclitaxel, cisplatin, and tislelizumab

病例报告：通过整合白蛋白结合型紫杉醇、顺铂和替雷利珠单抗治疗同步原发性肺癌和舌鳞状细胞癌，实现完全缓解

Efficacy and safety of neoadjuvant treatment with chemotherapy and immune checkpoint blockades for potentially resectable gastric cancer: A retrospective study

新辅助化疗联合免疫检查点阻断治疗潜在可切除胃癌的疗效和安全性：一项回顾性研究