日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Pre-existing TCR clones drive major pathological responses in HNSCC patients treated with dual immune checkpoint inhibitors

预先存在的TCR克隆驱动接受双重免疫检查点抑制剂治疗的头颈部鳞状细胞癌患者发生主要的病理反应。

Ge, Huaibin; Li, Housaiyin; Kulkarni, Aditi; Chen, Zhangguo; Upadhyay, Pragati; Ferris, Robert L; Wang, Jing H

Integrated Transcriptomic and Single-Cell Analyses Identify HILPDA as a Hypoxia-Mediated Regulator of Ferroptotic Signaling in Glioblastoma

整合转录组学和单细胞分析表明,HILPDA 是胶质母细胞瘤中缺氧介导的铁死亡信号通路调节因子

Liu, Zeyu; John, Jessy; Johnson, Nickolas; Singh, Priya; Wang, Ziyi; Sanchez, Gilson J; Simons, Dylan; Wang, Jing H; Liu, Xuedong; Hacioglu, Nelin

MHC class I upregulation contributes to the therapeutic response to radiotherapy in combination with anti-PD-L1/anti-TGF-β in squamous cell carcinomas with enhanced CD8 T cell memory-driven response.

MHC I 类上调有助于增强 CD8 T 细胞记忆驱动反应的鳞状细胞癌对放射疗法联合抗 PD-L1/抗 TGF-β 疗法的治疗反应

Lind Hanne T, Hall Spencer C, Strait Alexander A, Goon Jack B, Aleman John D, Chen Samantha M Y, Karam Sana D, Young Christian D, Wang Jing H, Wang Xiao-Jing

Targeting Myeloid Cells in Head and Neck Squamous Cell Carcinoma: A Kinase Inhibitor Library Screening Approach

靶向头颈部鳞状细胞癌中的髓系细胞:激酶抑制剂库筛选方法

Zaky, Mohamed Y; John, Jessy; Vashisht, Monika; Singh, Priya; Al-Hatamleh, Mohammad A I; Siddoway, Karen; Chen, Zhangguo; Wang, Jing H

Th2 Cells Are Associated with Tumor Recurrence Following Radiation

Th2细胞与放射治疗后肿瘤复发相关

Abdelhakiem, Mohamed K; Bao, Riyue; Pifer, Phillip M; Molkentine, David; Molkentine, Jessica; Hefner, Andrew; Beadle, Beth; Heymach, John V; Luke, Jason J; Ferris, Robert L; Pickering, Curtis R; Wang, Jing H; Patel, Ravi B; Skinner, Heath D

Cetuximab Responses in Patients with HNSCC Correlate to Clonal Expansion Feature of Peripheral and Tumor-Infiltrating T Cells with Top T-Cell Receptor Clonotypes

西妥昔单抗治疗头颈部鳞状细胞癌患者的疗效与外周血和肿瘤浸润T细胞的克隆扩增特征以及主要T细胞受体克隆型相关

Ge, Huaibin; Ferris, Robert L; Wang, Jing H

Differential responses to immune checkpoint inhibitor dictated by pre-existing differential immune profiles in squamous cell carcinomas caused by same initial oncogenic drivers

由相同初始致癌驱动因子引起的鳞状细胞癌中,预先存在的不同免疫特征决定了其对免疫检查点抑制剂的不同反应。

Samantha M Y Chen ,Vince Popolizio ,Rachel A Woolaver ,Huaibin Ge ,Alexandra L Krinsky ,Jessy John ,Etienne Danis ,Yao Ke ,Yonatan Kramer ,Li Bian ,Andrew G Nicklawsky ,Dexiang Gao ,Silvia Liu ,Zhangguo Chen ,Xiao-Jing Wang ,Jing H Wang

Why responses to immune checkpoint inhibitors are heterogeneous in head and neck cancers: Contributions from tumor-intrinsic and host-intrinsic factors

头颈癌患者对免疫检查点抑制剂的反应为何存在异质性:肿瘤内在因素和宿主内在因素的影响

Chen, Zhangguo; John, Jessy; Wang, Jing H

MHC class I-independent activation of virtual memory CD8 T cells induced by chemotherapeutic agent-treated cancer cells

化疗药物处理的癌细胞诱导的虚拟记忆CD8 T细胞的MHC I类非依赖性激活

Wang, Xiaoguang; Waschke, Brittany C; Woolaver, Rachel A; Chen, Samantha M Y; Chen, Zhangguo; Wang, Jing H

How the Signaling Crosstalk of B Cell Receptor (BCR) and Co-Receptors Regulates Antibody Class Switch Recombination: A New Perspective of Checkpoints of BCR Signaling

B细胞受体(BCR)及其辅助受体的信号串扰如何调控抗体类别转换重组:BCR信号检查点的新视角

Chen, Zhangguo; Wang, Jing H