Wang Jue D相关文献与解析，生知库 | 链接生命科学的每一步

Zheng, Liujuan; Young, Megan K M; Steinchen, Wieland; Guo, Zhiyong; Jalomo-Khayrova, Ekaterina; Liu, Bobby Xuanyu; Burchert, Fabiana; Bedrunka, Patricia; Mais, Christopher-Nils; Pané-Farré, Jan; Girbig, Mathias; Linne, Uwe; Trinquier, Aude; Li, Aitao; Hochberg, Georg; Freitag, Johannes; Wang, Jue D; Bange, Gert

信号转导

乙酰化

表观遗传

发表日期：2026

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Starvation-independent alarmone production inhibits translation through GTP depletion

不依赖于饥饿的报警素产生通过消耗GTP抑制翻译

期刊:

影响因子:

doi:10.64898/2026.01.12.699007

England, Kevin A; Trinquier, Aude; McKinney, Leah K; Wang, Jue D; Feaga, Heather A

发表日期：2026

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A shared alarmone-GTP switch controls persister formation in bacteria

细菌中一种共享的报警素-GTP开关控制着持久菌的形成

期刊:Nature Microbiology

影响因子:19.4

doi:10.1038/s41564-025-02015-6

Fung, Danny K; Barra, Jessica T; Yang, Jin; Schroeder, Jeremy W; She, Fukang; Young, Megan; Ying, David; Stevenson, David M; Amador-Noguez, Daniel; Wang, Jue D

微生物学

发表日期：2025

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Pyruvate kinase directly generates GTP in glycolysis, supporting growth and contributing to guanosine toxicity

丙酮酸激酶在糖酵解过程中直接生成GTP，促进细胞生长并导致鸟苷毒性。

期刊:mBio

影响因子:4.7

doi:10.1128/mbio.03798-24

She, Fukang; Liu, Kuanqing; Anderson, Brent W; Pisithkul, Tippapha; Li, Yanxiu; Fung, Danny K; McCue, Tyler; Mulhern, William; Amador-Noguez, Daniel; Wang, Jue D

Allosteric regulation of pyruvate kinase enables efficient and robust gluconeogenesis by preventing metabolic conflicts and carbon overflow

丙酮酸激酶的变构调节通过防止代谢冲突和碳过载，实现高效且稳健的糖异生。

期刊:mSystems

影响因子:4.6

doi:10.1128/msystems.01131-24

She, Fukang; Anderson, Brent W; Khana, Daven B; Zhang, Shenwei; Steinchen, Wieland; Fung, Danny K; Lesser, Nathalie G; Lucas, Lauren N; Stevenson, David M; Astmann, Theresa J; Bange, Gert; van Pijkeren, Jan-Peter; Amador-Noguez, Daniel; Wang, Jue D

From dusty shelves toward the spotlight: growing evidence for Ap4A as an alarmone in maintaining RNA stability and proteostasis

从尘封的书架走向聚光灯下：越来越多的证据表明 Ap4A 是一种维持 RNA 稳定性和蛋白质稳态的报警分子

期刊:Current Opinion in Microbiology

影响因子:7.5

doi:10.1016/j.mib.2024.102536

Young, Megan Km; Wang, Jue D

蛋白质稳态

发表日期：2024

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The τ of alarmone hydrolysis

报警素水解的τ

期刊:Nature Chemical Biology

影响因子:13.7

doi:10.1038/s41589-022-01200-6

Fung, Danny K; Wang, Jue D

发表日期：2023

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Mitochondrial GTP metabolism controls reproductive aging in C.Â elegans.

线粒体 GTP 代谢控制秀丽隐杆线虫的生殖衰老

期刊:Developmental Cell

影响因子:8.7

doi:10.1016/j.devcel.2023.08.019

Lee Yi-Tang, Savini Marzia, Chen Tao, Yang Jin, Zhao Qian, Ding Lang, Gao Shihong Max, Senturk Mumine, Sowa Jessica N, Wang Jue D, Wang Meng C

Crosstalk between (p)ppGpp and other nucleotide second messengers

(p)ppGpp 与其他核苷酸第二信使之间的串扰

期刊:Current Opinion in Microbiology

影响因子:7.5

doi:10.1016/j.mib.2023.102398

Fung, Danny K; Trinquier, Aude E; Wang, Jue D

信号转导

发表日期：2023

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Mitochondrial GTP Metabolism Regulates Reproductive Aging

线粒体GTP代谢调控生殖衰老

期刊:

影响因子:

doi:10.1101/2023.04.02.535296

Lee, Yi-Tang; Savini, Marzia; Chen, Tao; Yang, Jin; Zhao, Qian; Ding, Lang; Gao, Shihong Max; Senturk, Mumine; Sowa, Jessica; Wang, Jue D; Wang, Meng C

A protein adaptor mediating Ap4A-dependent control of protein acetylation

一种介导 Ap4A 依赖性蛋白质乙酰化调控的蛋白质衔接蛋白

Starvation-independent alarmone production inhibits translation through GTP depletion

不依赖于饥饿的报警素产生通过消耗GTP抑制翻译

A shared alarmone-GTP switch controls persister formation in bacteria

细菌中一种共享的报警素-GTP开关控制着持久菌的形成

Pyruvate kinase directly generates GTP in glycolysis, supporting growth and contributing to guanosine toxicity

丙酮酸激酶在糖酵解过程中直接生成GTP，促进细胞生长并导致鸟苷毒性。

Allosteric regulation of pyruvate kinase enables efficient and robust gluconeogenesis by preventing metabolic conflicts and carbon overflow

丙酮酸激酶的变构调节通过防止代谢冲突和碳过载，实现高效且稳健的糖异生。

From dusty shelves toward the spotlight: growing evidence for Ap4A as an alarmone in maintaining RNA stability and proteostasis

从尘封的书架走向聚光灯下：越来越多的证据表明 Ap4A 是一种维持 RNA 稳定性和蛋白质稳态的报警分子

The τ of alarmone hydrolysis

报警素水解的τ

Mitochondrial GTP metabolism controls reproductive aging in C.Â elegans.

线粒体 GTP 代谢控制秀丽隐杆线虫的生殖衰老

Crosstalk between (p)ppGpp and other nucleotide second messengers

(p)ppGpp 与其他核苷酸第二信使之间的串扰

Mitochondrial GTP Metabolism Regulates Reproductive Aging

线粒体GTP代谢调控生殖衰老