Oncolytic virus OH2 induces PD-L1 upregulation via NF-κB signaling and synergizes with anti-PD-L1 therapy in prostate cancer through a targeted extracellular vesicle delivery system
溶瘤病毒OH2通过NF-κB信号通路诱导PD-L1上调，并通过靶向细胞外囊泡递送系统与抗PD-L1疗法在治疗前列腺癌中发挥协同作用。
期刊:Journal for ImmunoTherapy of Cancer
影响因子:10.6
doi:10.1136/jitc-2025-013818
Xu, Jin-Zhou; An, Ye; Sun, Jian-Xuan; Xiong, Yi-Fan; Liu, Chen-Qian; Zhang, Si-Han; Xia, Zhi-Yu; Hu, Jia; Zhang, Zi-Yi; Guo, Ci-Xiang; Liu, Bin-Lei; Guan, Wei; Wang, Shao-Gang; Xia, Qi-Dong
肿瘤
肿瘤免疫
信号转导
NF-κB
微生物学
PD-L1
囊泡
细胞生物学
前列腺癌
