日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Phosphorylation of Ku dictates DNA double-strand break (DSB) repair pathway choice in S phase.

Ku 的磷酸化决定了 S 期 DNA 双链断裂 (DSB) 修复途径的选择

Lee Kyung-Jong, Saha Janapriya, Sun Jingxin, Fattah Kazi R, Wang Shu-Chi, Jakob Burkhard, Chi Linfeng, Wang Shih-Ya, Taucher-Scholz Gisela, Davis Anthony J, Chen David J

Requirement of ATM-dependent monoubiquitylation of histone H2B for timely repair of DNA double-strand breaks

组蛋白H2B的ATM依赖性单泛素化对于及时修复DNA双链断裂是必需的

Moyal, Lilach; Lerenthal, Yaniv; Gana-Weisz, Mali; Mass, Gilad; So, Sairei; Wang, Shih-Ya; Eppink, Berina; Chung, Young Min; Shalev, Gil; Shema, Efrat; Shkedy, Dganit; Smorodinsky, Nechama I; van Vliet, Nicole; Kuster, Bernhard; Mann, Matthias; Ciechanover, Aaron; Dahm-Daphi, Jochen; Kanaar, Roland; Hu, Mickey C-T; Chen, David J; Oren, Moshe; Shiloh, Yosef

ATM-mediated phosphorylation of polynucleotide kinase/phosphatase is required for effective DNA double-strand break repair

ATM介导的多核苷酸激酶/磷酸酶磷酸化是有效修复DNA双链断裂所必需的。

Segal-Raz, Hava; Mass, Gilad; Baranes-Bachar, Keren; Lerenthal, Yaniv; Wang, Shih-Ya; Chung, Young Min; Ziv-Lehrman, Shelly; Ström, Cecilia E; Helleday, Thomas; Hu, Mickey C-T; Chen, David J; Shiloh, Yosef

Mycobacterium tuberculosis Ku can bind to nuclear DNA damage and sensitize mammalian cells to bleomycin sulfate

结核分枝杆菌Ku蛋白能够结合核DNA损伤位点,并使哺乳动物细胞对硫酸博来霉素敏感。

Castore, Reneau; Hughes, Cameron; Debeaux, Austin; Sun, Jingxin; Zeng, Cailing; Wang, Shih-Ya; Tatchell, Kelly; Shi, Runhua; Lee, Kyung-Jong; Chen, David J; Harrison, Lynn

The Ku80 carboxy terminus stimulates joining and artemis-mediated processing of DNA ends

Ku80羧基末端促进DNA末端的连接和artemis介导的加工

Weterings, Eric; Verkaik, Nicole S; Keijzers, Guido; Florea, Bogdan I; Wang, Shih-Ya; Ortega, Laura G; Uematsu, Naoya; Chen, David J; van Gent, Dik C

Ku recruits XLF to DNA double-strand breaks

Ku 招募 XLF 修复 DNA 双链断裂

Yano, Ken-ichi; Morotomi-Yano, Keiko; Wang, Shih-Ya; Uematsu, Naoya; Lee, Kyung-Jong; Asaithamby, Aroumougame; Weterings, Eric; Chen, David J