Oligodendrocyte-specific overexpression of human alpha-synuclein results in elevated MBP levels and inflammatory responses in TgM83 mice, mimicking the pathological features of multiple system atrophy.

人类α-突触核蛋白在少突胶质细胞中的特异性过表达导致TgM83小鼠体内MBP水平升高和炎症反应，模拟多系统萎缩的病理特征