Wang Wanhe相关文献与解析，生知库 | 链接生命科学的每一步

Tailoring obeticholic acid activity by iridium(III) complex conjugation to develop a farnesoidâ¯Xâ¯receptor probe.

通过铱(III)络合物偶联来调控奥贝胆酸活性，从而开发法尼醇X受体探针

doi:10.1016/j.jare.2024.10.028

Niu Dou, Wu Xiaolei, Zhang Yuxin, Wang Xueliang, Shiu-Hin Chan Daniel, Jing Shaozhen, Wong Chun-Yuen, Wang Wanhe, Leung Chung-Hang

信号转导

发表日期：2025

文献求助收藏

Probing mitochondrial peroxynitrite biogenesis by a N-morpholinoarylimine-based iridium(III) complex in drug-induced liver cells

利用基于N-吗啉代芳基亚胺的铱(III)配合物探测药物诱导肝细胞中线粒体过氧亚硝酸盐的生物合成

期刊:Redox Biology

影响因子:11.9

doi:10.1016/j.redox.2025.103805

Kong, Lingtan; Wang, Ling; Zhang, Zixi; Ye, Liuqi; Shiu-Hin Chan, Daniel; Wong, Chun-Yuen; Wang, Jing; Leung, Chung-Hang; Wang, Wanhe

KDM5 family as therapeutic targets in breast cancer: Pathogenesis and therapeutic opportunities and challenges

KDM5家族作为乳腺癌治疗靶点：发病机制、治疗机遇与挑战

期刊:Molecular Cancer

影响因子:33.9

doi:10.1186/s12943-024-02011-0

Li, Chang-Yun; Wang, Wanhe; Leung, Chung-Hang; Yang, Guan-Jun; Chen, Jiong

Development of a NIR Iridium(III) Complex-Based Probe for the Selective Detection of Iron(II) Ions

开发一种基于近红外铱(III)配合物的探针用于选择性检测二价铁离子

期刊:Biosensors-Basel

影响因子:5.6

doi:10.3390/bios14080369

Wang, Wanyi; Zhang, Zixi; Liu, Jingqi; Kong, Lingtan; Wang, Wanhe; Leung, Chung-Hang; Wang, Jing

发表日期：2024

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Recent Advances in Organometallic NIR Iridium(III) Complexes for Detection and Therapy

有机金属近红外铱(III)配合物在检测和治疗领域的最新进展

期刊:Molecules

影响因子:4.6

doi:10.3390/molecules29010256

Jing, Shaozhen; Wu, Xiaolei; Niu, Dou; Wang, Jing; Leung, Chung-Hang; Wang, Wanhe

发表日期：2024

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A robust luminescent assay for screening alkyladenine DNA glycosylase inhibitors to overcome DNA repair and temozolomide drug resistance.

一种用于筛选烷基腺嘌呤 DNA 糖基化酶抑制剂以克服 DNA 修复和替莫唑胺耐药性的稳健发光检测方法

期刊:Journal of Pharmaceutical Analysis

影响因子:8.9

doi:10.1016/j.jpha.2023.04.010

Song Ying-Qi, Li Guo-Dong, Niu Dou, Chen Feng, Jing Shaozhen, Wai Wong Vincent Kam, Wang Wanhe, Leung Chung-Hang

信号转导

发表日期：2023

文献求助收藏

Interference reduction isothermal nucleic acid amplification strategy for COVID-19 variant detection

用于新冠病毒变异株检测的干扰减少等温核酸扩增策略

期刊:Sensors and Actuators B-Chemical

影响因子:7.7

doi:10.1016/j.snb.2022.133006

Li, Guodong; Ko, Chung-Nga; Wang, Zikang; Chen, Feng; Wang, Wanhe; Ma, Dik-Lung; Leung, Chung-Hang

Development of an orally bioavailable selective inhibitor of the menin-MLL

开发一种口服生物利用度高的选择性menin-MLL抑制剂

期刊:Genes and Diseases

影响因子:

doi:10.1016/j.gendis.2022.10.005

Zhong, Hai-Jing; Wang, Wanhe; Zhou, Wei; Liang, Jia-Xin; Cheng, Yung-Chi; Ma, Dik-Lung; Leung, Chung-Hang

发表日期：2023

文献求助收藏

Development of a dual targeting scaffold of SET7/MLL inhibitor for castration-resistant prostate cancer treatment

开发用于治疗去势抵抗性前列腺癌的SET7/MLL双靶向抑制剂支架

期刊:Genes and Diseases

影响因子:

doi:10.1016/j.gendis.2023.01.034

Li, Guodong; Huang, Qi; Wai Wong, Vincent Kam; Wang, Wanhe; Leung, Chung-Hang

Direct Targeting of Gene Regulators by Iridium(III) and Rhodium(III) Complexes

铱(III)和铑(III)配合物对基因调控因子的直接靶向作用

Tailoring obeticholic acid activity by iridium(III) complex conjugation to develop a farnesoidâ¯Xâ¯receptor probe.

通过铱(III)络合物偶联来调控奥贝胆酸活性，从而开发法尼醇X受体探针

Probing mitochondrial peroxynitrite biogenesis by a N-morpholinoarylimine-based iridium(III) complex in drug-induced liver cells

利用基于N-吗啉代芳基亚胺的铱(III)配合物探测药物诱导肝细胞中线粒体过氧亚硝酸盐的生物合成

KDM5 family as therapeutic targets in breast cancer: Pathogenesis and therapeutic opportunities and challenges

KDM5家族作为乳腺癌治疗靶点：发病机制、治疗机遇与挑战

Development of a NIR Iridium(III) Complex-Based Probe for the Selective Detection of Iron(II) Ions

开发一种基于近红外铱(III)配合物的探针用于选择性检测二价铁离子

Recent Advances in Organometallic NIR Iridium(III) Complexes for Detection and Therapy

有机金属近红外铱(III)配合物在检测和治疗领域的最新进展

A robust luminescent assay for screening alkyladenine DNA glycosylase inhibitors to overcome DNA repair and temozolomide drug resistance.

一种用于筛选烷基腺嘌呤 DNA 糖基化酶抑制剂以克服 DNA 修复和替莫唑胺耐药性的稳健发光检测方法

Interference reduction isothermal nucleic acid amplification strategy for COVID-19 variant detection

用于新冠病毒变异株检测的干扰减少等温核酸扩增策略

Development of an orally bioavailable selective inhibitor of the menin-MLL

开发一种口服生物利用度高的选择性menin-MLL抑制剂

Development of a dual targeting scaffold of SET7/MLL inhibitor for castration-resistant prostate cancer treatment

开发用于治疗去势抵抗性前列腺癌的SET7/MLL双靶向抑制剂支架

Direct Targeting of Gene Regulators by Iridium(III) and Rhodium(III) Complexes

铱(III)和铑(III)配合物对基因调控因子的直接靶向作用

Tailoring obeticholic acid activity by iridium(III) complex conjugation to develop a farnesoidâ¯Xâ¯receptor probe.

通过铱(III)络合物偶联来调控奥贝胆酸活性，从而开发法尼醇X受体探针

Probing mitochondrial peroxynitrite biogenesis by a N-morpholinoarylimine-based iridium(III) complex in drug-induced liver cells

利用基于N-吗啉代芳基亚胺的铱(III)配合物探测药物诱导肝细胞中线粒体过氧亚硝酸盐的生物合成

KDM5 family as therapeutic targets in breast cancer: Pathogenesis and therapeutic opportunities and challenges

KDM5家族作为乳腺癌治疗靶点：发病机制、治疗机遇与挑战

Development of a NIR Iridium(III) Complex-Based Probe for the Selective Detection of Iron(II) Ions

开发一种基于近红外铱(III)配合物的探针用于选择性检测二价铁离子

Recent Advances in Organometallic NIR Iridium(III) Complexes for Detection and Therapy

有机金属近红外铱(III)配合物在检测和治疗领域的最新进展

A robust luminescent assay for screening alkyladenine DNA glycosylase inhibitors to overcome DNA repair and temozolomide drug resistance.

一种用于筛选烷基腺嘌呤 DNA 糖基化酶抑制剂以克服 DNA 修复和替莫唑胺耐药性的稳健发光检测方法

Interference reduction isothermal nucleic acid amplification strategy for COVID-19 variant detection

用于新冠病毒变异株检测的干扰减少等温核酸扩增策略

Development of an orally bioavailable selective inhibitor of the menin-MLL

开发一种口服生物利用度高的选择性menin-MLL抑制剂

Development of a dual targeting scaffold of SET7/MLL inhibitor for castration-resistant prostate cancer treatment

开发用于治疗去势抵抗性前列腺癌的SET7/MLL双靶向抑制剂支架

Tailoring obeticholic acid activity by iridium(III) complex conjugation to develop a farnesoidâ¯Xâ¯receptor probe.