文献库，生知库 | 链接生命科学的每一步

Targeted expression of the immunomodulatory peptide Scy by engineered Escherichia coli Nissle 1917 for alleviating enterotoxigenic E. coli infection

利用基因工程改造的大肠杆菌 Nissle 1917 靶向表达免疫调节肽 Scy，以减轻产肠毒素大肠杆菌感染。

doi:10.3389/fimmu.2026.1698243

Fu, Jie; Zhou, Lutong; Jiang, Xiao; Zhang, Hong; Chen, Yanli; Qiao, Lei; Song, Deguang; Lu, Zeqing; Wang, Tenghao; Jin, Mingliang; Zhang, Caiqiao; Wang, Yizhen; Cheng, Yuanzhi

Bacillus affects Taihe Silky Fowls growth performance, cecal microbiota, and metabolite during growing period

芽孢杆菌影响太和丝毛鸡生长期间的生长性能、盲肠微生物群和代谢产物

期刊:Poultry Science

影响因子:4.2

doi:10.1016/j.psj.2025.106251

Guo, Haoneng; Li, Wentao; Peng, Jianjun; Fan, Yuqing; Yang, Shuzhong; Mao, Huirong; Wang, Yizhen; Lu, Zeqing

Enhancement of gut barrier integrity by a Bacillus subtilis secreted metabolite through the GADD45A-Wnt/β-catenin pathway

枯草芽孢杆菌分泌的代谢物通过GADD45A-Wnt/β-catenin通路增强肠道屏障完整性

期刊:Imeta

影响因子:33.2

doi:10.1002/imt2.70005

Liu, Shiqi; Cai, Peiran; You, Wenjing; Yang, Mingshun; Tu, Yuang; Zhou, Yanbing; Valencak, Teresa G; Xiao, Yingping; Wang, Yizhen; Shan, Tizhong

Locoregional Immune Checkpoint Blockade and Remodeling of Lymph Nodes by Engineered Dendritic Cell-Derived Exosomes for Suppressing Tumor Progression and Metastasis

利用工程化树突状细胞来源的外泌体进行局部免疫检查点阻断和淋巴结重塑，以抑制肿瘤进展和转移

期刊:Advanced Science

影响因子:14.1

doi:10.1002/advs.202500139

Wang, Yizhen; Guo, Xiaomin; Qin, Jingya; Xue, Yifan; Zhang, Peng; Liu, Yadong; Chen, Moyang; Zhu, Guanghao; Song, Xinqiu; Cheng, Lili; Liu, Bo; Liu, Jie; Ren, Jie

Specifically targeted antimicrobial peptides synergize with bacterial-entrapping peptide against systemic MRSA infections

特异性靶向抗菌肽与细菌捕获肽协同作用，对抗全身性耐甲氧西林金黄色葡萄球菌（MRSA）感染。

期刊:Journal of Advanced Research

影响因子:13

doi:10.1016/j.jare.2024.01.023

Xu, Bocheng; Wang, Lin; Yang, Chen; Yan, Rong; Zhang, Pan; Jin, Mingliang; Du, Huahua; Wang, Yizhen

Integrated multi-omics reveals the Bacillus amyloliquefaciens BA40 against Clostridium perfringens infection in weaned piglets

整合多组学分析揭示了枯草芽孢杆菌BA40对断奶仔猪产气荚膜梭菌感染的抑制作用

期刊:Journal of Advanced Research

影响因子:13

doi:10.1016/j.jare.2025.01.033

Jiang, Zipeng; Su, Weifa; Yang, Mingzhi; Fu, Jie; Gong, Tao; Li, Wentao; Wen, Chaoyue; Wang, Xinxia; Wang, Fengqin; Jin, Mingliang; Wang, Yizhen; Lu, Zeqing

炎症/感染

发表日期：2025

文献求助收藏

3'-Sialyllactose and B. infantis synergistically alleviate gut inflammation and barrier dysfunction by enriching cross-feeding bacteria for short-chain fatty acid biosynthesis

3'-唾液酸乳糖和婴儿双歧杆菌协同作用，通过富集交叉喂养细菌促进短链脂肪酸生物合成，从而缓解肠道炎症和屏障功能障碍。

期刊:Gut Microbes

影响因子:11

doi:10.1080/19490976.2025.2486512

Yang, Mingzhi; Jiang, Zipeng; Zhou, Lutong; Chen, Nana; He, Huan; Li, Wentao; Yu, Zhixin; Jiao, Siming; Song, Deguang; Wang, Yizhen; Jin, Mingliang; Lu, Zeqing

Integrating digital health technologies to advance personalized cancer rehabilitation

整合数字健康技术，推进个性化癌症康复

期刊:International Journal of Surgery

影响因子:10.1

doi:10.1097/JS9.0000000000003207

Wang, Jie; Wang, Yizhen; Tian, Liqiong

The functions of gut microbiota-mediated bile acid metabolism in intestinal immunity

肠道菌群介导的胆汁酸代谢在肠道免疫中的作用

Integrating bile acid metabolism into precision nutrition strategies for improved swine performance

将胆汁酸代谢整合到精准营养策略中，以提高猪的生产性能

Targeted expression of the immunomodulatory peptide Scy by engineered Escherichia coli Nissle 1917 for alleviating enterotoxigenic E. coli infection

利用基因工程改造的大肠杆菌 Nissle 1917 靶向表达免疫调节肽 Scy，以减轻产肠毒素大肠杆菌感染。

Bacillus affects Taihe Silky Fowls growth performance, cecal microbiota, and metabolite during growing period

芽孢杆菌影响太和丝毛鸡生长期间的生长性能、盲肠微生物群和代谢产物

Enhancement of gut barrier integrity by a Bacillus subtilis secreted metabolite through the GADD45A-Wnt/β-catenin pathway

枯草芽孢杆菌分泌的代谢物通过GADD45A-Wnt/β-catenin通路增强肠道屏障完整性

Locoregional Immune Checkpoint Blockade and Remodeling of Lymph Nodes by Engineered Dendritic Cell-Derived Exosomes for Suppressing Tumor Progression and Metastasis

利用工程化树突状细胞来源的外泌体进行局部免疫检查点阻断和淋巴结重塑，以抑制肿瘤进展和转移

Specifically targeted antimicrobial peptides synergize with bacterial-entrapping peptide against systemic MRSA infections

特异性靶向抗菌肽与细菌捕获肽协同作用，对抗全身性耐甲氧西林金黄色葡萄球菌（MRSA）感染。

Integrated multi-omics reveals the Bacillus amyloliquefaciens BA40 against Clostridium perfringens infection in weaned piglets

整合多组学分析揭示了枯草芽孢杆菌BA40对断奶仔猪产气荚膜梭菌感染的抑制作用

3'-Sialyllactose and B. infantis synergistically alleviate gut inflammation and barrier dysfunction by enriching cross-feeding bacteria for short-chain fatty acid biosynthesis

3'-唾液酸乳糖和婴儿双歧杆菌协同作用，通过富集交叉喂养细菌促进短链脂肪酸生物合成，从而缓解肠道炎症和屏障功能障碍。

Integrating digital health technologies to advance personalized cancer rehabilitation

整合数字健康技术，推进个性化癌症康复