Glycodeoxycholic acid inhibits hepatocellular carcinoma by driving M1 polarization of macrophages via the S1PR2-NF-κB-NLRP3 pathway
糖脱氧胆酸通过S1PR2-NF-κB-NLRP3通路促进巨噬细胞M1极化，从而抑制肝细胞癌。
期刊:Jhep Reports
影响因子:7.5
doi:10.1016/j.jhepr.2026.101780
Deng, Mingxia; Liu, Jing; Zhang, Li; Zhang, Yichun; Hu, Haoyang; Dai, Jinyao; Dong, Shaohua; Jiang, Lushun; Ying, Shuaibing; Zhang, Zhijuan; Wang, Yujing; Zhu, Keer; Qiu, Yunqing; Lou, Yan
巨噬细胞
肿瘤
肿瘤免疫
巨噬细胞
信号转导
NF-κB
LRP3
NLRP3
细胞生物学
免疫/内分泌
