日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Intranasal parainfluenza virus type 5 (PIV5)-vectored RSV vaccine is safe and immunogenic in healthy adults in a phase 1 clinical study

一项 I 期临床研究表明,鼻内接种的 5 型副流感病毒 (PIV5) 载体 RSV 疫苗在健康成人中安全且具有免疫原性。

Spearman, Paul; Jin, Hong; Knopp, Kristeene; Xiao, Peng; Gingerich, Maria Cristina; Kidd, Jamie; Singh, Karnail; Tellier, Marinka; Radziewicz, Henry; Wu, Samuel; McGregor, Matthew; Freda, Barbara; Wang, Zhaoti; John, Susan P; Villinger, Francois J; He, Biao

Production of Cytomegalovirus Dense Bodies by Scalable Bioprocess Methods Maintains Immunogenicity and Improves Neutralizing Antibody Titers

利用可扩展的生物工艺方法生产巨细胞病毒致密体,可保持免疫原性并提高中和抗体滴度

Schneider-Ohrum, Kirsten; Cayatte, Corinne; Liu, Yi; Wang, Zhaoti; Irrinki, Alivelu; Cataniag, Floro; Nguyen, Nga; Lambert, Stacie; Liu, Hui; Aslam, Shahin; Duke, Greg; McCarthy, Michael P; McCormick, Louise

Cytomegalovirus vaccine strain towne-derived dense bodies induce broad cellular immune responses and neutralizing antibodies that prevent infection of fibroblasts and epithelial cells.

巨细胞病毒疫苗株 Towne 衍生的致密体可诱导广泛的细胞免疫反应和中和抗体,从而防止成纤维细胞和上皮细胞的感染

Cayatte Corinne, Schneider-Ohrum Kirsten, Wang Zhaoti, Irrinki Alivelu, Nguyen Nga, Lu Janine, Nelson Christine, Servat Esteban, Gemmell Lorraine, Citkowicz Andrzej, Liu Yi, Hayes Gregory, Woo Jennifer, Van Nest Gary, Jin Hong, Duke Gregory, McCormick A Louise