Wangsa Darawalee相关文献与解析，生知库 | 链接生命科学的每一步

Reactivation of Human X-Linked Gene and Stable X-Chromosome Inactivation Observed in Generation and Differentiation of iPSCs from a Female Patient with HNRNPH2 Mutation

在携带 HNRNPH2 突变的女性患者的 iPSC 生成和分化过程中观察到人类 X 连锁基因的重新激活和稳定的 X 染色体失活

doi:10.3390/cells14191486

Chen, Guibin; Rodriguez-Lopez, Alexander; Wangsa, Darawalee; Lomash, Richa Madan; Huang, Xiuli; Chen, Catherine Z; Bowling, Rodney A Jr; Ghousifam, Neda; Banks, Courtney J; Hurd, Kerstin A; Zou, Jizhong; Zheng, Wei

Human

发表日期：2025

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Dual inhibition of EGFR and PI3Kinase signaling in EGFR amplified triple negative breast cancer cells induces apoptosis and reduces tumor growth.

在 EGFR 扩增的三阴性乳腺癌细胞中，同时抑制 EGFR 和 PI3Kinase 信号传导可诱导细胞凋亡并减少肿瘤生长

期刊:

影响因子:

doi:10.1101/2025.06.03.657674

Wisniewski David J, Voeller Donna, Addissie Yonit A, Deshmukh Sachin Kumar, Wu Sharon, Lustberg Maryam B, Wangsa Darawalee, Wangsa Danny, Heselmeyer-Haddad Kerstin, Sledge George W Jr, Lipkowitz Stanley

Author Correction: ATR inhibition augments the efficacy of lurbinectedin in small-cell lung cancer

作者更正：ATR抑制剂可增强鲁比替定在小细胞肺癌中的疗效

期刊:EMBO Molecular Medicine

影响因子:8.3

doi:10.1038/s44321-024-00029-x

Schultz, Christopher W; Zhang, Yang; Elmeskini, Rajaa; Zimmermann, Astrid; Fu, Haiqing; Murai, Yasuhisa; Wangsa, Darawalee; Kumar, Suresh; Takahashi, Nobuyuki; Atkinson, Devon; Saha, Liton Kumar; Lee, Chien-Fei; Elenbaas, Brian; Desai, Parth; Sebastian, Robin; Sharma, Ajit Kumar; Abel, Melissa; Schroeder, Brett; Krishnamurthy, Manan; Bassel, Laurel L; Kumar, Rajesh; Roper, Nitin; Aladjem, Mirit; Zenke, Frank T; Ohler, Zoe Weaver; Pommier, Yves; Thomas, Anish

Hard wiring of normal tissue-specific chromosome-wide gene expression levels is an additional factor driving cancer type-specific aneuploidies

正常组织特异性染色体范围内基因表达水平的硬性调控是驱动癌症类型特异性非整倍体的另一个因素。

期刊:Genome Medicine

影响因子:11.2

doi:10.1186/s13073-021-00905-y

Patkar, Sushant; Heselmeyer-Haddad, Kerstin; Auslander, Noam; Hirsch, Daniela; Camps, Jordi; Bronder, Daniel; Brown, Markus; Chen, Wei-Dong; Lokanga, Rachel; Wangsa, Darawalee; Wangsa, Danny; Hu, Yue; Lischka, Annette; Braun, Rüdiger; Emons, Georg; Ghadimi, B Michael; Gaedcke, Jochen; Grade, Marian; Montagna, Cristina; Lazebnik, Yuri; Difilippantonio, Michael J; Habermann, Jens K; Auer, Gert; Ruppin, Eytan; Ried, Thomas

Deterministic assembly of chromosome ensembles in a programmable membrane trap array

在可编程膜陷阱阵列中确定性地组装染色体集合

期刊:Biofabrication

影响因子:8

doi:10.1088/1758-5090/ac1258

Babahosseini, Hesam; Wangsa, Darawalee; Pabba, Mani; Ried, Thomas; Misteli, Tom; DeVoe, Don L

发表日期：2021

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Bile acid-induced "Minority MOMP" promotes esophageal carcinogenesis while maintaining apoptotic resistance via Mcl-1

胆汁酸诱导的“少数 MOMP”通过 Mcl-1 促进食管癌变并保持凋亡抵抗

期刊:Oncogene

影响因子:6.9

doi:10.1038/s41388-019-1029-6

Yuan Xu, Deborah R Surman, Laurence Diggs, Sichuan Xi, Shaojian Gao, Devikala Gurusamy, Kaitlin McLoughlin, Justin Drake, Paul Feingold, Kate Brown, Danny Wangsa, Darawalee Wangsa, Xi Zhang, Thomas Ried, Jeremy L Davis, Jonathan Hernandez, Chuong D Hoang, Rhonda F Souza, David S Schrump, R Taylor Ri

Single Chromosome Aneuploidy Induces Genome-Wide Perturbation of Nuclear Organization and Gene Expression

单染色体非整倍体诱导全基因组范围内的核结构和基因表达紊乱

期刊:Neoplasia

影响因子:7.7

doi:10.1016/j.neo.2019.02.003

Braun, Rüdiger; Ronquist, Scott; Wangsa, Darawalee; Chen, Haiming; Anthuber, Lena; Gemoll, Timo; Wangsa, Danny; Koparde, Vishal; Hunn, Cynthia; Habermann, Jens K; Heselmeyer-Haddad, Kerstin; Rajapakse, Indika; Ried, Thomas

发表日期：2019

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Single-cell genetic analysis of clonal dynamics in colorectal adenomas indicates CDX2 gain as a predictor of recurrence

结直肠腺瘤克隆动态的单细胞遗传学分析表明，CDX2 扩增是复发的预测因子。

期刊:International Journal of Cancer

影响因子:4.7

doi:10.1002/ijc.31869

Fiedler, David; Heselmeyer-Haddad, Kerstin; Hirsch, Daniela; Hernandez, Leanora S; Torres, Irianna; Wangsa, Darawalee; Hu, Yue; Zapata, Luis; Rueschoff, Josef; Belle, Sebastian; Ried, Thomas; Gaiser, Timo

Dynamics of Genome Alterations in Crohn's Disease-Associated Colorectal Carcinogenesis

克罗恩病相关结直肠癌发生过程中基因组改变的动态变化

期刊:Clinical Cancer Research

影响因子:10.2

doi:10.1158/1078-0432.CCR-18-0630

Hirsch, Daniela; Wangsa, Darawalee; Zhu, Yuelin J; Hu, Yue; Edelman, Daniel C; Meltzer, Paul S; Heselmeyer-Haddad, Kerstin; Ott, Claudia; Kienle, Peter; Galata, Christian; Horisberger, Karoline; Ried, Thomas; Gaiser, Timo

Haplotype-resolved reconstruction and functional interrogation of cancer karyotypes

基于单倍型解析的癌症核型重建和功能分析

Reactivation of Human X-Linked Gene and Stable X-Chromosome Inactivation Observed in Generation and Differentiation of iPSCs from a Female Patient with HNRNPH2 Mutation

在携带 HNRNPH2 突变的女性患者的 iPSC 生成和分化过程中观察到人类 X 连锁基因的重新激活和稳定的 X 染色体失活

Dual inhibition of EGFR and PI3Kinase signaling in EGFR amplified triple negative breast cancer cells induces apoptosis and reduces tumor growth.

在 EGFR 扩增的三阴性乳腺癌细胞中，同时抑制 EGFR 和 PI3Kinase 信号传导可诱导细胞凋亡并减少肿瘤生长

Author Correction: ATR inhibition augments the efficacy of lurbinectedin in small-cell lung cancer

作者更正：ATR抑制剂可增强鲁比替定在小细胞肺癌中的疗效

Hard wiring of normal tissue-specific chromosome-wide gene expression levels is an additional factor driving cancer type-specific aneuploidies

正常组织特异性染色体范围内基因表达水平的硬性调控是驱动癌症类型特异性非整倍体的另一个因素。

Deterministic assembly of chromosome ensembles in a programmable membrane trap array

在可编程膜陷阱阵列中确定性地组装染色体集合

Bile acid-induced "Minority MOMP" promotes esophageal carcinogenesis while maintaining apoptotic resistance via Mcl-1

胆汁酸诱导的“少数 MOMP”通过 Mcl-1 促进食管癌变并保持凋亡抵抗

Single Chromosome Aneuploidy Induces Genome-Wide Perturbation of Nuclear Organization and Gene Expression

单染色体非整倍体诱导全基因组范围内的核结构和基因表达紊乱

Single-cell genetic analysis of clonal dynamics in colorectal adenomas indicates CDX2 gain as a predictor of recurrence

结直肠腺瘤克隆动态的单细胞遗传学分析表明，CDX2 扩增是复发的预测因子。

Dynamics of Genome Alterations in Crohn's Disease-Associated Colorectal Carcinogenesis

克罗恩病相关结直肠癌发生过程中基因组改变的动态变化