The Raf kinase inhibitor PLX5568 slows cyst proliferation in rat polycystic kidney disease but promotes renal and hepatic fibrosis
Raf激酶抑制剂PLX5568可减缓大鼠多囊肾病中囊肿的增殖,但会促进肾脏和肝脏纤维化。
期刊:Nephrology Dialysis Transplantation
影响因子:5.6
doi:10.1093/ndt/gfr432
Buchholz, Bjoern; Klanke, Bernd; Schley, Gunnar; Bollag, Gideon; Tsai, James; Kroening, Sven; Yoshihara, Daisuke; Wallace, Darren P; Kraenzlin, Bettina; Gretz, Norbert; Hirth, Peter; Eckardt, Kai-Uwe; Bernhardt, Wanja M