日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Tuning potency for precision: the role of the G4-ligand in G4-ligand conjugated oligonucleotides targeting individual G-quadruplex DNA structures

调节效力以实现精准靶向：G4配体在靶向特定G-四链体DNA结构的G4配体偶联寡核苷酸中的作用

期刊:RSC Chemical Biology
影响因子:3.1
doi:10.1039/d5cb00302d
Abrahamsson, Alva; Khwaja, Sakina; Berner, Andreas; Nath Das, Rabindra; Aasumets, Koit; Chaudhari, Namrata; Wanrooij, Sjoerd; Chorell, Erik
发表日期：2026
文献求助 收藏

The POLγ Y951N patient mutation disrupts the switch between DNA synthesis and proofreading, triggering mitochondrial DNA instability

POLγ Y951N 患者突变会破坏 DNA 合成和校正之间的转换，从而引发线粒体 DNA 不稳定。

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2417477122
Forslund, Josefin M E; Nguyen, Tran V H; Parkash, Vimal; Berner, Andreas; Goffart, Steffi; Pohjoismäki, Jaakko L O; Wanrooij, Paulina H; Johansson, Erik; Wanrooij, Sjoerd
线粒体
发表日期：2025
文献求助 收藏

TEFM facilitates transition from RNA synthesis to DNA synthesis at H-strand replication origin of mtDNA.

TEFM 促进线粒体 DNA H 链复制起点处从 RNA 合成向 DNA 合成的过渡

期刊:Communications Biology
影响因子:5.1
doi:10.1038/s42003-025-07645-4
Matsuda Shigeru, Nakayama Masunari, Do Yura, Ishiuchi Takashi, Yagi Mikako, Wanrooij Sjoerd, Nakada Kazuto, Wei Fan-Yan, Ichiyanagi Kenji, Sasaki Hiroyuki, Kang Dongchon, Yasukawa Takehiro
其它
线粒体
发表日期：2025
文献求助 收藏

Activating AMPK improves pathological phenotypes due to mtDNA depletion.

激活 AMPK 可改善由 mtDNA 耗竭引起的病理表型

期刊:FEBS Journal
影响因子:4.2
doi:10.1111/febs.70006
Carvalho Gustavo, Nguyen Tran V H, Repolês Bruno, Forslund Josefin M E, Wijethunga W M Ruchitha Rukmal, Ranjbarian Farahnaz, Mendes Isabela C, Gorospe Choco Michael, Chaudhari Namrata, Falabella Micol, Doimo Mara, Wanrooij Sjoerd, Pitceathly Robert D S, Hofer Anders, Wanrooij Paulina H
信号转导
AMPK
发表日期：2025
文献求助 收藏

Linker Design Principles for the Precision Targeting of Oncogenic G-Quadruplex DNA with G4-Ligand-Conjugated Oligonucleotides

利用G4配体偶联寡核苷酸精准靶向致癌G-四链体DNA的连接子设计原则

期刊:Bioconjugate Chemistry
影响因子:3.9
doi:10.1021/acs.bioconjchem.5c00008
Abrahamsson, Alva; Berner, Andreas; Golebiewska-Pikula, Justyna; Chaudhari, Namrata; Keskitalo, Emelie; Lindgren, Cecilia; Chmielewski, Marcin K; Wanrooij, Sjoerd; Chorell, Erik
肿瘤
肿瘤免疫
发表日期：2025
文献求助 收藏

MRE11-independent effects of Mirin on mitochondrial DNA integrity and cellular immune responses.

Mirin 对线粒体 DNA 完整性和细胞免疫反应的 MRE11 非依赖性影响

期刊:Molecular Biology of the Cell
影响因子:2.7
doi:10.1091/mbc.E24-01-0002
Aasumets Koit, Hangas Anu, Fragkoulis Georgios, Bader Cyrielle P J, Erdinc Direnis, Wanrooij Sjoerd, Wanrooij Paulina H, Goffart Steffi, Pohjoismäki Jaakko L O
细胞生物学
线粒体
发表日期：2025
文献求助 收藏

G4-Ligand-Conjugated Oligonucleotides Mediate Selective Binding and Stabilization of Individual G4 DNA Structures

G4配体偶联寡核苷酸介导对特定G4 DNA结构的选择性结合和稳定作用

期刊:Journal of the American Chemical Society
影响因子:15.6
doi:10.1021/jacs.3c14408
Berner, Andreas; Das, Rabindra Nath; Bhuma, Naresh; Golebiewska, Justyna; Abrahamsson, Alva; Andréasson, Måns; Chaudhari, Namrata; Doimo, Mara; Bose, Partha Pratim; Chand, Karam; Strömberg, Roger; Wanrooij, Sjoerd; Chorell, Erik
发表日期：2024
文献求助 收藏

Preferential binding of ADP-bound mitochondrial HSP70 to the nucleotide exchange factor GRPEL1 over GRPEL2

ADP结合的线粒体HSP70优先与核苷酸交换因子GRPEL1而非GRPEL2结合。

期刊:Protein Science
影响因子:5.2
doi:10.1002/pro.5190
Manjunath, Pooja; Stojkovič, Gorazd; Euro, Liliya; Konovalova, Svetlana; Wanrooij, Sjoerd; Koski, Kristian; Tyynismaa, Henna
SP7
线粒体
HSP70
发表日期：2024
文献求助 收藏

Enhanced mitochondrial G-quadruplex formation impedes replication fork progression leading to mtDNA loss in human cells

线粒体G-四链体形成增强会阻碍复制叉的延伸，导致人类细胞中线粒体DNA的丢失。

期刊:Nucleic Acids Research
影响因子:13.1
doi:10.1093/nar/gkad535
Doimo, Mara; Chaudhari, Namrata; Abrahamsson, Sanna; L'Hôte, Valentin; Nguyen, Tran V H; Berner, Andreas; Ndi, Mama; Abrahamsson, Alva; Das, Rabindra Nath; Aasumets, Koit; Goffart, Steffi; Pohjoismäki, Jaakko L O; López, Marcela Dávila; Chorell, Erik; Wanrooij, Sjoerd
线粒体
细胞生物学
发表日期：2023
文献求助 收藏

A complementary chemical probe approach towards customized studies of G-quadruplex DNA structures in live cells

一种用于活细胞中G-四链体DNA结构定制研究的互补化学探针方法

期刊:Chemical Science
影响因子:7.4
doi:10.1039/d1sc05816a
Prasad, Bagineni; Doimo, Mara; Andréasson, Måns; L'Hôte, Valentin; Chorell, Erik; Wanrooij, Sjoerd
细胞生物学
发表日期：2022
文献求助 收藏