日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

mTOR-driven autophagy suppression defines metabolic vulnerability in CDK4/6 inhibitor-resistant HR(+)/HER2(-) breast cancer.

mTOR 驱动的自噬抑制定义了 CDK4/6 抑制剂耐药的 HR(+)/HER2(-) 乳腺癌的代谢脆弱性。

von Wichert Luise, Stroh Alina, Witt Marie, Wanzel Michael, Mernberger Marco, Griewing Sebastian, Wündisch Thomas, Pfitzner Berit M, Teply-Szymanski Julia, Litmeyer Anne-Sophie, Denkert Carsten, Wagner Uwe, Stiewe Thorsten, Gremke Niklas

Leptin-dependent fat accumulation triggers autophagy in metabolic dysfunction-associated steatohepatitis model.

瘦素依赖性脂肪积累可触发代谢功能障碍相关脂肪性肝炎模型中的自噬。

Polte Sophia C H, Matono Tomomitsu, Okamoto Kinya, Koda Masahiko, Ebrahimifard Ali, Wanzel Michael, Stiewe Thorsten, Wissniowski Thaddeus T, Matrood Sami, Di Fazio Pietro

Targeting PI3K inhibitor resistance in breast cancer with metabolic drugs.

利用代谢药物靶向治疗乳腺癌中的PI3K抑制剂耐药性

Gremke Niklas, Besong Isabelle, Stroh Alina, von Wichert Luise, Witt Marie, Elmshäuser Sabrina, Wanzel Michael, Fromm Martin F, Taudte R Verena, Schmatloch Sabine, Karn Thomas, Reinisch Mattea, Hirmas Nader, Loibl Sibylle, Wündisch Thomas, Litmeyer Anne-Sophie, Jank Paul, Denkert Carsten, Griewing Sebastian, Wagner Uwe, Stiewe Thorsten

Deep CRISPR mutagenesis characterizes the functional diversity of TP53 mutations.

深度 CRISPR 诱变表征了 TP53 突变的功能多样性

Funk Julianne S, Klimovich Maria, Drangenstein Daniel, Pielhoop Ole, Hunold Pascal, Borowek Anna, Noeparast Maxim, Pavlakis Evangelos, Neumann Michelle, Balourdas Dimitrios-Ilias, Kochhan Katharina, Merle Nastasja, Bullwinkel Imke, Wanzel Michael, Elmshäuser Sabrina, Teply-Szymanski Julia, Nist Andrea, Procida Tara, Bartkuhn Marek, Humpert Katharina, Mernberger Marco, Savai Rajkumar, Soussi Thierry, Joerger Andreas C, Stiewe Thorsten

Treatment of scaphoid fractures and pseudarthroses with the human allogeneic cortical bone screw. A multicentric retrospective study

采用人源同种异体皮质骨螺钉治疗舟骨骨折和假关节:一项多中心回顾性研究

Sailer, Simon; Lechner, Simon; Floßmann, Andreas; Wanzel, Michael; Habeler, Kerstin; Krasny, Christian; Borchert, Gudrun H