日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The invasion pore induced by Toxoplasma gondii

弓形虫引起的入侵孔

Kegawa, Yuto; Male, Frances; Jiménez-Munguía, Irene; Blank, Paul S; Mekhedov, Elena; Ward, Gary E; Zimmerberg, Joshua

Motility-dependent processes in Toxoplasma gondii tachyzoites and bradyzoites: same same but different

弓形虫速殖子和缓殖子的运动依赖性过程:相同却又不同

Kent, Robyn S; Ward, Gary E

MyosinA is a druggable target in the widespread protozoan parasite Toxoplasma gondii

肌球蛋白A是广泛分布的原生动物寄生虫弓形虫的一个可药物靶点。

Kelsen, Anne; Kent, Robyn S; Snyder, Anne K; Wehri, Eddie; Bishop, Stephen J; Stadler, Rachel V; Powell, Cameron; Martorelli di Genova, Bruno; Rompikuntal, Pramod K; Boulanger, Martin J; Warshaw, David M; Westwood, Nicholas J; Schaletzky, Julia; Ward, Gary E

Parasites lacking the micronemal protein MIC2 are deficient in surface attachment and host cell egress, but remain virulent in vivo

缺乏微粒体蛋白MIC2的寄生虫在表面黏附和宿主细胞逸出方面存在缺陷,但在体内仍具有致病性。

Gras, Simon; Jackson, Allison; Woods, Stuart; Pall, Gurman; Whitelaw, Jamie; Leung, Jacqueline M; Ward, Gary E; Roberts, Craig W; Meissner, Markus

Global Analysis of Palmitoylated Proteins in Toxoplasma gondii

弓形虫中棕榈酰化蛋白的全球分析

Foe, Ian T; Child, Matthew A; Majmudar, Jaimeen D; Krishnamurthy, Shruthi; van der Linden, Wouter A; Ward, Gary E; Martin, Brent R; Bogyo, Matthew

Yeast three-hybrid screen identifies TgBRADIN/GRA24 as a negative regulator of Toxoplasma gondii bradyzoite differentiation.

酵母三杂交筛选鉴定出 TgBRADIN/GRA24 是弓形虫缓殖子分化的负调控因子

Odell Anahi V, Tran Fanny, Foderaro Jenna E, Poupart Séverine, Pathak Ravi, Westwood Nicholas J, Ward Gary E

Identification of Cryptosporidium parvum active chemical series by Repurposing the open access malaria box

利用开放获取的疟疾信息库鉴定小隐孢子虫活性化学系列

Bessoff, Kovi; Spangenberg, Thomas; Foderaro, Jenna E; Jumani, Rajiv S; Ward, Gary E; Huston, Christopher D

A Toxoplasma gondii class XIV myosin, expressed in Sf9 cells with a parasite co-chaperone, requires two light chains for fast motility.

弓形虫 XIV 类肌球蛋白在 Sf9 细胞中与寄生虫辅助伴侣蛋白一起表达,需要两条轻链才能快速运动

Bookwalter Carol S, Kelsen Anne, Leung Jacqueline M, Ward Gary E, Trybus Kathleen M

Disruption of TgPHIL1 alters specific parameters of Toxoplasma gondii motility measured in a quantitative, three-dimensional live motility assay

TgPHIL1基因的破坏会改变弓形虫运动性的特定参数,这些参数是通过定量三维活体运动性检测方法测得的。

Leung, Jacqueline M; Rould, Mark A; Konradt, Christoph; Hunter, Christopher A; Ward, Gary E

Identification of TgCBAP, a novel cytoskeletal protein that localizes to three distinct subcompartments of the Toxoplasma gondii pellicle

鉴定出TgCBAP,一种定位于弓形虫表膜三个不同亚区室的新型细胞骨架蛋白。

Tilley, Lucas D; Krishnamurthy, Shruthi; Westwood, Nicholas J; Ward, Gary E