日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Reduction in myofilament Ca(2+) sensitivity partially ameliorates the cardiac phenotype in hypertrophic cardiomyopathy linked to a TnT-R92Q mutation.

肌丝 Ca(2+) 敏感性降低可部分改善与 TnT-R92Q 突变相关的肥厚型心肌病的心脏表型

Langa Paulina, Bacon Angelie, Warren Chad M, Chowdhury Shamim A K, Halas Monika, Fernandes Aurelia A, McCauley Mark D, Goldspink Paul H, Solaro R John, Wolska Beata M

Signaling pathway alterations in hearts of a porcine model harboring a β-myosin heavy chain (MYH7-R403Q) gene variant

携带β-肌球蛋白重链(MYH7-R403Q)基因变异的猪模型心脏中的信号通路改变

Warren, Chad M; Ryba, David M; Geist, Gail E; Coronado, Aileen Castro; Wolska, Beata M; Goldspink, Paul H; Solaro, R John

Cardiomyocyte external mechanical unloading activates modifications of α-actinin differently from sarcomere-originated unloading.

心肌细胞外部机械卸载激活α-肌动蛋白修饰的方式与肌节来源的卸载不同

Solís Christopher, Warren Chad M, Dittloff Kyle, DiNello Elisabeth, Solaro R John, Russell Brenda

Effects of Sarcomere Activators and Inhibitors Targeting Myosin Cross-Bridges on Ca(2+)-Activation of Mature and Immature Mouse Cardiac Myofilaments

肌节激活剂和抑制剂靶向肌球蛋白横桥对成熟和未成熟小鼠心肌肌丝Ca(2+)激活的影响

Halas, Monika; Langa, Paulina; Warren, Chad M; Goldspink, Paul H; Wolska, Beata M; Solaro, R John

Peroxisome proliferator-activated receptor-α expression induces alterations in cardiac myofilaments in a pressure-overload model of hypertrophy

过氧化物酶体增殖激活受体α表达诱导压力超负荷肥大模型中心肌肌丝的改变

Karam, Chehade N; Warren, Chad M; Henze, Marcus; Banke, Natasha H; Lewandowski, E Douglas; Solaro, R John

Impact of anesthesia and storage on posttranslational modifications of cardiac myofilament proteins

麻醉和储存对心肌肌丝蛋白翻译后修饰的影响

Utter, Megan S; Warren, Chad M; Solaro, R John

Ceramide-mediated depression in cardiomyocyte contractility through PKC activation and modulation of myofilament protein phosphorylation

神经酰胺通过激活蛋白激酶C (PKC) 和调节肌丝蛋白磷酸化来抑制心肌细胞收缩力。

Simon, Jillian N; Chowdhury, Shamim A K; Warren, Chad M; Sadayappan, Sakthivel; Wieczorek, David F; Solaro, R John; Wolska, Beata M

Desensitization of myofilaments to Ca2+ as a therapeutic target for hypertrophic cardiomyopathy with mutations in thin filament proteins

肌丝对Ca2+的脱敏可作为治疗由细丝蛋白突变引起的肥厚型心肌病的一种靶点

Alves, Marco L; Dias, Fernando A L; Gaffin, Robert D; Simon, Jillian N; Montminy, Eric M; Biesiadecki, Brandon J; Hinken, Aaron C; Warren, Chad M; Utter, Megan S; Davis, Robert T Rd; Sakthivel, Sadayappan; Robbins, Jeffrey; Wieczorek, David F; Solaro, R John; Wolska, Beata M

Maintenance of adult cardiac function requires the chromatin factor Asxl2

维持成年心脏功能需要染色质因子Asxl2。

Lai, Hsiao-Lei; Grachoff, Milana; McGinley, Andrea L; Khan, Farida F; Warren, Chad M; Chowdhury, Shamim A K; Wolska, Beata M; Solaro, R John; Geenen, David L; Wang, Q Tian

Expression of slow skeletal TnI in adult mouse hearts confers metabolic protection to ischemia

成年小鼠心脏中慢肌钙蛋白I的表达赋予缺血代谢保护作用

Pound, Kayla M; Arteaga, Grace M; Fasano, Mathew; Wilder, Tanganyika; Fischer, Susan K; Warren, Chad M; Wende, Adam R; Farjah, Mariam; Abel, E Dale; Solaro, R John; Lewandowski, E Douglas