A randomized, double-blind, phase 2b study to investigate the efficacy, safety, tolerability and pharmacokinetics of a single-dose regimen of ferroquine with artefenomel in adults and children with uncomplicated Plasmodium falciparum malaria
一项随机、双盲、2b期研究，旨在探讨单剂量氟喹诺酮联合阿特芬诺美治疗成人和儿童单纯性恶性疟疾的疗效、安全性、耐受性和药代动力学。
期刊:Malaria Journal
影响因子:3
doi:10.1186/s12936-021-03749-4
Adoke, Yeka; Zoleko-Manego, Rella; Ouoba, Serge; Tiono, Alfred B; Kaguthi, Grace; Bonzela, Juvêncio Eduardo; Duong, Tran Thanh; Nahum, Alain; Bouyou-Akotet, Marielle; Ogutu, Bernhards; Ouedraogo, Alphonse; Macintyre, Fiona; Jessel, Andreas; Laurijssens, Bart; Cherkaoui-Rbati, Mohammed H; Cantalloube, Cathy; Marrast, Anne Claire; Bejuit, Raphaël; White, David; Wells, Timothy N C; Wartha, Florian; Leroy, Didier; Kibuuka, Afizi; Mombo-Ngoma, Ghyslain; Ouattara, Daouda; Mugenya, Irène; Phuc, Bui Quang; Bohissou, Francis; Mawili-Mboumba, Denise P; Olewe, Fredrick; Soulama, Issiaka; Tinto, Halidou
