Waxman David J相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

HDI-STARR-seq Identifies Functional GH-regulated Sex-Biased Hepatocyte Enhancers Linked to Liver Metabolism and Disease

HDI-STARR-seq 鉴定出与肝脏代谢和疾病相关的、受生长激素调控的、性别偏向性肝细胞增强子的功能。

doi:10.1101/2025.11.02.686175

Chang, Ting-Ya; Waxman, David J

免疫/内分泌

细胞生物学

发表日期：2026

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Single Nucleus MultiOmics Links Novel Transcription Factor Motifs to Murine Hepatic Sex Differences in Chromatin Accessibility and Metabolic Dysfunction-Associated Steatotic Liver Disease

单核多组学将新型转录因子基序与小鼠肝脏染色质可及性的性别差异以及代谢功能障碍相关的脂肪肝疾病联系起来

doi:10.1101/2025.10.31.685903

Karri, Kritika; Chang, Ting-Ya; Pyatkov, Maxim; Gandhi, Shashi; Siggers, Trevor; Waxman, David J

发表日期：2025

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Disease-associated mutations in the STAT5B SH2 domain reprogram hepatic cholesterol and lipid metabolism.

STAT5B SH2 结构域中的疾病相关突变会重编程肝脏胆固醇和脂质代谢。

doi:10.1101/2025.11.27.691004

Lee Hye Kyung, Pyatkov Maxim, Gavrilova Oksana, Liu Naili, Demby Tamar, Ye Bingtian, Furth Priscilla A, Hennighausen Lothar, Waxman David J

发表日期：2025

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Steatotic liver disease induced by TCPOBOP-activated hepatic constitutive androstane receptor: primary and secondary gene responses with links to disease progression.

TCPOBOP激活的肝脏组成型雄甾烷受体诱发的脂肪肝疾病：与疾病进展相关的原发性和继发性基因反应

期刊:Toxicological Sciences

影响因子:4.1

doi:10.1093/toxsci/kfae057

Sonkar Ravi, Ma Hong, Waxman David J

发表日期：2024

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HDI-STARR-seq: Condition-specific enhancer discovery in mouse liver in vivo

HDI-STARR-seq：小鼠肝脏体内特定条件增强子发现

期刊:BMC Genomics

影响因子:3.7

doi:10.1186/s12864-024-11162-9

Chang, Ting-Ya; Waxman, David J

发表日期：2024

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Direct and systemic actions of growth hormone receptor (GHR)-signaling on hepatic glycolysis, de novo lipogenesis and insulin sensitivity, associated with steatosis

生长激素受体 (GHR) 信号对肝糖酵解、从头脂肪生成和胰岛素敏感性的直接和系统性作用与脂肪变性相关

期刊:Metabolism-Clinical and Experimental

影响因子:11.9

doi:10.1016/j.metabol.2023.155589

Vázquez-Borrego, Mari C; Del Río-Moreno, Mercedes; Pyatkov, Maxim; Sarmento-Cabral, André; Mahmood, Mariyah; Pelke, Natalie; Wnek, Magdalena; Cordoba-Chacon, Jose; Waxman, David J; Puchowicz, Michelle A; McGuinness, Owen P; Kineman, Rhonda D

免疫/内分泌

发表日期：2023

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Growth Hormone Accelerates Recovery From Acetaminophen-Induced Murine Liver Injury

生长激素加速对乙酰氨基酚诱导的小鼠肝损伤的恢复

doi:10.1101/2023.04.17.537197

Everton, Elissa; Del Rio-Moreno, Mercedes; Villacorta-Martin, Carlos; Singh Bawa, Pushpinder; Lindstrom-Vautrin, Jonathan; Muramatsu, Hiromi; Rizvi, Fatima; Smith, Anna R; Tam, Ying; Pardi, Norbert; Kineman, Rhonda; Waxman, David J; Gouon-Evans, Valerie

免疫/内分泌

发表日期：2023

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Impact of Neonatal Activation of Nuclear Receptor CAR (Nr1i3) on Cyp2 Gene Expression in Adult Mouse Liver

新生儿期核受体CAR（Nr1i3）激活对成年小鼠肝脏Cyp2基因表达的影响

期刊:Toxicological Sciences

影响因子:4.1

doi:10.1093/toxsci/kfac032

Shin, Aram; Waxman, David J

发表日期：2022

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Optical scattering as an early marker of apoptosis during chemotherapy and antiangiogenic therapy in murine models of prostate and breast cancer

在小鼠前列腺癌和乳腺癌模型中，光散射可作为化疗和抗血管生成治疗期间细胞凋亡的早期标志物

期刊:Neoplasia

影响因子:7.7

doi:10.1016/j.neo.2021.01.005

Tabassum, Syeda; Tank, Anup; Wang, Fay; Karrobi, Kavon; Vergato, Cameron; Bigio, Irving J; Waxman, David J; Roblyer, Darren

细胞生物学

发表日期：2021

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MAnorm2 for quantitatively comparing groups of ChIP-seq samples

MAnorm2 用于定量比较 ChIP-seq 样本组

期刊:Genome Research

影响因子:5.5

doi:10.1101/gr.262675.120

Tu, Shiqi; Li, Mushan; Chen, Haojie; Tan, Fengxiang; Xu, Jian; Waxman, David J; Zhang, Yijing; Shao, Zhen

发表日期：2021

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