日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Next generation APOBEC3 inhibitors: optimally designed for potency and nuclease stability

新一代APOBEC3抑制剂:针对效力和核酸酶稳定性进行了优化设计

Hedger, Adam K; Myint, Wazo; Lee, Jeong Min; Suchenski Loustaunau, Diego; Balachandran, Vanivilasini; Shaqra, Ala M; Kurt Yilmaz, Nese; Watts, Jonathan K; Matsuo, Hiroshi; Schiffer, Celia A

NMR in the Age of Modern Biomedical Research and Drug Discovery

核磁共振技术在现代生物医学研究和药物发现中的应用

Lu, Xiuxiu; Myint, Wazo; Muli, Christine S; Larion, Mioara; Matsuo, Hiroshi; Walters, Kylie J

A structure-based designed small molecule depletes hRpn13Pru and a select group of KEN box proteins

一种基于结构设计的小分子能够消耗 hRpn13Pru 和特定 KEN 盒蛋白。

Xiuxiu Lu,Monika Chandravanshi,Venkata R Sabbasani,Snehal Gaikwad,V Keith Hughitt,Nana Gyabaah-Kessie,Bradley T Scroggins,Sudipto Das,Wazo Myint,Michelle E Clapp,Charles D Schwieters,Marzena A Dyba,Derek L Bolhuis,Janusz W Koscielniak,Thorkell Andresson,Michael J Emanuele,Nicholas G Brown,Hiroshi Matsuo,Raj Chari,Deborah E Citrin,Beverly A Mock,Rolf E Swenson,Kylie J Walters

Next generation APOBEC3 inhibitors: Optimally designed for potency and nuclease stability

新一代APOBEC3抑制剂:针对效力和核酸酶稳定性进行了优化设计

Hedger, Adam K; Myint, Wazo; Lee, Jeong Min; Suchenski-Loustaunau, Diego; Balachandran, Vanivilasini; Shaqra, Ala M; Kurt-Yilmaz, Nese; Watts, Jonathan K; Matsuo, Hiroshi; Schiffer, Celia A

E6AP AZUL interaction with UBQLN1/2 in cells, condensates, and an AlphaFold-NMR integrated structure

E6AP AZUL 与细胞、凝聚物中的 UBQLN1/2 相互作用以及 AlphaFold-NMR 集成结构

Gwen R Buel, Xiang Chen, Wazo Myint, Olumide Kayode, Varvara Folimonova, Anthony Cruz, Katarzyna A Skorupka, Hiroshi Matsuo, Kylie J Walters

Structure of the catalytically active APOBEC3G bound to a DNA oligonucleotide inhibitor reveals tetrahedral geometry of the transition state

催化活性APOBEC3G与DNA寡核苷酸抑制剂结合的结构揭示了过渡态的四面体几何构型

Maiti, Atanu; Hedger, Adam K; Myint, Wazo; Balachandran, Vanivilasini; Watts, Jonathan K; Schiffer, Celia A; Matsuo, Hiroshi

Crystal Structure of a Soluble APOBEC3G Variant Suggests ssDNA to Bind in a Channel that Extends between the Two Domains

可溶性 APOBEC3G 变体的晶体结构表明 ssDNA 结合在两个域之间延伸的通道中

Atanu Maiti, Wazo Myint, Krista A Delviks-Frankenberry, Shurong Hou, Tapan Kanai, Vanivilasini Balachandran, Christina Sierra Rodriguez, Rashmi Tripathi, Nese Kurt Yilmaz, Vinay K Pathak, Celia A Schiffer, Hiroshi Matsuo

Crystal structure of the catalytic domain of HIV-1 restriction factor APOBEC3G in complex with ssDNA.

HIV-1 限制因子 APOBEC3G 催化结构域与 ssDNA 复合物的晶体结构

Maiti Atanu, Myint Wazo, Kanai Tapan, Delviks-Frankenberry Krista, Sierra Rodriguez Christina, Pathak Vinay K, Schiffer Celia A, Matsuo Hiroshi

Drug Resistance Mutations Alter Dynamics of Inhibitor-Bound HIV-1 Protease

耐药突变改变了抑制剂结合的HIV-1蛋白酶的动态变化

Cai, Yufeng; Myint, Wazo; Paulsen, Janet L; Schiffer, Celia A; Ishima, Rieko; Kurt Yilmaz, Nese

Differential Flap Dynamics in Wild-type and a Drug Resistant Variant of HIV-1 Protease Revealed by Molecular Dynamics and NMR Relaxation

分子动力学和核磁共振弛豫揭示野生型和耐药型HIV-1蛋白酶变体中不同的瓣状结构动力学

Cai, Yufeng; Yilmaz, Nese Kurt; Myint, Wazo; Ishima, Rieko; Schiffer, Celia A