Weaver C David相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

The pathway-independent positive allosteric modulator C1 allows for the identification of active Y(4) receptor relevant positions

通路非依赖性正向变构调节剂C1可用于识别活性Y(4)受体的相关位点。

期刊:Cellular and Molecular Life Sciences

影响因子:6.2

doi:10.1007/s00018-025-06019-7

Schüß, Corinna; Vu, Oanh; Pelczyk, Tim; Schubert, Mario; Du, Yu; Stichel, Jan; Weaver, C David; Meiler, Jens; Beck-Sickinger, Annette G

发表日期：2026

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Similar Binding Mode of a 5-Sulfonylthiouracil Derivative Antagonist at Chemerin Receptors CMKLR1 and GPR1

5-磺酰硫脲嘧啶衍生物拮抗剂与趋化素受体CMKLR1和GPR1的结合模式相似

期刊:Journal of Medicinal Chemistry

影响因子:6.8

doi:10.1021/acs.jmedchem.5c00135

Schermeng, Tina; Fürll, Alexander; Liessmann, Fabian; von Bredow, Lukas; Stichel, Jan; Weaver, C David; Tretbar, Maik; Meiler, Jens; Beck-Sickinger, Annette G

发表日期：2025

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Further Structure-Activity Relationship of G Protein-Gated Inwardly Rectifying Potassium Channels 1/2 Activators: Synthesis and Biological Characterization of In Vitro Tool Compounds

G蛋白门控内向整流钾通道1/2激活剂的进一步构效关系研究：体外工具化合物的合成与生物学表征

期刊:ChemMedChem

影响因子:3.4

doi:10.1002/cmdc.202500037

Nahid, Sumaiya; Rahman, Fahad Imtiaz; Du, Yu; Spitznagel, Brittany D; Singh, Sandeep K; Chhonker, Yashpal S; Murry, Daryl J; Weaver, C David; Hopkins, Corey R

发表日期：2025

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Efficient Regioselective Synthesis of Benzimidazoles and Azabenzimidazoles to Enable the Rapid Development of Structure-Activity Relationships for Activation of SLACK Potassium Channels

高效区域选择性合成苯并咪唑和氮杂苯并咪唑，以快速建立SLACK钾通道激活的构效关系

影响因子:1.4

doi:10.1055/a-2586-6260

Peprah, Paul K; Spitznagel, Brittany D; Du, Yu; Nguyen, Dalena; Weaver, C David; Emmitte, Kyle A

发表日期：2025

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Heterozygous expression of a Kcnt1 gain-of-function variant has differential effects on SST- and PV-expressing cortical GABAergic neurons

Kcnt1功能获得性变异体的杂合表达对表达SST和PV的皮质GABA能神经元具有不同的影响

doi:10.1101/2023.10.11.561953

Shore, Amy N; Li, Keyong; Safari, Mona; Qunies, Alshaima'a M; Spitznagel, Brittany D; Weaver, C David; Emmitte, Kyle A; Frankel, Wayne N; Weston, Matthew C

发表日期：2024

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VU6036720: The First Potent and Selective In Vitro Inhibitor of Heteromeric Kir4.1/5.1 Inward Rectifier Potassium Channels

VU6036720：首个高效选择性异源Kir4.1/5.1内向整流钾通道体外抑制剂

期刊:Molecular Pharmacology

doi:10.1124/molpharm.121.000464

McClenahan, Samantha J; Kent, Caitlin N; Kharade, Sujay V; Isaeva, Elena; Williams, Jade C; Han, Changho; Terker, Andrew; Gresham, Robert 3rd; Lazarenko, Roman M; Days, Emily L; Romaine, Ian M; Bauer, Joshua A; Boutaud, Olivier; Sulikowski, Gary A; Harris, Raymond; Weaver, C David; Staruschenko, Alexander; Lindsley, Craig W; Denton, Jerod S

发表日期：2022

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Next-generation inward rectifier potassium channel modulators: discovery and molecular pharmacology

新一代内向整流钾通道调节剂：发现与分子药理学

期刊:American Journal of Physiology-Cell Physiology

影响因子:4.7

doi:10.1152/ajpcell.00548.2020

Weaver, C David; Denton, Jerod S

发表日期：2021

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Discovery, synthesis and biological characterization of a series of N-(1-(1,1-dioxidotetrahydrothiophen-3-yl)-3-methyl-1H-pyrazol-5-yl)acetamide ethers as novel GIRK1/2 potassium channel activators

发现、合成并表征了一系列 N-(1-(1,1-二氧四氢噻吩-3-基)-3-甲基-1H-吡唑-5-基)乙酰胺醚作为新型 GIRK1/2 钾通道激活剂的生物学特性

期刊:RSC Medicinal Chemistry

影响因子:3.6

doi:10.1039/d1md00129a

Sharma, Swagat; Lesiak, Lauren; Aretz, Christopher D; Du, Yu; Kumar, Sushil; Gautam, Nagsen; Alnouti, Yazen; Dhuria, Nikilesh V; Chhonker, Yashpal S; Weaver, C David; Hopkins, Corey R

发表日期：2021

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Characterization of VU0468554, a New Selective Inhibitor of Cardiac G Protein-Gated Inwardly Rectifying K(+) Channels

VU0468554 的特性分析：一种新型选择性心脏 G 蛋白门控内向整流 K(+) 通道抑制剂

期刊:Molecular Pharmacology

doi:10.1124/molpharm.121.000311

Anderson, Allison; Vo, Baovi N; Marron Fernandez de Velasco, Ezequiel; Hopkins, Corey R; Weaver, C David; Wickman, Kevin

发表日期：2021

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Analgesic Effects of the GIRK Activator, VU0466551, Alone and in Combination with Morphine in Acute and Persistent Pain Models

GIRK 激活剂 VU0466551 单独使用及与吗啡联合使用在急性及持续性疼痛模型中的镇痛效果

期刊:ACS Chemical Neuroscience

影响因子:3.9

doi:10.1021/acschemneuro.8b00370

Abney, Kristopher K; Bubser, Michael; Du, Yu; Kozek, Krystian A; Bridges, Thomas M; Linsdley, Craig W; Daniels, J Scott; Morrison, Ryan D; Wickman, Kevin; Hopkins, Corey R; Jones, Carrie K; Weaver, C David

发表日期：2019

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