日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Interrelationship of Primary Virus Replication, Level of Latency, and Time to Reactivation in the Trigeminal Ganglia of Latently Infected Mice

潜伏感染小鼠三叉神经节中原发病毒复制、潜伏水平和再激活时间之间的相互关系

Matundan, Harry H; Mott, Kevin R; Allen, Sariah J; Wang, Shaohui; Bresee, Catherine J; Ghiasi, Yasamin N; Town, Terrence; Wechsler, Steven L; Ghiasi, Homayon

The Herpes Simplex Virus Latency-Associated Transcript Gene Is Associated with a Broader Repertoire of Virus-Specific Exhausted CD8+ T Cells Retained within the Trigeminal Ganglia of Latently Infected HLA Transgenic Rabbits

单纯疱疹病毒潜伏相关转录基因与潜伏感染的HLA转基因兔三叉神经节内保留的更广泛的病毒特异性耗竭CD8+ T细胞库相关

Srivastava, Ruchi; Dervillez, Xavier; Khan, Arif A; Chentoufi, Aziz A; Chilukuri, Sravya; Shukr, Nora; Fazli, Yasmin; Ong, Nicolas N; Afifi, Rasha E; Osorio, Nelson; Geertsema, Roger; Nesburn, Anthony B; Wechsler, Steven L; BenMohamed, Lbachir

Confocal Microscopic Analysis of a Rabbit Eye Model of High-Incidence Recurrent Herpes Stromal Keratitis

利用共聚焦显微镜分析兔眼高发复发性疱疹性基质角膜炎模型

Jester, James V; Morishige, Naoyuki; BenMohamed, Lbachir; Brown, Donald J; Osorio, Nelson; Hsiang, Chinhui; Perng, Guey Chuen; Jones, Clinton; Wechsler, Steven L

Large Amounts of Reactivated Virus in Tears Precedes Recurrent Herpes Stromal Keratitis in Stressed Rabbits Latently Infected with Herpes Simplex Virus

压力过大的、潜伏感染单纯疱疹病毒的兔子,其泪液中大量病毒的激活是复发性疱疹性基质角膜炎的前兆。

Perng, Guey-Chuen; Osorio, Nelson; Jiang, Xianzhi; Geertsema, Roger; Hsiang, Chinhui; Brown, Don; BenMohamed, Lbachir; Wechsler, Steven L

Prior Corneal Scarification and Injection of Immune Serum are Not Required Before Ocular HSV-1 Infection for UV-B-Induced Virus Reactivation and Recurrent Herpetic Corneal Disease in Latently Infected Mice

对于潜伏感染小鼠,UV-B诱导的病毒再激活和复发性疱疹性角膜疾病无需事先进行角膜划痕和注射免疫血清即可进行眼部HSV-1感染。

BenMohamed, Lbachir; Osorio, Nelson; Khan, Arif A; Srivastava, Ruchi; Huang, Lei; Krochmal, John J; Garcia, Jairo M; Simpson, Jennifer L; Wechsler, Steven L

A Herpes Simplex Virus Type 1 Human Asymptomatic CD8+ T-Cell Epitopes-Based Vaccine Protects Against Ocular Herpes in a "Humanized" HLA Transgenic Rabbit Model

一种基于1型单纯疱疹病毒人无症状CD8+ T细胞表位的疫苗可在“人源化”HLA转基因兔模型中预防眼部疱疹。

Srivastava, Ruchi; Khan, Arif A; Huang, Jiawei; Nesburn, Anthony B; Wechsler, Steven L; BenMohamed, Lbachir

Therapeutic immunization with a mixture of herpes simplex virus 1 glycoprotein D-derived “asymptomatic” human CD8+ T-cell epitopes decreases spontaneous ocular shedding in latently infected HLA transgenic rabbits: association with low frequency of local PD-1+ TIM-3+ CD8+ exhausted T cells

用单纯疱疹病毒1型糖蛋白D衍生的“无症状”人CD8+ T细胞表位混合物进行治疗性免疫,可降低潜伏感染HLA转基因兔的自发性眼部脱落:与局部PD-1+ TIM-3+ CD8+耗竭T细胞频率低相关

Khan, Arif A; Srivastava, Ruchi; Chentoufi, Aziz A; Geertsema, Roger; Thai, Nhi Thi Uyen; Dasgupta, Gargi; Osorio, Nelson; Kalantari, Mina; Nesburn, Anthony B; Wechsler, Steven L; BenMohamed, Lbachir

Decreased reactivation of a herpes simplex virus type 1 (HSV-1) latency-associated transcript (LAT) mutant using the in vivo mouse UV-B model of induced reactivation

利用体内小鼠 UV-B 诱导再激活模型,降低单纯疱疹病毒 1 型 (HSV-1) 潜伏相关转录物 (LAT) 突变体的再激活率

BenMohamed, Lbachir; Osorio, Nelson; Srivastava, Ruchi; Khan, Arif A; Simpson, Jennifer L; Wechsler, Steven L

Interactions between herpesvirus entry mediator (TNFRSF14) and latency-associated transcript during herpes simplex virus 1 latency

单纯疱疹病毒1型潜伏期疱疹病毒进入介质(TNFRSF14)与潜伏相关转录本之间的相互作用

Allen, Sariah J; Rhode-Kurnow, Antje; Mott, Kevin R; Jiang, Xianzhi; Carpenter, Dale; Rodriguez-Barbosa, J Ignacio; Jones, Clinton; Wechsler, Steven L; Ware, Carl F; Ghiasi, Homayon

Asymptomatic HLA-A*02:01-restricted epitopes from herpes simplex virus glycoprotein B preferentially recall polyfunctional CD8+ T cells from seropositive asymptomatic individuals and protect HLA transgenic mice against ocular herpes

来自单纯疱疹病毒糖蛋白B的无症状HLA-A*02:01限制性表位优先激活血清阳性无症状个体的多功能CD8+ T细胞,并保护HLA转基因小鼠免受眼部疱疹病毒感染。

Dervillez, Xavier; Qureshi, Huma; Chentoufi, Aziz A; Khan, Arif A; Kritzer, Elizabeth; Yu, David C; Diaz, Oscar R; Gottimukkala, Chetan; Kalantari, Mina; Villacres, Maria C; Scarfone, Vanessa M; McKinney, Denise M; Sidney, John; Sette, Alessandro; Nesburn, Anthony B; Wechsler, Steven L; BenMohamed, Lbachir