日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

A quantitative Lewy-fold-specific alpha-synuclein seed amplification assay as a progression marker for Parkinson's disease.

定量路易体特异性α-突触核蛋白种子扩增检测作为帕金森病进展标志物

期刊:Acta Neuropathologica
影响因子:9.3
doi:10.1007/s00401-025-02853-y
Bernhardt Alexander M, Longen Sebastian, Trossbach Svenja V, Rossi Marcello, Weckbecker Daniel, Schmidt Felix, Jäck Alexander, Katzdobler Sabrina, Fietzek Urban M, Weidinger Endy, Palleis Carla, Ruf Viktoria, Baiardi Simone, Parchi Piero, Höglinger Günter U, Matthias Torsten, Levin Johannes, Giese Armin
免疫/内分泌
发表日期：2025
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Safety, tolerability and pharmacokinetics of the oligomer modulator anle138b with exposure levels sufficient for therapeutic efficacy in a murine Parkinson model: A randomised, double-blind, placebo-controlled phase 1a trial

在小鼠帕金森病模型中，暴露水平足以达到治疗效果的寡聚体调节剂anle138b的安全性、耐受性和药代动力学：一项随机、双盲、安慰剂对照的1a期试验

期刊:EBioMedicine
影响因子:10.8
doi:10.1016/j.ebiom.2022.104021
Levin, Johannes; Sing, Nand; Melbourne, Sue; Morgan, Amber; Mariner, Carla; Spillantini, Maria Grazia; Wegrzynowicz, Michal; Dalley, Jeffrey W; Langer, Simon; Ryazanov, Sergey; Leonov, Andrei; Griesinger, Christian; Schmidt, Felix; Weckbecker, Daniel; Prager, Kai; Matthias, Torsten; Giese, Armin
帕金森
神经科学
发表日期：2022
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[(11)C]MODAG-001-towards a PET tracer targeting α-synuclein aggregates

[(11)C]MODAG-001——一种靶向α-突触核蛋白聚集体的PET示踪剂

期刊:European Journal of Nuclear Medicine and Molecular Imaging
影响因子:7.6
doi:10.1007/s00259-020-05133-x
Kuebler, Laura; Buss, Sabrina; Leonov, Andrei; Ryazanov, Sergey; Schmidt, Felix; Maurer, Andreas; Weckbecker, Daniel; Landau, Anne M; Lillethorup, Thea P; Bleher, Daniel; Saw, Ran Sing; Pichler, Bernd J; Griesinger, Christian; Giese, Armin; Herfert, Kristina
神经科学
发表日期：2021
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(11) C Radiolabeling of anle253b: a Putative PET Tracer for Parkinson's Disease That Binds to α-Synuclein Fibrils in vitro and Crosses the Blood-Brain Barrier

（11）C放射性标记anle253b：一种用于帕金森病的假定PET示踪剂，可在体外与α-突触核蛋白原纤维结合并穿过血脑屏障

期刊:ChemMedChem
影响因子:3.4
doi:10.1002/cmdc.201900689
Maurer, Andreas; Leonov, Andrei; Ryazanov, Sergey; Herfert, Kristina; Kuebler, Laura; Buss, Sabrina; Schmidt, Felix; Weckbecker, Daniel; Linder, Ruth; Bender, Dirk; Giese, Armin; Pichler, Bernd J; Griesinger, Christian
血脑屏障
帕金森
神经科学
发表日期：2020
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Potential sources of interference with the highly sensitive detection and quantification of alpha-synuclein seeds by qRT-QuIC

qRT-QuIC检测和定量α-突触核蛋白种子时可能存在的干扰因素

期刊:FEBS Open Bio
影响因子:2.3
doi:10.1002/2211-5463.12844
Ruf, Viktoria C; Shi, Song; Schmidt, Felix; Weckbecker, Daniel; Nübling, Georg S; Ködel, Uwe; Mollenhauer, Brit; Giese, Armin
神经科学
发表日期：2020
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