Weckerly相关文献与解析，生知库 | 链接生命科学的每一步

In Cellulo pharmacological profiling and genomic editing reveals paralog-specific targets for PA generation during PLC signaling.

在 Cellulo 中，药理学分析和基因组编辑揭示了 PLC 信号传导过程中 PA 生成的旁系同源特异性靶点。

期刊:

影响因子:

doi:10.64898/2026.03.02.709100

Weckerly Claire C, Murtagh Olivia L, Swayhoover Tiernan, Pemberton Joshua G, Hsu Ku-Lung, Hammond Gerald R V

PILS-Nir1 is a sensitive phosphatidic acid biosensor that reveals mechanisms of lipid production

PILS-Nir1 是一种灵敏的磷脂酸生物传感器，可揭示脂质生成的机制。

期刊:Journal of Cell Biology

影响因子:7.4

doi:10.1083/jcb.202405174

Claire C Weckerly # ,Taylor A Rahn # ,Max Ehrlich ,Rachel C Wills ,Joshua G Pemberton ,Michael V Airola ,Gerald R V Hammond

发表日期：2025

文献求助收藏

Single-molecule lipid biosensors mitigate inhibition of endogenous effector proteins.

单分子脂质生物传感器可减轻内源性效应蛋白的抑制作用

期刊:Journal of Cell Biology

影响因子:6.4

doi:10.1083/jcb.202412026

Holmes Victoria L, Ricci Morgan M C, Weckerly Claire C, Worcester Michael, Hammond Gerald R V

其它

发表日期：2025

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Quantitative comparison of PI(3,5)P(2) biosensors reveals SnxA is the most sensitive and unbiased

对PI(3,5)P(2)生物传感器的定量比较表明，SnxA是最灵敏且无偏的。

期刊:

影响因子:

doi:10.1101/2025.11.10.687688

Swayhoover, Tiernan; Weckerly, Claire C; Hammond, Gerald R V

发表日期：2025

文献求助收藏

Stereoselective Degradation of Diacylglycerol Kinases Potentiate T cell Activation and Tumor Cell Cytotoxicity

二酰甘油激酶的立体选择性降解可增强T细胞活化和肿瘤细胞毒性

期刊:

影响因子:

doi:10.64898/2025.12.09.692983

Shaikh, Minhaj; Mookherjee, Surya Pravo; Weckerly, Claire C; Libby, Adam H; Xiao, Aizhen; Zhao, Yunge; Vaidya, Sagar D; Kim, AeRyon; Li, Zhihong; Ware, Madeleine L; Marants, Michelle; Murtagh, Olivia L; Wolfe, Wesley J; Bullock, Timothy Nj; Purow, Benjamin W; Hammond, Gerald R V; Hsu, Ku-Lung

Nir1-LNS2 is a novel phosphatidic acid biosensor that reveals mechanisms of lipid production

Nir1-LNS2 是一种新型磷脂酸生物传感器，可揭示脂质产生的机制

期刊:

影响因子:

doi:10.1101/2024.02.28.582557

Claire C Weckerly, Taylor A Rahn, Max Ehrlich, Rachel C Wills, Joshua G Pemberton, Michael V Airola, Gerald R V Hammond

信号转导

发表日期：2024

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Molding a PI(3,5)P2 biosensor

PI(3,5)P2生物传感器的成型

期刊:Journal of Cell Biology

影响因子:6.4

doi:10.1083/jcb.202308004

Weckerly, Claire C; Hammond, Gerald R V

发表日期：2023

文献求助收藏

WNK kinases sense molecular crowding and rescue cell volume via phase separation

WNK 激酶感知分子拥挤并通过相分离拯救细胞体积

期刊:Cell

影响因子:45.5

doi:10.1016/j.cell.2022.09.042

Cary R Boyd-Shiwarski, Daniel J Shiwarski, Shawn E Griffiths, Rebecca T Beacham, Logan Norrell, Daryl E Morrison, Jun Wang, Jacob Mann, William Tennant, Eric N Anderson, Jonathan Franks, Michael Calderon, Kelly A Connolly, Muhammad Umar Cheema, Claire J Weaver, Lubika J Nkashama, Claire C Weckerly,

Subcellular Cartography of the Phosphoinositide Multiverse

磷脂酰肌醇多元宇宙的亚细胞图谱

Pregnancy and Lactation Associated Osteoporosis of the Hip: A Systematic Review

妊娠和哺乳期髋关节骨质疏松症：系统评价

In Cellulo pharmacological profiling and genomic editing reveals paralog-specific targets for PA generation during PLC signaling.

在 Cellulo 中，药理学分析和基因组编辑揭示了 PLC 信号传导过程中 PA 生成的旁系同源特异性靶点。

PILS-Nir1 is a sensitive phosphatidic acid biosensor that reveals mechanisms of lipid production

PILS-Nir1 是一种灵敏的磷脂酸生物传感器，可揭示脂质生成的机制。

Single-molecule lipid biosensors mitigate inhibition of endogenous effector proteins.

单分子脂质生物传感器可减轻内源性效应蛋白的抑制作用

Quantitative comparison of PI(3,5)P(2) biosensors reveals SnxA is the most sensitive and unbiased

对PI(3,5)P(2)生物传感器的定量比较表明，SnxA是最灵敏且无偏的。

Stereoselective Degradation of Diacylglycerol Kinases Potentiate T cell Activation and Tumor Cell Cytotoxicity

二酰甘油激酶的立体选择性降解可增强T细胞活化和肿瘤细胞毒性

Nir1-LNS2 is a novel phosphatidic acid biosensor that reveals mechanisms of lipid production

Nir1-LNS2 是一种新型磷脂酸生物传感器，可揭示脂质产生的机制

Molding a PI(3,5)P2 biosensor

PI(3,5)P2生物传感器的成型

WNK kinases sense molecular crowding and rescue cell volume via phase separation

WNK 激酶感知分子拥挤并通过相分离拯救细胞体积