日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

DistRMI: a deep distance-aware neural network for explainable RNA loop motif-small molecule interaction prediction

DistRMI:一种用于预测可解释RNA环基序-小分子相互作用的深度距离感知神经网络

Liu, Zhaoxiang; Zhu, Qiqi; Tian, Qingyan; Zhong, Lei; Deng, Yingxiang; Wei, Dengguo; Fu, Haitao

The S2 Pocket Governs the Genus-Specific Substrate Selectivity of Coronavirus 3C-Like Protease

S2口袋控制冠状病毒3C样蛋白酶的属特异性底物选择性

Zhou, Junwei; Sun, Peng; Yang, Zhixiang; Wang, Taiquan; Guo, Jiahui; Qiu, Runhui; Li, Zhuang; Wei, Dengguo; Zheng, Jinshui; Peng, Guiqing; Fang, Liurong; Xiao, Shaobo

Unfolding of an RNA G-quadruplex motif in the negative strand genome of porcine reproductive and respiratory syndrome virus by host and viral helicases to promote viral replication.

宿主和病毒解旋酶解开猪繁殖与呼吸综合征病毒负链基因组中的 RNA G-四链体基序,从而促进病毒复制

Fang Puxian, Xie Congbao, Pan Ting, Cheng Ting, Chen Wei, Xia Sijin, Ding Tong, Fang Junkang, Zhou Yanrong, Fang Liurong, Wei Dengguo, Xiao Shaobo

In vivo dynamics and regulation of DNA G-quadruplex structures in mammals

哺乳动物体内DNA G-四链体结构的动态变化和调控

Zhang, Ze-Hao; Qian, Sheng Hu; Wei, Dengguo; Chen, Zhen-Xia

PDA-PRGCN: identification of Piwi-interacting RNA-disease associations through subgraph projection and residual scaling-based feature augmentation

PDA-PRGCN:通过子图投影和基于残差缩放的特征增强来识别Piwi相互作用RNA-疾病关联

Zhang, Ping; Sun, Weicheng; Wei, Dengguo; Li, Guodong; Xu, Jinsheng; You, Zhuhong; Zhao, Bowei; Li, Li

Native de novo structural determinations of non-canonical nucleic acid motifs by X-ray crystallography at long wavelengths

利用长波长X射线晶体衍射技术对非典型核酸基序进行天然从头结构测定

Zhang, Yashu; El Omari, Kamel; Duman, Ramona; Liu, Sisi; Haider, Shozeb; Wagner, Armin; Parkinson, Gary N; Wei, Dengguo

G(2)-quadruplex in the 3'UTR of IE180 regulates Pseudorabies virus replication by enhancing gene expression

IE180 3'UTR 中的 G(2)-四链体通过增强基因表达来调控伪狂犬病毒复制。

Zhang, Yashu; Liu, Sisi; Jiang, Hui; Deng, Hui; Dong, Chen; Shen, Wei; Chen, Haifeng; Gao, Chao; Xiao, Shaobo; Liu, Zheng-Fei; Wei, Dengguo

Flexibility and structural conservation in a c-KIT G-quadruplex

c-KIT G-四链体的灵活性和结构保守性。

Wei, Dengguo; Husby, Jarmila; Neidle, Stephen

Small-molecule binding to the DNA minor groove is mediated by a conserved water cluster

小分子与DNA小沟的结合是由一个保守的水簇介导的。

Wei, DengGuo; Wilson, W David; Neidle, Stephen

Crystal structure of a c-kit promoter quadruplex reveals the structural role of metal ions and water molecules in maintaining loop conformation

c-kit启动子四链体的晶体结构揭示了金属离子和水分子在维持环状构象中的结构作用

Wei, Dengguo; Parkinson, Gary N; Reszka, Anthony P; Neidle, Stephen