日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Dissection of Gαs and Hedgehog Signaling Cross-talk Reveals Therapeutic Opportunities to Target Hedgehog-Dependent Tumors

对 Gαs 和 Hedgehog 信号通路相互作用的剖析揭示了靶向 Hedgehog 依赖性肿瘤的治疗机会

期刊:Cancer Research
影响因子:16.6
doi:10.1158/0008-5472.CAN-25-1109
Krantz, Sarah; Bell, Braden A; Lund, Katherine; Salinas Parra, Natalia; Ng, Yeap; De Oliveira Rosa, Natalia; Mukhopadhyay, Saikat; St Croix, Brad; Sarin, Kavita Y; Weigert, Roberto; Raimondi, Francesco; Iglesias-Bartolome, Ramiro
信号转导
Hedgehog
肿瘤
肿瘤免疫
发表日期：2026
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Spatially Distinct Myosin II Architectures Regulate Protrusion Dynamics and Directional Persistence during Immune Cell Migration

空间上不同的肌球蛋白II结构调控免疫细胞迁移过程中的突起动力学和方向性持久性

期刊:
影响因子:
doi:10.64898/2026.03.13.711384
Melis, Nicolas; Chen, Desu; Chen, Emily; Madsen, Thomas; Ng, Yeap; Subramanian, Bhagawat; Wang, Weiye; Parent, Carole; Losert, Wolfgang; Weigert, Roberto
信号转导
细胞生物学
免疫/内分泌
发表日期：2026
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Control of epithelial tissue organization by mRNA localization.

通过mRNA定位控制上皮组织结构

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-60532-8
Mason Devon E, Madsen Thomas D, Gasparski Alexander N, Kong Dong, Jiwnani Neal, Lechler Terry, Loncarek Jadranka, Weigert Roberto, Iglesias-Bartolome Ramiro, Mili Stavroula
其它
发表日期：2025
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TRAIL induces cytokine production via the NFkB2 pathway promoting neutrophil chemotaxis and neutrophil-mediated immune-suppression in triple negative breast cancer cells

TRAIL通过NF-κB2通路诱导细胞因子产生，促进中性粒细胞趋化和中性粒细胞介导的免疫抑制，从而增强三阴性乳腺癌细胞的免疫活性。

期刊:Cancer Letters
影响因子:10.1
doi:10.1016/j.canlet.2025.217692
Kundu, Manjari; Greer, Yoshimi E; Lobanov, Alexei; Ridnour, Lisa; Donahue, Renee N; Ng, Yeap; Ratnayake, Shashi; White, Karley; Voeller, Donna; Weltz, Sarah; Chen, Qingrong; Lockett, Stephen J; Cam, Maggie; Meerzaman, Daoud; Wink, David A; Weigert, Roberto; Lipkowitz, Stanley
肿瘤
中性粒细胞
肿瘤免疫
信号转导
乳腺癌
粒细胞
TRAIL
细胞生物学
免疫/内分泌
发表日期：2025
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CDK2 inhibition produces a persistent population of polyploid cancer cells.

CDK2 抑制会导致多倍体癌细胞持续存在

期刊:JCI Insight
影响因子:6.1
doi:10.1172/jci.insight.189901
Tyutyunyk-Massey Liliya, Chen Zibo, Liu Xiuxia, Kawakami Masanori, Harned Adam, Ng Yeap, Luke Brian, Okpechi Samuel C, Ogunlade Blessing, Alfaro Yair, Weigert Roberto, Narayan Kedar, Liu Xi, Dmitrovsky Ethan
细胞生物学
CDK2
肿瘤免疫
发表日期：2025
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Longitudinal Imaging of the Premalignant Tumor Microenvironment Reveals Transient Myeloid States Predictive of Tumor Fate

对癌前肿瘤微环境的纵向成像揭示了可预测肿瘤命运的瞬时髓系状态

期刊:
影响因子:
doi:10.1101/2025.11.02.686127
Madsen, Thomas D; Chen, Desu; Hernandez, Maria; Hammoudeh, Sarah; Heydecker, Marco; Chen, Emily; Abu-Elnaj, Salma; Kedei, Noemi; Wang, Weiye; Weigert, Roberto
肿瘤
肿瘤微环境
肿瘤免疫
发表日期：2025
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Dissection of Gαs and Hedgehog signaling crosstalk reveals therapeutic opportunities to target adenosine receptor 2b in Hedgehog-dependent tumors.

对 Gαs 和 Hedgehog 信号通路串扰的剖析揭示了针对 Hedgehog 依赖性肿瘤中腺苷受体 2b 的治疗机会

期刊:
影响因子:
doi:10.1101/2025.02.21.639530
Krantz Sarah, Bell Braden, Lund Katherine, Parra Natalia Salinas, Ng Yeap, De Oliveira Rosa Natalia, Mukhopadhyay Saikat, Croix Brad St, Sarin Kavita Y, Weigert Roberto, Raimondi Francesco, Iglesias-Bartolome Ramiro
信号转导
肿瘤
Hedgehog
肿瘤免疫
发表日期：2025
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Intravital imaging of muscle damage and response to therapy in a model of Pompe disease

在庞贝病模型中，通过活体成像技术观察肌肉损伤和治疗反应。

期刊:Clinical and Translational Medicine
影响因子:6.8
doi:10.1002/ctm2.1561
Meena, Naresh K; Ng, Yeap; Randazzo, Davide; Weigert, Roberto; Puertollano, Rosa; Raben, Nina
发表日期：2024
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Coordination of force-generating actin-based modules stabilizes and remodels membranes in vivo

肌动蛋白基力生成模块的协调作用可在体内稳定和重塑细胞膜。

期刊:Journal of Cell Biology
影响因子:6.4
doi:10.1083/jcb.202401091
Heydecker, Marco; Shitara, Akiko; Chen, Desu; Tran, Duy T; Masedunskas, Andrius; Tora, Muhibullah S; Ebrahim, Seham; Appaduray, Mark A; Galeano Niño, Jorge Luis; Bhardwaj, Abhishek; Narayan, Kedar; Hardeman, Edna C; Gunning, Peter W; Weigert, Roberto
细胞生物学
发表日期：2024
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Components of the Endosome-Lysosome Vesicular Machinery as Drivers of the Metastatic Cascade in Prostate Cancer

内体-溶酶体囊泡机制的组成部分在前列腺癌转移级联反应中的作用

期刊:Cancers
影响因子:4.4
doi:10.3390/cancers17010043
Nturubika, Bukuru Dieu-Donne; Logan, Jessica; Johnson, Ian R D; Moore, Courtney; Li, Ka Lok; Tang, Jingying; Lam, Giang; Parkinson-Lawrence, Emma; Williams, Desmond B; Chakiris, James; Hindes, Madison; Brooks, Robert D; Miles, Mark A; Selemidis, Stavros; Gregory, Philip; Weigert, Roberto; Butler, Lisa; Ward, Mark P; Waugh, David J J; O'Leary, John J; Brooks, Douglas A
肿瘤
肿瘤免疫
信号转导
囊泡
前列腺癌
发表日期：2024
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