日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

CCR10 expression is required for the adjuvant activity of the mucosal chemokine CCL28 when delivered in the context of an HIV-1 Env DNA vaccine

当黏膜趋化因子CCL28与HIV-1 Env DNA疫苗联合使用时,CCR10的表达是其发挥佐剂活性的必要条件。

Gary, E N; Kathuria, N; Makurumidze, G; Curatola, A; Ramamurthi, A; Bernui, M E; Myles, D; Yan, J; Pankhong, P; Muthumani, K; Haddad, E; Humeau, L; Weiner, D B; Kutzler, M A

Chemokine-adjuvanted electroporated DNA vaccine induces substantial protection from simian immunodeficiency virus vaginal challenge

趋化因子佐剂电穿孔DNA疫苗可显著保护机体免受猴免疫缺陷病毒阴道感染

Kutzler, M A; Wise, M C; Hutnick, N A; Moldoveanu, Z; Hunter, M; Reuter, M; Yuan, S; Yan, J; Ginsberg, A; Sylvester, A; Pahar, B; Carnathan, D; Kathuria, N; Khan, A S; Montefiori, D; Sardesai, N Y; Betts, M R; Mestecky, J; Marx, P; Weiner, D B

Immunogenicity of a novel enhanced consensus DNA vaccine encoding the leptospiral protein LipL45

编码钩端螺旋体蛋白LipL45的新型增强型共识DNA疫苗的免疫原性

Vijayachari, P; Vedhagiri, K; Mallilankaraman, K; Mathur, P P; Sardesai, N Y; Weiner, D B; Ugen, K E; Muthumani, K

Hydrodynamic immunization leads to poor CD8 T-cell expansion, low frequency of memory CTLs and ineffective antiviral protection

流体动力学免疫会导致 CD8 T 细胞扩增不良、记忆性 CTL 频率低以及抗病毒保护效果不佳。

Obeng-Adjei, N; Choo, D K; Weiner, D B

Inducing humoral and cellular responses to multiple sporozoite and liver-stage malaria antigens using exogenous plasmid DNA.

利用外源质粒DNA诱导对多种疟原虫孢子和肝期疟原虫抗原的体液和细胞反应

Ferraro B, Talbott K T, Balakrishnan A, Cisper N, Morrow M P, Hutnick N A, Myles D J, Shedlock D J, Obeng-Adjei N, Yan J, Kayatani A K K, Richie N, Cabrera W, Shiver R, Khan A S, Brown A S, Yang M, Wille-Reece U, Birkett A J, Sardesai N Y, Weiner D B

Synthetic DNA immunogen encoding hepatitis B core antigen drives immune response in liver

编码乙型肝炎核心抗原的合成DNA免疫原驱动肝脏免疫反应

Obeng-Adjei, N; Choo, D K; Saini, J; Yan, J; Pankhong, P; Parikh, A; Chu, J S; Weiner, D B

Molecular adjuvant HMGB1 enhances anti-influenza immunity during DNA vaccination

分子佐剂HMGB1可增强DNA疫苗接种期间的抗流感免疫力

Fagone, P; Shedlock, D J; Bao, H; Kawalekar, O U; Yan, J; Gupta, D; Morrow, M P; Patel, A; Kobinger, G P; Muthumani, K; Weiner, D B

Regression of subcutaneous B16 melanoma tumors after intratumoral delivery of an IL-15-expressing plasmid followed by in vivo electroporation

皮下B16黑色素瘤肿瘤在瘤内注射表达IL-15的质粒后,经体内电穿孔后出现消退

Ugen, K E; Kutzler, M A; Marrero, B; Westover, J; Coppola, D; Weiner, D B; Heller, R

Modulation of antigen-specific humoral responses in rhesus macaques by using cytokine cDNAs as DNA vaccine adjuvants

利用细胞因子cDNA作为DNA疫苗佐剂调节恒河猴抗原特异性体液免疫反应

Kim, J J; Yang, J S; VanCott, T C; Lee, D J; Manson, K H; Wyand, M S; Boyer, J D; Ugen, K E; Weiner, D B

Interleukin 7 can enhance antigen-specific cytotoxic-T-lymphocyte and/or Th2-type immune responses in vivo

白细胞介素 7 可在体内增强抗原特异性细胞毒性 T 淋巴细胞和/或 Th2 型免疫反应。

Sin, J I; Kim, J; Pachuk, C; Weiner, D B