日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Antibacterial macrocyclic peptides reveal a distinct mode of BamA inhibition

抗菌大环肽揭示了一种独特的BamA抑制模式

Walker, Morgan E; Zhu, Wei; Peterson, Janine H; Wang, Hao; Patteson, Jon; Soriano, Aileen; Zhang, Han; Mayhood, Todd; Hou, Yan; Mesbahi-Vasey, Samaneh; Gu, Meigang; Frost, John; Lu, Jun; Johnston, Jennifer; Hipolito, Christopher; Lin, Songnian; Painter, Ronald E; Klein, Daniel; Walji, Abbas; Weinglass, Adam; Kelly, Terri M; Saldanha, Adrian; Schubert, Jeffrey; Bernstein, Harris D; Walker, Scott S

N'‑(1-Phenylethylidene)benzohydrazide Cytotoxicity Is Lysine-Specific Demethylase 1 Independent and Linked to Iron-Sulfur Cluster Disruption in Ewing Sarcoma.

N'â€'(1-苯亚乙基)苯甲酰肼的细胞毒性与赖氨酸特异性去甲基酶 1 无关,并且与尤文氏肉瘤中的铁硫簇破坏有关。

Sherman John W, Rask Galen C, Xiong Bingcong, Tokarsky E John, Dreher Rachel D, Weinglass Aran, Hayes Colin, Duncan Aundrietta, Weerapana Eranthie, Theisen Emily R

A non-canonical mechanism of GPCR activation

GPCR激活的非经典机制

Powers, Alexander S; Khan, Aasma; Paggi, Joseph M; Latorraca, Naomi R; Souza, Sarah; Di Salvo, Jerry; Lu, Jun; Soisson, Stephen M; Johnston, Jennifer M; Weinglass, Adam B; Dror, Ron O

A non-canonical mechanism of GPCR activation

GPCR激活的非经典机制

Powers, Alexander S; Khan, Aasma; Paggi, Joseph M; Latorraca, Naomi R; Souza, Sarah; Salvo, Jerry Di; Lu, Jun; Soisson, Stephen M; Johnston, Jennifer M; Weinglass, Adam B; Dror, Ron O

Attending to child agency in paediatric palliative care consultations: Adults' use of tag questions directed to the child

在儿科姑息治疗咨询中关注儿童的自主性:成人对儿童使用附加问题

Ekberg, Katie; Ekberg, Stuart; Weinglass, Lara; Herbert, Anthony; Rendle-Short, Johanna; Bluebond-Langner, Myra; Yates, Patsy; Bradford, Natalie; Danby, Susan

GPR120 suppresses adipose tissue lipolysis and synergizes with GPR40 in antidiabetic efficacy

GPR120 抑制脂肪组织脂肪分解并与 GPR40 协同发挥抗糖尿病功效

Santhosh Satapati, Ying Qian, Margaret S Wu, Aleksandr Petrov, Ge Dai, Sheng-Ping Wang, Yonghua Zhu, Xiaolan Shen, Eric S Muise, Ying Chen, Emanuel Zycband, Adam Weinglass, Jerry Di Salvo, John S Debenham, Jason M Cox, Ping Lan, Vinit Shah, Stephen F Previs, Mark Erion, David E Kelley, Liangsu Wang,

Design and Synthesis of Novel, Selective GPR40 AgoPAMs

新型选择性GPR40 AgoPAMs的设计与合成

Plummer, Christopher W; Clements, Matthew J; Chen, Helen; Rajagopalan, Murali; Josien, Hubert; Hagmann, William K; Miller, Michael; Trujillo, Maria E; Kirkland, Melissa; Kosinski, Daniel; Mane, Joel; Pachanski, Michele; Cheewatrakoolpong, Boonlert; Nolting, Andrew F; Orr, Robert; Christensen, Melodie; Campeau, Louis-Charles; Wright, Michael J; Bugianesi, Randal; Souza, Sarah; Zhang, Xiaoping; Di Salvo, Jerry; Weinglass, Adam B; Tschirret-Guth, Richard; Nargund, Ravi; Howard, Andrew D; Colletti, Steven L

GPR40 partial agonist MK-2305 lower fasting glucose in the Goto Kakizaki rat via suppression of endogenous glucose production

GPR40 部分激动剂 MK-2305 通过抑制内源性葡萄糖生成降低 Goto Kakizaki 大鼠的空腹血糖

Corin Miller, Michele J Pachanski, Melissa E Kirkland, Daniel T Kosinski, Joel Mane, Michelle Bunzel, Jin Cao, Sarah Souza, Brande Thomas-Fowlkes, Jerry Di Salvo, Adam B Weinglass, Xiaoyan Li, Robert W Myers, Kevin Knagge, Paul E Carrington, William K Hagmann, Maria E Trujillo

GPR40 partial agonists and AgoPAMs: Differentiating effects on glucose and hormonal secretions in the rodent

GPR40 部分激动剂和 AgoPAM:对啮齿动物葡萄糖和激素分泌的不同影响

Michele J Pachanski, Melissa E Kirkland, Daniel T Kosinski, Joel Mane, Boonlert Cheewatrakoolpong, Jiyan Xue, Daphne Szeto, Gail Forrest, Corin Miller, Michelle Bunzel, Christopher W Plummer, Harry R Chobanian, Michael W Miller, Sarah Souza, Brande S Thomas-Fowlkes, Aimie M Ogawa, Adam B Weinglass, 

GPR40 (FFAR1) - Combined Gs and Gq signaling in vitro is associated with robust incretin secretagogue action ex vivo and in vivo

GPR40 (FFAR1)——体外Gs和Gq信号通路的联合激活与体内外强大的肠促胰岛素促分泌作用相关。

Hauge, Maria; Vestmar, Marie A; Husted, Anna S; Ekberg, Jeppe P; Wright, Michael J; Di Salvo, Jerry; Weinglass, Adam B; Engelstoft, Maja S; Madsen, Andreas N; Lückmann, Michael; Miller, Michael W; Trujillo, Maria E; Frimurer, Thomas M; Holst, Birgitte; Howard, Andrew D; Schwartz, Thue W