日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Reciprocal metabolic perturbations in the adipose tissue and liver of GPIHBP1-deficient mice

GPIHBP1缺陷小鼠脂肪组织和肝脏中相互代谢紊乱

Weinstein, Michael M; Goulbourne, Christopher N; Davies, Brandon S J; Tu, Yiping; Barnes, Richard H 2nd; Watkins, Steven M; Davis, Ryan; Reue, Karen; Tontonoz, Peter; Beigneux, Anne P; Fong, Loren G; Young, Stephen G

Early hepatic insulin resistance precedes the onset of diabetes in obese C57BLKS-db/db mice.

肥胖的 C57BLKS-db/db 小鼠出现早期肝脏胰岛素抵抗之前,糖尿病尚未发生

Davis Richard C, Castellani Lawrence W, Hosseini Maryam, Ben-Zeev Osnat, Mao Hui Z, Weinstein Michael M, Jung Dae Young, Jun John Y, Kim Jason K, Lusis Aldons J, Péterfy Miklós

Cholesterol intake modulates plasma triglyceride levels in glycosylphosphatidylinositol HDL-binding protein 1-deficient mice

胆固醇摄入量调节糖基磷脂酰肌醇高密度脂蛋白结合蛋白1缺陷小鼠的血浆甘油三酯水平

Weinstein, Michael M; Tu, Yiping; Beigneux, Anne P; Davies, Brandon S J; Gin, Peter; Voss, Constance; Walzem, Rosemary L; Reue, Karen; Tontonoz, Peter; Bensadoun, André; Fong, Loren G; Young, Stephen G

Intravenous injection of apolipoprotein A-V reconstituted high-density lipoprotein decreases hypertriglyceridemia in apoav-/- mice and requires glycosylphosphatidylinositol-anchored high-density lipoprotein-binding protein 1

静脉注射载脂蛋白AV重组高密度脂蛋白可降低apoav-/-小鼠的高甘油三酯血症,且该过程需要糖基磷脂酰肌醇锚定的高密度脂蛋白结合蛋白1。

Shu, Xiao; Nelbach, Lisa; Weinstein, Michael M; Burgess, Braydon L; Beckstead, Jennifer A; Young, Stephen G; Ryan, Robert O; Forte, Trudy M

Chylomicronemia elicits atherosclerosis in mice--brief report

乳糜微粒血症诱发小鼠动脉粥样硬化——简报

Weinstein, Michael M; Yin, Liya; Tu, Yiping; Wang, Xuping; Wu, Xiaohui; Castellani, Lawrence W; Walzem, Rosemary L; Lusis, Aldons J; Fong, Loren G; Beigneux, Anne P; Young, Stephen G

Direct synthesis of lamin A, bypassing prelamin a processing, causes misshapen nuclei in fibroblasts but no detectable pathology in mice

直接合成层粘蛋白A,绕过前层粘蛋白A的加工过程,会导致成纤维细胞核畸形,但在小鼠中未检测到病理变化。

Coffinier, Catherine; Jung, Hea-Jin; Li, Ziwei; Nobumori, Chika; Yun, Ui Jeong; Farber, Emily A; Davies, Brandon S; Weinstein, Michael M; Yang, Shao H; Lammerding, Jan; Farahani, Javad N; Bentolila, Laurent A; Fong, Loren G; Young, Stephen G

Significantly reduced CCR5-tropic HIV-1 replication in vitro in cells from subjects previously immunized with Vaccinia Virus

在先前接种过痘苗病毒的受试者的细胞中,体外CCR5嗜性HIV-1复制显著降低

Weinstein, Raymond S; Weinstein, Michael M; Alibek, Kenneth; Bukrinsky, Michael I; Brichacek, Beda

Chylomicronemia with a mutant GPIHBP1 (Q115P) that cannot bind lipoprotein lipase

乳糜微粒血症伴有突变型 GPIHBP1 (Q115P),该突变型 GPIHBP1 无法结合脂蛋白脂肪酶

Beigneux, Anne P; Franssen, Remco; Bensadoun, André; Gin, Peter; Melford, Kristan; Peter, Jorge; Walzem, Rosemary L; Weinstein, Michael M; Davies, Brandon S J; Kuivenhoven, Jan A; Kastelein, John J P; Fong, Loren G; Dallinga-Thie, Geesje M; Young, Stephen G

Glycosylation of Asn-76 in mouse GPIHBP1 is critical for its appearance on the cell surface and the binding of chylomicrons and lipoprotein lipase.

小鼠 GPIHBP1 中 Asn-76 的糖基化对于其在细胞表面的出现以及乳糜微粒和脂蛋白脂肪酶的结合至关重要

Beigneux Anne P, Gin Peter, Davies Brandon S J, Weinstein Michael M, Bensadoun André, Ryan Robert O, Fong Loren G, Young Stephen G

The acidic domain of GPIHBP1 is important for the binding of lipoprotein lipase and chylomicrons.

GPIHBP1 的酸性结构域对于脂蛋白脂肪酶和乳糜微粒的结合至关重要

Gin Peter, Yin Liya, Davies Brandon S J, Weinstein Michael M, Ryan Robert O, Bensadoun André, Fong Loren G, Young Stephen G, Beigneux Anne P