日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The Degradation of Botulinum Neurotoxin Light Chains Using PROTACs

利用PROTACs降解肉毒杆菌神经毒素轻链

Tsai, Yien Che; Kozar, Loren; Mawi, Zo P; Ichtchenko, Konstantin; Shoemaker, Charles B; McNutt, Patrick M; Weissman, Allan M

Differential sensitivity of the yeast Lon protease Pim1p to impaired mitochondrial respiration

酵母Lon蛋白酶Pim1p对线粒体呼吸功能受损的差异敏感性

Metzger, Meredith B; Scales, Jessica L; Grant, Garis A; Molnar, Abigail E; Loncarek, Jadranka; Weissman, Allan M

Protein Engineering in the Ubiquitin System: Tools for Discovery and Beyond

泛素系统中的蛋白质工程:发现及其他应用的工具

Zhao, Bo; Tsai, Yien Che; Jin, Bo; Wang, Bufan; Wang, Yiyang; Zhou, Han; Carpenter, Tomaya; Weissman, Allan M; Yin, Jun

A protein quality control pathway at the mitochondrial outer membrane

线粒体外膜上的蛋白质质量控制通路

Metzger, Meredith B; Scales, Jessica L; Dunklebarger, Mitchell F; Loncarek, Jadranka; Weissman, Allan M

Stabilization of p27(Kip1)/CDKN1B by UBCH7/UBE2L3 catalyzed ubiquitinylation: a new paradigm in cell-cycle control

UBCH7/UBE2L3催化的泛素化作用稳定p27(Kip1)/CDKN1B:细胞周期调控的新范式

Whitcomb, Elizabeth A; Tsai, Yien Che; Basappa, Johnvesly; Liu, Ke; Le Feuvre, Aurélie K; Weissman, Allan M; Taylor, Allen

Crystal structure of the Schizosaccharomyces pombe U7BR E2-binding region in complex with Ubc7

裂殖酵母U7BR E2结合区与Ubc7复合物的晶体结构

Hann, Zachary S; Metzger, Meredith B; Weissman, Allan M; Lima, Christopher D

The Ubiquitin Ligase (E3) Psh1p Is Required for Proper Segregation of both Centromeric and Two-Micron Plasmids in Saccharomyces cerevisiae

酿酒酵母中泛素连接酶 (E3) Psh1p 是着丝粒质粒和 2 微米质粒正确分离所必需的

Metzger, Meredith B; Scales, Jessica L; Dunklebarger, Mitchell F; Weissman, Allan M

Insights into Ubiquitination from the Unique Clamp-like Binding of the RING E3 AO7 to the E2 UbcH5B.

从 RING E3 AO7 与 E2 UbcH5B 的独特钳状结合中了解泛素化

Li Shengjian, Liang Yu-He, Mariano Jennifer, Metzger Meredith B, Stringer Daniel K, Hristova Ventzislava A, Li Jess, Randazzo Paul A, Tsai Yien Che, Ji Xinhua, Weissman Allan M

Malfolded protein structure and proteostasis in lung diseases

肺部疾病中的蛋白质结构异常折叠和蛋白质稳态

Balch, William E; Sznajder, Jacob I; Budinger, Scott; Finley, Daniel; Laposky, Aaron D; Cuervo, Ana Maria; Benjamin, Ivor J; Barreiro, Esther; Morimoto, Richard I; Postow, Lisa; Weissman, Allan M; Gail, Dorothy; Banks-Schlegel, Susan; Croxton, Thomas; Gan, Weiniu

Ubiquitin ligase gp78 targets unglycosylated prion protein PrP for ubiquitylation and degradation

泛素连接酶gp78靶向未糖基化的朊病毒蛋白PrP,使其泛素化并降解。

Shao, Jia; Choe, Vitnary; Cheng, Haili; Tsai, Yien Che; Weissman, Allan M; Luo, Shiwen; Rao, Hai