日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Hypothalamic miR-1983 Targets Insulin Receptor β and the Insulin-mediated miR-1983 Increase Is Blocked by Metformin

下丘脑 miR-1983 靶向胰岛素受体 β,二甲双胍可阻断胰岛素介导的 miR-1983 增加

Jennifer A Chalmers, Prasad S Dalvi, Neruja Loganathan, Emma K McIlwraith, Leigh Wellhauser, Anaies Nazarians-Armavil, Judith A Eversley, Haneesha Mohan, Priska Stahel, Satya Dash, Michael B Wheeler, Denise D Belsham

A new platform for high-throughput therapy testing on iPSC-derived lung progenitor cells from cystic fibrosis patients

一种用于对囊性纤维化患者来源的iPSC衍生肺祖细胞进行高通量治疗测试的新平台

Jiang, Jia Xin; Wellhauser, Leigh; Laselva, Onofrio; Utkina, Irina; Bozoky, Zoltan; Gunawardena, Tarini; Ngan, Zoe; Xia, Sunny; Di Paola, Michelle; Eckford, Paul D W; Ratjen, Felix; Moraes, Theo J; Parkinson, John; Wong, Amy P; Bear, Christine E

Orkambi® and amplifier co-therapy improves function from a rare CFTR mutation in gene-edited cells and patient tissue

Orkambi® 和放大器联合疗法可改善基因编辑细胞和患者组织中罕见 CFTR 突变的功能

Steven V Molinski, Saumel Ahmadi, Wan Ip, Hong Ouyang, Adriana Villella, John P Miller, Po-Shun Lee, Kethika Kulleperuma, Kai Du, Michelle Di Paola, Paul Dw Eckford, Onofrio Laselva, Ling Jun Huan, Leigh Wellhauser, Ellen Li, Peter N Ray, Régis Pomès, Theo J Moraes, Tanja Gonska, Felix Ratjen, Chris

Phenotypic profiling of CFTR modulators in patient-derived respiratory epithelia

患者来源的呼吸道上皮中 CFTR 调节剂的表型分析

Saumel Ahmadi, Zoltan Bozoky, Michelle Di Paola, Sunny Xia, Canhui Li, Amy P Wong, Leigh Wellhauser, Steven V Molinski, Wan Ip, Hong Ouyang, Julie Avolio, Julie D Forman-Kay, Felix Ratjen, Jeremy A Hirota, Johanna Rommens, Janet Rossant, Tanja Gonska, Theo J Moraes, Christine E Bear

Nitric Oxide Exerts Basal and Insulin-Dependent Anorexigenic Actions in POMC Hypothalamic Neurons

一氧化氮在下丘脑POMC神经元中发挥基础和胰岛素依赖性厌食作用

Wellhauser, Leigh; Chalmers, Jennifer A; Belsham, Denise D

Activation of the omega-3 fatty acid receptor GPR120 mediates anti-inflammatory actions in immortalized hypothalamic neurons.

ω-3脂肪酸受体GPR120的激活介导永生化下丘脑神经元的抗炎作用

Wellhauser Leigh, Belsham Denise D

ATP induces conformational changes in the carboxyl-terminal region of ClC-5

ATP诱导ClC-5羧基末端区域发生构象变化

Wellhauser, Leigh; Luna-Chavez, Cesar; D'Antonio, Christina; Tainer, John; Bear, Christine E

Nucleotides bind to the C-terminus of ClC-5

核苷酸与ClC-5的C端结合

Wellhauser, Leigh; Kuo, Hsin-Hen; Stratford, Fiona L L; Ramjeesingh, Mohabir; Huan, Ling-Jun; Luong, Winnie; Li, Canhui; Deber, Charles M; Bear, Christine E